LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells

Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium

(2019) Shruti Rawal et al.   Cardiovascular Diabetology

Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes

(2019) Estel Solsona-Vilarrasa et al.   Redox Biology

Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in Müller Glial cells

(2018) Virginia Actis Dato et al.   BIOCHEMICAL JOURNAL

The Role of Low-Density Lipoprotein Receptor-Related Protein 1 in Lipid Metabolism, Glucose Homeostasis and Inflammation

(2018) Virginia Actis Dato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of Histone Deacetylases Induces K+ Channel Remodeling and Action Potential Prolongation in HL-1 Atrial Cardiomyocytes

(2018) Patrick Lugenbiel et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Muscle and adipose tissue insulin resistance: malady without mechanism?

(2018) Daniel J. Fazakerley et al.   JOURNAL OF LIPID RESEARCH

The P2Y 2 receptor mediates uptake of matrix-retained and aggregated low density lipoprotein in primary vascular smooth muscle cells

(2016) Tixieanna Dissmore et al.   ATHEROSCLEROSIS

Insulin Signaling and Heart Failure

(2016) Christian Riehle et al.   CIRCULATION RESEARCH

Glucagon-like peptide-1 regulates calcium homeostasis and electrophysiological activities of HL-1 cardiomyocytes

(2016) Jen-Hung Huang et al.   PEPTIDES

Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis

(2016) Yinyuan Ding et al.   EBioMedicine

Clusterin/apolipoprotein J binds to aggregated LDL in human plasma and plays a protective role against LDL aggregation

(2015) Maria Martínez-Bujidos et al.   FASEB JOURNAL

Neuronal LRP1 Regulates Glucose Metabolism and Insulin Signaling in the Brain

(2015) C.-C. Liu et al.   JOURNAL OF NEUROSCIENCE

Lipid-Overloaded Enlarged Adipocytes Provoke Insulin Resistance Independent of Inflammation

(2015) Jong In Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Genetic obesity alters recruitment of TANK-binding kinase 1 and AKT into hypothalamic lipid rafts domains

(2015) Ilse Delint-Ramirez et al.   NEUROCHEMISTRY INTERNATIONAL

Molecular mechanisms of diabetic cardiomyopathy

(2014) Heiko Bugger et al.   DIABETOLOGIA

Cardiomyocyte intracellular cholesteryl ester accumulation promotes tropoelastin physical alteration and degradation

(2014) Valerie Samouillan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Inverse relationship between raft LRP1 localization and non-raft ERK1,2/MMP9 activation in idiopathic dilated cardiomyopathy: Potential impact in ventricular remodeling

(2014) Santiago Roura et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Lipopolysaccharide downregulates CD91/low-density lipoprotein receptor-related protein 1 expression through SREBP-1 overexpression in human macrophages

(2013) P. Costales et al.   ATHEROSCLEROSIS

Ectopic lipid storage and insulin resistance: a harmful relationship

(2013) J. Borén et al.   JOURNAL OF INTERNAL MEDICINE

The SLC2 (GLUT) family of membrane transporters

(2013) Mike Mueckler et al.   MOLECULAR ASPECTS OF MEDICINE

Regulation of Glucose Transporter Translocation in Health and Diabetes

(2012) Jonathan S. Bogan   Annual Review of Biochemistry

Aggregated Low-Density Lipoprotein Induces LRP1 Stabilization Through E3 Ubiquitin Ligase CHFR Downregulation in Human Vascular Smooth Muscle Cells

(2012) Roi Cal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Low-density lipoprotein receptor-related protein 1 mediates hypoxia-induced very low density lipoprotein-cholesteryl ester uptake and accumulation in cardiomyocytes

(2012) Roi Cal et al.   CARDIOVASCULAR RESEARCH

Regulation of glucose transport by insulin: traffic control of GLUT4

(2012) Dara Leto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sphingolipids, Lipotoxic Cardiomyopathy, and Cardiac Failure

(2012) Tae-Sik Park et al.   Heart Failure Clinics

Selective role of sterol regulatory element binding protein isoforms in aggregated LDL-induced vascular low density lipoprotein receptor-related protein-1 expression

(2010) P. Costales et al.   ATHEROSCLEROSIS

Biogenesis and regulation of insulin-responsive vesicles containing GLUT4

(2010) Jonathan S Bogan et al.   CURRENT OPINION IN CELL BIOLOGY

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

(2009) Mark P. Jedrychowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

(2008) Alexander Laatsch et al.   ATHEROSCLEROSIS

Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome

(2008) Heiko Bugger et al.   CLINICAL SCIENCE

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS