Current Evidence on Cell Death in Preterm Brain Injury in Human and Preclinical Models

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

The good, the bad and the autophagosome: exploring unanswered questions of autophagy-dependent cell death

(2019) Jurgen Kriel et al.   CELL DEATH AND DIFFERENTIATION

Posthemorrhagic hydrocephalus development after germinal matrix hemorrhage: Established mechanisms and proposed pathways

(2019) Damon Klebe et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Pre-administration of luteoline attenuates neonatal sevoflurane-induced neurotoxicity in mice

(2019) Yang Wang et al.   ACTA HISTOCHEMICA

Neuroinflammation in the Developing Brain

(2019) Olivier Baud et al.   ANESTHESIA AND ANALGESIA

Neurodevelopmental Follow-up of Preterm Infants

(2019) Elisabeth C. McGowan et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Assessing therapeutic response non-invasively in a neonatal rat model of acute inflammatory white matter injury using high-field MRI

(2019) Wyston C. Pierre et al.   BRAIN BEHAVIOR AND IMMUNITY

Sevoflurane induces cognitive impairment in young mice via autophagy

(2019) Xiaoning Wang et al.   PLoS One

Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human

(2019) Helen B. Stolp et al.   Frontiers in Physiology

Treatment thresholds for intervention in posthaemorrhagic ventricular dilation: a randomised controlled trial

(2018) Linda S de Vries et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Altered functional network connectivity in preterm infants: antecedents of cognitive and motor impairments?

(2018) Elveda Gozdas et al.   Brain Structure & Function

Somatosensory function and pain in extremely preterm young adults from the UK EPICure cohort: sex-dependent differences and impact of neonatal surgery

(2018) S.M. Walker et al.   BRITISH JOURNAL OF ANAESTHESIA

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Hypoxia-ischemia and brain injury in infants born preterm

(2018) Nigel Paneth   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus

(2018) Ruth Gussenhoven et al.   Journal of Neuroinflammation

Pretreatment with magnesium sulfate attenuates white matter damage by preventing cell death of developing oligodendrocytes

(2018) Takahiro Seyama et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Nutrient Intake in the First Two Weeks of Life and Brain Growth in Preterm Neonates

(2018) Juliane Schneider et al.   PEDIATRICS

Timing of sepsis is an important risk factor for white matter abnormality in extremely premature infants with sepsis

(2018) Ju Sun Heo et al.   Pediatrics and Neonatology

Caffeine Augments Anesthesia Neurotoxicity in the Fetal Macaque Brain

(2018) Kevin K. Noguchi et al.   Scientific Reports

Association of Histologic Chorioamnionitis With Perinatal Brain Injury and Early Childhood Neurodevelopmental Outcomes Among Preterm Neonates

(2018) Daniel Bierstone et al.   JAMA Pediatrics

Neurodevelopmental Outcomes of Preterm Children at School Age and Beyond

(2018) Anne Synnes et al.   CLINICS IN PERINATOLOGY

Human Umbilical Cord Blood Therapy Protects Cerebral White Matter from Systemic LPS Exposure in Preterm Fetal Sheep

(2018) Madison C.B. Paton et al.   DEVELOPMENTAL NEUROSCIENCE

Estrogen treatment reverses prematurity-induced disruption in cortical interneuron population

(2018) Sanjeet Panda et al.   JOURNAL OF NEUROSCIENCE

Cerebellar injury and impaired function in a rabbit model of maternal inflammation induced neonatal brain injury

(2018) Zhi Zhang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Enhanced autophagy contributes to excitotoxic lesions in a rat model of preterm brain injury

(2018) Céline Descloux et al.   Cell Death & Disease

White matter injury predicts disrupted functional connectivity and microstructure in very preterm born neonates

(2018) Emma G. Duerden et al.   NeuroImage-Clinical

Oxidative Stress as a Primary Risk Factor for Brain Damage in Preterm Newborns

(2018) Isabella Panfoli et al.   Frontiers in Pediatrics

Neuroprotection by Caffeine in Hyperoxia-Induced Neonatal Brain Injury

(2017) Stefanie Endesfelder et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transient Hypoxemia Chronically Disrupts Maturation of Preterm Fetal Ovine Subplate Neuron Arborization and Activity

(2017) Evelyn McClendon et al.   JOURNAL OF NEUROSCIENCE

Fingolimod against endotoxin-induced fetal brain injury in a rat model

(2017) And Yavuz et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Impact of Early Nutritional Intake on Preterm Brain: A Magnetic Resonance Imaging Study

(2017) Lydie Beauport et al.   JOURNAL OF PEDIATRICS

Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood

(2017) Wandert Schaafsma et al.   NEUROBIOLOGY OF DISEASE

Intravenous injection of umbilical cord-derived mesenchymal stromal cells attenuates reactive gliosis and hypomyelination in a neonatal intraventricular hemorrhage model

(2017) Takeo Mukai et al.   NEUROSCIENCE

Caffeine Protects Against Anticonvulsant-Induced Neurotoxicity in the Developing Rat Brain

(2017) Stefanie Endesfelder et al.   NEUROTOXICITY RESEARCH

Term vs. preterm cord blood cells for the prevention of preterm brain injury

(2017) Jingang Li et al.   PEDIATRIC RESEARCH

The Beneficial Effects of Melatonin Administration Following Hypoxia-Ischemia in Preterm Fetal Sheep

(2017) Tamara Yawno et al.   Frontiers in Cellular Neuroscience

Neurodevelopmental outcome at 2 years for preterm children born at 22 to 34 weeks’ gestation in France in 2011: EPIPAGE-2 cohort study

(2017) Véronique Pierrat et al.   BMJ-British Medical Journal

Neurodevelopmental outcome at 2 years for preterm children born at 22 to 34 weeks’ gestation in France in 2011: EPIPAGE-2 cohort study

(2017) Véronique Pierrat et al.   BMJ-British Medical Journal

Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity

(2017) Barbara Schmidt et al.   JAMA Pediatrics

Activation of Autophagy Contributes to Sevoflurane-Induced Neurotoxicity in Fetal Rats

(2017) Xingyue Li et al.   Frontiers in Molecular Neuroscience

Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain

(2017) Kevin D. Broad et al.   PLoS One

Functional Role of Intracellular Calcium Receptor Inositol 1,4,5-Trisphosphate Type 1 in Rat Hippocampus after Neonatal Anoxia

(2017) Juliane Midori Ikebara et al.   PLoS One

Exploring the role of white matter connectivity in cortex maturation

(2017) Cecilia L. Friedrichs-Maeder et al.   PLoS One

Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury

(2016) Cuicui Xie et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Delayed application of the haematopoietic growth factors G-CSF/SCF and FL reduces neonatal excitotoxic brain injury

(2016) Vera Neubauer et al.   BRAIN RESEARCH

Loss of PINK1 inhibits apoptosis by upregulating α-synuclein in inflammation-sensitized hypoxic-ischemic injury in the immature brains

(2016) Jianghu Zhu et al.   BRAIN RESEARCH

Motor and cognitive outcome after specific early lesions of the brain - a systematic review

(2016) Tjitske Hielkema et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Preterm white matter brain injury is prevented by early administration of umbilical cord blood cells

(2016) Jingang Li et al.   EXPERIMENTAL NEUROLOGY

Partial white and grey matter protection with prolonged infusion of recombinant human erythropoietin after asphyxia in preterm fetal sheep

(2016) Guido Wassink et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intranasal surfactant protein D as neuroprotective rescue in a neonatal rat model of periventricular leukomalacia

(2016) Abdullah Kumral et al.   Journal of Maternal-Fetal & Neonatal Medicine

Caffeine combined with sedative/anesthetic drugs triggers widespread neuroapoptosis in a mouse model of prematurity

(2016) Omar Hoseá Cabrera et al.   Journal of Maternal-Fetal & Neonatal Medicine

Intra-amniotic LPS causes acute neuroinflammation in preterm rhesus macaques

(2016) Augusto F. Schmidt et al.   Journal of Neuroinflammation

AMPA-Kainate Receptor Inhibition Promotes Neurologic Recovery in Premature Rabbits with Intraventricular Hemorrhage

(2016) P. Dohare et al.   JOURNAL OF NEUROSCIENCE

Dexmedetomidine Attenuates Neurotoxicity Induced by Prenatal Propofol Exposure

(2016) Jing Li et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway

(2016) Silvia Carloni et al.   JOURNAL OF PINEAL RESEARCH

Relation between clinical risk factors, early cortical changes, and neurodevelopmental outcome in preterm infants

(2016) Karina J. Kersbergen et al.   NEUROIMAGE

Dopamine treatment during acute hypoxia is neuroprotective in the developing sheep brain

(2016) N. Brew et al.   NEUROSCIENCE

Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury

(2016) Daniela Hoeber et al.   Oxidative Medicine and Cellular Longevity

Neurodevelopmental Outcomes After Neonatal Surgery for Major Noncardiac Anomalies

(2016) L. J. Stolwijk et al.   PEDIATRICS

NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol

(2016) Lisa M Askie et al.   BMC Pediatrics

Association between preterm brain injury and exposure to chorioamnionitis during fetal life

(2016) Devasuda Anblagan et al.   Scientific Reports

Evolution of T1 Relaxation, ADC, and Fractional Anisotropy during Early Brain Maturation: A Serial Imaging Study on Preterm Infants

(2015) J. Schneider et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

A Critical Review of Models of Perinatal Infection

(2015) Justin M. Dean et al.   DEVELOPMENTAL NEUROSCIENCE

Preclinical Models of Encephalopathy of Prematurity

(2015) Lauren L. Jantzie et al.   DEVELOPMENTAL NEUROSCIENCE

Cellular Mechanisms of Toll-Like Receptor-3 Activation in the Thalamus Are Associated With White Matter Injury in the Developing Brain

(2015) Regina Vontell et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The role of inflammation in perinatal brain injury

(2015) Henrik Hagberg et al.   Nature Reviews Neurology

Neonatal anoxia in rats: Hippocampal cellular and subcellular changes related to cell death and spatial memory

(2015) S.H. Takada et al.   NEUROSCIENCE

Neuroprotective Effect of Dexmedetomidine on Hyperoxia-Induced Toxicity in the Neonatal Rat Brain

(2015) Marco Sifringer et al.   Oxidative Medicine and Cellular Longevity

A pilot randomized trial of high-dose caffeine therapy in preterm infants

(2015) Christopher McPherson et al.   PEDIATRIC RESEARCH

Subplate in a rat model of preterm hypoxia-ischemia

(2015) Chika Okusa et al.   Annals of Clinical and Translational Neurology

General anaesthetics and the developing brain: an overview

(2014) B. Sinner et al.   ANAESTHESIA

Dying neurons in thalamus of asphyxiated term newborns and rats are autophagic

(2014) Vanessa Ginet et al.   ANNALS OF NEUROLOGY

Involvement of autophagy in hypoxic-excitotoxic neuronal death

(2014) Vanessa Ginet et al.   Autophagy

Postnatal Erythropoietin Mitigates Impaired Cerebral Cortical Development Following Subplate Loss from Prenatal Hypoxia–Ischemia

(2014) Lauren L. Jantzie et al.   CEREBRAL CORTEX

The sigma-1 receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) protects against newborn excitotoxic brain injury by stabilizing the mitochondrial membrane potential in vitro and inhibiting microglial activation in vivo

(2014) Karina Wegleiter et al.   EXPERIMENTAL NEUROLOGY

Minocycline protects the immature white matter against hyperoxia

(2014) Thomas Schmitz et al.   EXPERIMENTAL NEUROLOGY

Extracellular hemoglobin - mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage

(2014) Magnus Gram et al.   Journal of Neuroinflammation

The common antitussive agent dextromethorphan protects against hyperoxia-induced cell death in established in vivo and in vitro models of neonatal brain injury

(2014) A. Posod et al.   NEUROSCIENCE

Brain Injury and Altered Brain Growth in Preterm Infants: Predictors and Prognosis

(2014) H. Kidokoro et al.   PEDIATRICS

Role of Recurrent Hypoxia-Ischemia in Preterm White Matter Injury Severity

(2014) Matthew W. Hagen et al.   PLoS One

Microglia toxicity in preterm brain injury

(2014) Ana A. Baburamani et al.   REPRODUCTIVE TOXICOLOGY

Surgery and Neurodevelopmental Outcome of Very Low-Birth-Weight Infants

(2014) Frank H. Morriss et al.   JAMA Pediatrics

HIP/PAP prevents excitotoxic neuronal death and promotes plasticity

(2014) Parthiv Haldipur et al.   Annals of Clinical and Translational Neurology

Lactoferrin during lactation protects the immature hypoxic-ischemic rat brain

(2014) Yohan van de Looij et al.   Annals of Clinical and Translational Neurology

Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury

(2014) Jennifer D Sokolowski et al.   Acta Neuropathologica Communications

New MR Imaging Assessment Tool to Define Brain Abnormalities in Very Preterm Infants at Term

(2013) H. Kidokoro et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Sevoflurane Anesthesia in Pregnant Mice Induces Neurotoxicity in Fetal and Offspring Mice

(2013) Hui Zheng et al.   ANESTHESIOLOGY

Isoflurane-induced Apoptosis of Neurons and Oligodendrocytes in the Fetal Rhesus Macaque Brain

(2013) Catherine E. Creeley et al.   ANESTHESIOLOGY

Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain

(2013) C. Creeley et al.   BRITISH JOURNAL OF ANAESTHESIA

Developmental Expression of N-Methyl-d-Aspartate (NMDA) Receptor Subunits in Human White and Gray Matter: Potential Mechanism of Increased Vulnerability in the Immature Brain

(2013) Lauren L. Jantzie et al.   CEREBRAL CORTEX

12/15-Lipoxygenase Expression Is Increased in Oligodendrocytes and Microglia of Periventricular Leukomalacia

(2013) Robin L. Haynes et al.   DEVELOPMENTAL NEUROSCIENCE

Maternal Exposure to Lipopolysaccharide Leads to Transient Motor Dysfunction in Neonatal Rats

(2013) Catherine I. Rousset et al.   DEVELOPMENTAL NEUROSCIENCE

Maternal Endotoxin Exposure Results in Abnormal Neuronal Architecture in the Newborn Rabbit

(2013) Bindu Balakrishnan et al.   DEVELOPMENTAL NEUROSCIENCE

Inhaled NO prevents hyperoxia-induced white matter damage in neonatal rats

(2013) Hoa Pham et al.   EXPERIMENTAL NEUROLOGY

Caffeine protects neuronal cells against injury caused by hyperoxia in the immature brain

(2013) Stefanie Endesfelder et al.   FREE RADICAL BIOLOGY AND MEDICINE

Intranasal epidermal growth factor treatment rescues neonatal brain injury

(2013) Joseph Scafidi et al.   NATURE

Abnormal brain maturation in preterm neonates associated with adverse developmental outcomes

(2013) V. Chau et al.   NEUROLOGY

Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats

(2013) L.-W. Fan et al.   NEUROSCIENCE

Definition and quantification of acute inflammatory white matter injury in the immature brain by MRI/MRS at high magnetic field

(2013) Gregory A. Lodygensky et al.   PEDIATRIC RESEARCH

The Effect of Hypothermia Therapy on Cortical Laminar Disruption following Ischemic Injury in Neonatal Mice

(2013) Hiroyuki Kida et al.   PLoS One

Impact of Perinatal Systemic Hypoxic–Ischemic Injury on the Brain of Male Offspring Rats: An Improved Model of Neonatal Hypoxic–Ischemic Encephalopathy in Early Preterm Newborns

(2013) Yuejun Huang et al.   PLoS One

Experimental Modelling of the Consequences of Brief Late Gestation Asphyxia on Newborn Lamb Behaviour and Brain Structure

(2013) Margie Castillo-Melendez et al.   PLoS One

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

(2013) Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple interacting cell death mechanisms in the mediation of excitotoxicity and ischemic brain damage: A challenge for neuroprotection

(2013) Julien Puyal et al.   PROGRESS IN NEUROBIOLOGY

Mesenchymal Stem Cells Prevent Hydrocephalus After Severe Intraventricular Hemorrhage

(2013) So Yoon Ahn et al.   STROKE

Ketamine-induced Neuroapoptosis in the Fetal and Neonatal Rhesus Macaque Brain

(2012) Ansgar M. Brambrink et al.   ANESTHESIOLOGY

Autophagic cell death exists

(2012) Peter G.H. Clarke et al.   Autophagy

The influence of preterm birth on the developing thalamocortical connectome

(2012) Gareth Ball et al.   CORTEX

Erythropoietin Modulates Autophagy Signaling in the Developing Rat Brain in an In Vivo Model of Oxygen-Toxicity

(2012) Ivo Bendix et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity

(2012) Barbara Schmidt   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain

(2012) Lan-Wan Wang et al.   Journal of Neuroinflammation

Microglial Reaction in Axonal Crossroads Is a Hallmark of Noncystic Periventricular White Matter Injury in Very Preterm Infants

(2012) Catherine Verney et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Oligodendrocyte Regeneration after Neonatal Hypoxia Requires FoxO1-Mediated p27Kip1 Expression

(2012) B. Jablonska et al.   JOURNAL OF NEUROSCIENCE

Quantitative MRI in the very preterm brain: Assessing tissue organization and myelination using magnetization transfer, diffusion tensor and T1 imaging

(2012) Revital Nossin-Manor et al.   NEUROIMAGE

The Instrumented Fetal Sheep as a Model of Cerebral White Matter Injury in the Premature Infant

(2012) Stephen A. Back et al.   Neurotherapeutics

Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis

(2012) M Sifringer et al.   Cell Death & Disease

Neonatal Desflurane Exposure Induces More Robust Neuroapoptosis than Do Isoflurane and Sevoflurane and Impairs Working Memory

(2011) Mitsuyoshi Kodama et al.   ANESTHESIOLOGY

Neuronal cell death in neonatal hypoxia-ischemia

(2011) Frances J. Northington et al.   ANNALS OF NEUROLOGY

Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury

(2011) Ylva Carlsson et al.   ANNALS OF NEUROLOGY

Neuron deficit in the white matter and subplate in periventricular leukomalacia

(2011) Hannah C. Kinney et al.   ANNALS OF NEUROLOGY

Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants

(2011) Joshua R. Buser et al.   ANNALS OF NEUROLOGY

Beclin 1-independent autophagy contributes to apoptosis in cortical neurons

(2011) Yulia Grishchuk et al.   Autophagy

Cell proliferation in human ganglionic eminence and suppression after prematurity-associated haemorrhage

(2011) M. R. Del Bigio   BRAIN

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Bone Morphogenetic Protein Inhibition Promotes Neurological Recovery after Intraventricular Hemorrhage

(2011) K. Dummula et al.   JOURNAL OF NEUROSCIENCE

Neurologic Outcomes in Very Preterm Infants Undergoing Surgery

(2011) Peter M. Filan et al.   JOURNAL OF PEDIATRICS

Gray Matter Volume Decrements in Preterm Children With Periventricular Leukomalacia

(2011) Leire Zubiaurre-Elorza et al.   PEDIATRIC RESEARCH

Isoflurane-induced Neuroapoptosis in the Neonatal Rhesus Macaque Brain

(2010) Ansgar M. Brambrink et al.   ANESTHESIOLOGY

Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition

(2010) Govindaiah Vinukonda et al.   BRAIN

Effects of prenatal infection on brain development and behavior: A review of findings from animal models

(2010) Patricia Boksa   BRAIN BEHAVIOR AND IMMUNITY

The Cerebral Cortex Overlying Periventricular Leukomalacia: Analysis of Pyramidal Neurons

(2010) Sarah E. Andiman et al.   BRAIN PATHOLOGY

Role of p75NTR in NMDAR-mediated excitotoxic brain injury in neonatal mice

(2010) Elke Griesmaier et al.   BRAIN RESEARCH

The cannabinoid receptor agonist WIN 55,212-2 reduces the initial cerebral damage after hypoxic–ischemic injury in fetal lambs

(2010) Daniel Alonso-Alconada et al.   BRAIN RESEARCH

Early childhood general anaesthesia exposure and neurocognitive development

(2010) L Sun   BRITISH JOURNAL OF ANAESTHESIA

Autophagy for tissue homeostasis and neuroprotection

(2010) Guillermo Mariño et al.   CURRENT OPINION IN CELL BIOLOGY

Timing of Appearance of Late Oligodendrocyte Progenitors Coincides with Enhanced Susceptibility of Preterm Rabbit Cerebral White Matter to Hypoxia-Ischemia

(2010) Joshua R Buser et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Postnatal erythropoietin treatment mitigates neural cell loss after systemic prenatal hypoxic-ischemic injury

(2010) Marcus Mazur et al.   Journal of Neurosurgery-Pediatrics

Expression of soluble Fas in the cerebrospinal fluid of preterm infants with posthemorrhagic hydrocephalus and cystic white matter damage

(2010) Thomas Schmitz et al.   JOURNAL OF PERINATAL MEDICINE

Neuroprotective effects of NAP against excitotoxic brain damage in the newborn mice: implications for cerebral palsy

(2010) P. Sokolowska et al.   NEUROSCIENCE

76 Efficacy of a Feeding Guideline Based Upon Gastric Emptying

(2010) D Knight et al.   PEDIATRIC RESEARCH

Enhancement of Autophagic Flux after Neonatal Cerebral Hypoxia-Ischemia and Its Region-Specific Relationship to Apoptotic Mechanisms

(2009) Vanessa Ginet et al.   AMERICAN JOURNAL OF PATHOLOGY

Postischemic treatment of neonatal cerebral ischemia should target autophagy

(2009) Julien Puyal et al.   ANNALS OF NEUROLOGY

Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro

(2009) J.M. Dean et al.   BRAIN BEHAVIOR AND IMMUNITY

Astrocytic Demise in the Developing Rat and Human Brain after Hypoxic-Ischemic Damage

(2009) Antoinette Gelot et al.   DEVELOPMENTAL NEUROSCIENCE

High Dose Magnesium Sulfate Exposure Induces Apoptotic Cell Death in the Developing Neonatal Mouse Brain

(2009) William H. Dribben et al.   Neonatology

Protective Effects of Topiramate against Hyperoxic Brain Injury in the Developing Brain

(2009) S. H. Kurul et al.   NEUROPEDIATRICS

The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis

(2009) Kim-Da Destot-Wong et al.   NEUROPHARMACOLOGY

Cerebellar white matter injury following systemic endotoxemia in preterm fetal sheep

(2009) J.M. Dean et al.   NEUROSCIENCE

Thalamic Damage in Periventricular Leukomalacia: Novel Pathologic Observations Relevant to Cognitive Deficits in Survivors of Prematurity

(2009) Poonam Ligam et al.   PEDIATRIC RESEARCH

Oxidative-Nitrosative Stress in a Rabbit Pup Model of Germinal Matrix Hemorrhage

(2009) Muhammad T. Zia et al.   STROKE

Subanesthetic Doses of Propofol Induce Neuroapoptosis in the Infant Mouse Brain

(2008) Davide Cattano et al.   ANESTHESIA AND ANALGESIA

A critical role for Fas/CD-95 dependent signaling pathways in the pathogenesis of hyperoxia-induced brain injury

(2008) Mark Dzietko et al.   ANNALS OF NEUROLOGY

Erythropoietin protects the developing brain from hyperoxia-induced cell death and proteome changes

(2008) Angela M. Kaindl et al.   ANNALS OF NEUROLOGY

Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury

(2008) Kristen N. Segovia et al.   ANNALS OF NEUROLOGY

Primary cortical folding in the human newborn: an early marker of later functional development

(2008) J. Dubois et al.   BRAIN

Hyperoxic exposure leads to cell death in the developing brain

(2008) Uluç Yiş et al.   BRAIN & DEVELOPMENT

RESEARCH ARTICLE: Myelin Abnormalities without Oligodendrocyte Loss in Periventricular Leukomalacia

(2008) Saraid S. Billiards et al.   BRAIN PATHOLOGY

Limited role of the c-Jun N-terminal kinase pathway in a neonatal rat model of cerebral hypoxia-ischemia

(2008) Vanessa Ginet et al.   JOURNAL OF NEUROCHEMISTRY

Adverse Neurodevelopment in Preterm Infants with Postnatal Sepsis or Necrotizing Enterocolitis is Mediated by White Matter Abnormalities on Magnetic Resonance Imaging at Term

(2008) Divyen K. Shah et al.   JOURNAL OF PEDIATRICS

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effect of erythropoietin on oxygen-induced brain injury in the newborn rat

(2008) Uluç Yiş et al.   NEUROSCIENCE LETTERS

Diffuse Axonal Injury in Periventricular Leukomalacia as Determined by Apoptotic Marker Fractin

(2008) Robin L Haynes et al.   PEDIATRIC RESEARCH

Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits

(2008) R. H. Fontaine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Acute Brain Injuries and Neurobehavioral Profiles in a Rabbit Model of Germinal Matrix Hemorrhage

(2008) Paraskevi Georgiadis et al.   STROKE