Translating Animal Model Research: Does It Matter That Our Rodents Are Cold?

Cell physiology: The changing colour of fat

(2014) Brian Owens   NATURE

BMP7 Activates Brown Adipose Tissue and Reduces Diet-Induced Obesity Only at Subthermoneutrality

(2013) Mariëtte R. Boon et al.   PLoS One

Lipopolysaccharide-Induced Neuronal Activation in the Paraventricular and Dorsomedial Hypothalamus Depends on Ambient Temperature

(2013) Samuel P. Wanner et al.   PLoS One

City-Scale Expansion of Human Thermoregulatory Costs

(2013) Richard W. Hill et al.   PLoS One

Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature

(2013) K. M. Kokolus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermoneutrality modifies the impact of hypoxia on lipid metabolism

(2012) Jonathan C. Jun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Unstressing intemperate models: how cold stress undermines mouse modeling

(2012) Christopher L. Karp   JOURNAL OF EXPERIMENTAL MEDICINE

Thermal physiology of laboratory mice: Defining thermoneutrality

(2012) C.J. Gordon   JOURNAL OF THERMAL BIOLOGY

GH and IGF1: Roles in Energy Metabolism of Long-Living GH Mutant Mice

(2012) H. M. Brown-Borg et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The mammalian gene function resource: the international knockout mouse consortium

(2012) Allan Bradley et al.   MAMMALIAN GENOME

Acutely Decreased Thermoregulatory Energy Expenditure or Decreased Activity Energy Expenditure Both Acutely Reduce Food Intake in Mice

(2012) Karl J. Kaiyala et al.   PLoS One

Effects of Ambient Temperature on Sleep and Cardiovascular Regulation in Mice: The Role of Hypocretin/Orexin Neurons

(2012) Viviana Lo Martire et al.   PLoS One

Not so hot: Optimal housing temperatures for mice to mimic the thermal environment of humans

(2012) John R. Speakman et al.   Molecular Metabolism

Disruption of Thyroid Hormone Activation in Type 2 Deiodinase Knockout Mice Causes Obesity With Glucose Intolerance and Liver Steatosis Only at Thermoneutrality

(2011) M. Castillo et al.   DIABETES

Could increased time spent in a thermal comfort zone contribute to population increases in obesity?

(2011) F. Johnson et al.   Obesity Reviews

Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice

(2010) Carola W. Meyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

What effect will a few degrees of climate change have on human heat balance? Implications for human activity

(2010) Shane K. Maloney et al.   INTERNATIONAL JOURNAL OF BIOMETEOROLOGY

Phenotyping small animals as models for the human metabolic syndrome: thermoneutrality matters

(2010) J M Overton   INTERNATIONAL JOURNAL OF OBESITY

Nonshivering thermogenesis and its adequate measurement in metabolic studies

(2010) B. Cannon et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

A general basis for quarter-power scaling in animals

(2010) J. R. Banavar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why We Should Put Clothes on Mice

(2009) Irfan J. Lodhi et al.   Cell Metabolism

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

The effect of environmental temperature on the production of ultrasounds by isolated non-handled albino mouse pups

(2009) Eyo E. Okon   JOURNAL OF ZOOLOGY

Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality

(2008) S. J. Swoap et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A warmer ambient temperature increases the passage of interleukin-1β into the brains of old rats

(2008) Jessica B. Buchanan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Some like it hot: Mouse temperature preferences in laboratory housing

(2008) Brianna N. Gaskill et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Air-conditioning and the ‘homogenization’ of people and built environments

(2008) Stephen Healy   BUILDING RESEARCH AND INFORMATION

Ventricular arrhythmogenesis: Insights from murine models

(2008) Ian N. Sabir et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY