Impact of Adaptive Thermogenesis in Mice on the Treatment of Obesity

Mechanisms of Impaired Brown Adipose Tissue Recruitment in Obesity

(2019) Martín Alcalá et al.   Frontiers in Physiology

Tea Seed Oil Prevents Obesity, Reduces Physical Fatigue, and Improves Exercise Performance in High-Fat-Diet-Induced Obese Ovariectomized Mice

(2019) Yu-Tang Tung et al.   MOLECULES

Ion Channels and Thermosensitivity: TRP, TREK, or Both?

(2019) J. Antonio Lamas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fluvastatin Sodium Ameliorates Obesity through Brown Fat Activation

(2019) Na Yin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rosiglitazone Enhances Browning Adipocytes in Association with MAPK and PI3-K Pathways During the Differentiation of Telomerase-Transformed Mesenchymal Stromal Cells into Adipocytes

(2019) Abeer Fayyad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ginger prevents obesity through regulation of energy metabolism and activation of browning in high-fat diet-induced obese mice

(2019) Jing Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Calcium Supplementation Alleviates High-Fat Diet-Induced Estrous Cycle Irregularity and Subfertility Associated with Concomitantly Enhanced Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

(2019) Fenglin Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Probing the coding logic of thermosensation using spinal cord calcium imaging

(2019) Chen Ran et al.   EXPERIMENTAL NEUROLOGY

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

(2019) Atul S. Deshmukh et al.   Cell Metabolism

New approaches targeting brown adipose tissue transplantation as a therapy in obesity

(2018) M. Carmen Soler-Vázquez et al.   BIOCHEMICAL PHARMACOLOGY

Effects of exercise on brown and beige adipocytes

(2018) Revati S. Dewal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Of mice and men - environmental temperature, body temperature, and treatment of obesity

(2018) Marc L. Reitman   FEBS LETTERS

Mitochondrial dysfunction in obesity

(2018) Aline Haas de Mello et al.   LIFE SCIENCES

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

(2018) Alexander Bartelt et al.   NATURE MEDICINE

The Common and Distinct Features of Brown and Beige Adipocytes

(2018) Kenji Ikeda et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

CXCL14, a Brown Adipokine that Mediates Brown-Fat-to-Macrophage Communication in Thermogenic Adaptation

(2018) Rubén Cereijo et al.   Cell Metabolism

Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine

(2018) Osamu Hashimoto et al.   Cell Reports

Exercise Induces White Adipose Tissue Browning Across the Weight Spectrum in Humans

(2018) Berenice Otero-Díaz et al.   Frontiers in Physiology

Warming the mouse to model human diseases

(2017) Kirthana Ganeshan et al.   Nature Reviews Endocrinology

Health Effects of Overweight and Obesity in 195 Countries over 25 Years

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

(2017) Alexander Bartelt et al.   Nature Communications

BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue

(2017) Jenny M. Hoffmann et al.   Cell Reports

The lateral parabrachial nucleus, but not the thalamus, mediates thermosensory pathways for behavioural thermoregulation

(2017) Takaki Yahiro et al.   Scientific Reports

Warm-Sensitive Neurons that Control Body Temperature

(2016) Chan Lek Tan et al.   CELL

Cold-induced thermogenesis in humans

(2016) R J Brychta et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Epigenome-wide association study of body mass index and the adverse outcomes of adiposity

(2016) Simone Wahl et al.   NATURE

Prdm4 induction by the small molecule butein promotes white adipose tissue browning

(2016) No-Joon Song et al.   Nature Chemical Biology

Brown adipose tissue as a secretory organ

(2016) Francesc Villarroya et al.   Nature Reviews Endocrinology

β3-Adrenoceptor agonists for overactive bladder syndrome: Role of translational pharmacology in a repositioning clinical drug development project

(2016) Martin C. Michel et al.   PHARMACOLOGY & THERAPEUTICS

Recent advances in thermoregulation

(2015) Etain A. Tansey et al.   ADVANCES IN PHYSIOLOGY EDUCATION

Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist

(2015) Aaron M. Cypess et al.   Cell Metabolism

Variations in the implementation of acute care surgery

(2015) Heena P. Santry et al.   Journal of Trauma and Acute Care Surgery

Serum FGF21 levels are associated with brown adipose tissue activity in humans

(2015) Mark J.W. Hanssen et al.   Scientific Reports

Variations in the implementation of acute care surgery

(2015) Heena P. Santry et al.   Journal of Trauma and Acute Care Surgery

Integration of body temperature into the analysis of energy expenditure in the mouse

(2015) Gustavo Abreu-Vieira et al.   Molecular Metabolism

Fatty acid metabolism and the basis of brown adipose tissue function

(2015) María Calderon-Dominguez et al.   Adipocyte

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis

(2014) Rajesh R. Rao et al.   CELL

The Browning of White Adipose Tissue: Some Burning Issues

(2014) Jan Nedergaard et al.   Cell Metabolism

Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

(2014) Paul Lee et al.   Cell Metabolism

β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors

(2014) Lee D. Roberts et al.   Cell Metabolism

Browning of White Adipose Cells by Intermediate Metabolites: An Adaptive Mechanism to Alleviate Redox Pressure

(2014) A. Carriere et al.   DIABETES

BMP7 Drives Human Adipogenic Stem Cells into Metabolically Active Beige Adipocytes

(2014) Meshail Okla et al.   LIPIDS

Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

(2014) Thorsten Gnad et al.   NATURE

Fighting in the home cage: Agonistic encounters and effects on neurobiological markers within the social decision-making network of house mice (Mus musculus)

(2014) Gian D. Greenberg et al.   NEUROSCIENCE LETTERS

Translating Animal Model Research: Does It Matter That Our Rodents Are Cold?

(2014) Shane K. Maloney et al.   PHYSIOLOGY

Effects of Housing Density in Five Inbred Strains of Mice

(2014) Judith L. Morgan et al.   PLoS One

Berberine activates thermogenesis in white and brown adipose tissue

(2014) Zhiguo Zhang et al.   Nature Communications

Beyond the Sympathetic Tone: The New Brown Fat Activators

(2013) Francesc Villarroya et al.   Cell Metabolism

Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding

(2013) M. K. Montgomery et al.   DIABETOLOGIA

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

A Sensory-Labeled Line for Cold: TRPM8-Expressing Sensory Neurons Define the Cellular Basis for Cold, Cold Pain, and Cooling-Mediated Analgesia

(2013) W. M. Knowlton et al.   JOURNAL OF NEUROSCIENCE

Reducing Mouse Anxiety during Handling: Effect of Experience with Handling Tunnels

(2013) Kelly Gouveia et al.   PLoS One

City-Scale Expansion of Human Thermoregulatory Costs

(2013) Richard W. Hill et al.   PLoS One

Effects of Dominant/Subordinate Social Status on Formalin-Induced Pain and Changes in Serum Proinflammatory Cytokine Concentrations in Mice

(2013) Marjan Aghajani et al.   PLoS One

Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature

(2013) K. M. Kokolus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

(2012) Andrew J. Whittle et al.   CELL

Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria

(2012) Andriy Fedorenko et al.   CELL

Physiological effects of housing density on C57BL/6J mice over a 9-month period1

(2012) B. Paigen et al.   JOURNAL OF ANIMAL SCIENCE

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

(2012) Marica Bordicchia et al.   JOURNAL OF CLINICAL INVESTIGATION

Unstressing intemperate models: how cold stress undermines mouse modeling

(2012) Christopher L. Karp   JOURNAL OF EXPERIMENTAL MEDICINE

Thermal physiology of laboratory mice: Defining thermoneutrality

(2012) C.J. Gordon   JOURNAL OF THERMAL BIOLOGY

Central circuitries for body temperature regulation and fever

(2011) Kazuhiro Nakamura   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The evolution of endothermy in Cenozoic mammals: a plesiomorphic-apomorphic continuum

(2011) Barry Gordon Lovegrove   BIOLOGICAL REVIEWS

Genetic Defect in Phospholipase C 1 Protects Mice From Obesity by Regulating Thermogenesis and Adipogenesis

(2011) M. Hirata et al.   DIABETES

Disruption of Thyroid Hormone Activation in Type 2 Deiodinase Knockout Mice Causes Obesity With Glucose Intolerance and Liver Steatosis Only at Thermoneutrality

(2011) M. Castillo et al.   DIABETES

Sensing hot and cold with TRP channels

(2011) William C. Wetsel   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat

(2011) Elayne Hondares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of torpor: Mimicking natural metabolic suppression for biomedical applications

(2011) Hjalmar R. Bouma et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Brown adipose tissue activity controls triglyceride clearance

(2011) Alexander Bartelt et al.   NATURE MEDICINE

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

Hepatic FGF21 Expression Is Induced at Birth via PPARα in Response to Milk Intake and Contributes to Thermogenic Activation of Neonatal Brown Fat

(2010) Elayne Hondares et al.   Cell Metabolism

Behavioral thermoregulation in mammals: a review

(2010) Jeremy Terrien   Frontiers in Bioscience-Landmark

Central neural pathways for thermoregulation

(2010) Shaun et al.   Frontiers in Bioscience-Landmark

Phenotyping small animals as models for the human metabolic syndrome: thermoneutrality matters

(2010) J M Overton   INTERNATIONAL JOURNAL OF OBESITY

Nonshivering thermogenesis and its adequate measurement in metabolic studies

(2010) B. Cannon et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Proteomic Analysis for Antiobesity Potential of Capsaicin on White Adipose Tissue in Rats Fed with a High Fat Diet

(2010) Jeong In Joo et al.   JOURNAL OF PROTEOME RESEARCH

"Control" laboratory rodents are metabolically morbid: Why it matters

(2010) B. Martin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue

(2009) Maria Cristina Zingaretti et al.   FASEB JOURNAL

The circadian rhythm of body temperature

(2009) Roberto Refinetti   Frontiers in Bioscience-Landmark

Skin-specific Deletion of Stearoyl-CoA Desaturase-1 Alters Skin Lipid Composition and Protects Mice from High Fat Diet-induced Obesity

(2009) Harini Sampath et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Individual housing of mice — Impact on behaviour and stress responses

(2009) Saskia S. Arndt et al.   PHYSIOLOGY & BEHAVIOR

Lean Phenotype and Resistance to Diet-Induced Obesity in Vitamin D Receptor Knockout Mice Correlates with Induction of Uncoupling Protein-1 in White Adipose Tissue

(2008) Carmen J. Narvaez et al.   ENDOCRINOLOGY

Mutations in ligands and receptors of the leptin–melanocortin pathway that lead to obesity

(2008) I Sadaf Farooqi et al.   Nature clinical practice. Endocrinology & metabolism