The Emerging Roles of Fox Family Transcription Factors in Chromosome Replication, Organization, and Genome Stability

Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling

(2019) Javier Garzón et al.   Cell Reports

Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

(2019) Haiyang Zhang et al.   eLife

Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase

(2019) Michael R. Wasserman et al.   CELL

An explanation for origin unwinding in eukaryotes

(2019) Lance D Langston et al.   eLife

Control of DNA replication timing in the 3D genome

(2019) Claire Marchal et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats

(2019) Xiaoli Li et al.   PLoS Genetics

Characterization of the dimeric CMG/pre-initiation complex and its transition into DNA replication forks

(2019) Lu Liu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The mechanism of eukaryotic CMG helicase activation

(2018) Max E. Douglas et al.   NATURE

Rif1 prolongs the embryonic S phase at the Drosophila mid-blastula transition

(2018) Charles A. Seller et al.   PLOS BIOLOGY

Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing

(2017) Dingqiang Fang et al.   GENES & DEVELOPMENT

From structure to mechanism—understanding initiation of DNA replication

(2017) Alberto Riera et al.   GENES & DEVELOPMENT

Unique Roles of the Non-identical MCM Subunits in DNA Replication Licensing

(2017) Yuanliang Zhai et al.   MOLECULAR CELL

Form and function of topologically associating genomic domains in budding yeast

(2017) Umut Eser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1

(2017) Robert C. Alver et al.   Cell Reports

Recruitment of Fkh1 to replication origins requires precisely positioned Fkh1/2 binding sites and concurrent assembly of the pre-replicative complex

(2017) Allan Reinapae et al.   PLoS Genetics

Identification of Fkh1 and Fkh2 binding site variants associated with dynamically bound DNA elements including replication origins

(2017) A. Zachary Ostrow et al.   Nucleus

Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks

(2017) Ryan Baxley et al.   Genes

Identification of Fkh1 and Fkh2 binding site variants associated with dynamically bound DNA elements including replication origins

(2017) A. Zachary Ostrow et al.   Nucleus

MCM: one ring to rule them all

(2016) Tom D Deegan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase

(2016) Jared M. Peace et al.   GENOME RESEARCH

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

(2016) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mechanisms Governing DDK Regulation of the Initiation of DNA Replication

(2016) Larasati et al.   Genes

DNA replication origin activation in space and time

(2015) Michalis Fragkos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell-Cycle-Regulated Interaction between Mcm10 and Double Hexameric Mcm2-7 Is Required for Helicase Splitting and Activation during S Phase

(2015) Yun Quan et al.   Cell Reports

FOXM1: An emerging master regulator of DNA damage response and genotoxic agent resistance

(2014) Stefania Zona et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

FOXM1 and androgen receptor co-regulate CDC6 gene transcription and DNA replication in prostate cancer cells

(2014) Youhong Liu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex

(2014) S.-i. Hiraga et al.   GENES & DEVELOPMENT

Topologically associating domains are stable units of replication-timing regulation

(2014) Benjamin D. Pope et al.   NATURE

Mechanism of chromosomal DNA replication initiation and replication fork stabilization in eukaryotes

(2014) LiHong Wu et al.   Science China-Life Sciences

Temporal and spatial regulation of eukaryotic DNA replication: From regulated initiation to genome-scale timing program

(2014) Claire Renard-Guillet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Protein Phosphatase 1 Recruitment by Rif1 Regulates DNA Replication Origin Firing by Counteracting DDK Activity

(2014) Anoushka Davé et al.   Cell Reports

Rif1 Controls DNA Replication Timing in Yeast through the PP1 Phosphatase Glc7

(2014) Stefano Mattarocci et al.   Cell Reports

Genetic and epigenetic determinants of DNA replication origins, position and activation

(2013) Marcel Méchali et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Location, location, location: it's all in the timing for replication origins

(2013) O. M. Aparicio   GENES & DEVELOPMENT

Time to Be Versatile: Regulation of the Replication Timing Program in Budding Yeast

(2013) Kazumasa Yoshida et al.   JOURNAL OF MOLECULAR BIOLOGY

Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment

(2013) Toyoaki Natsume et al.   MOLECULAR CELL

DNA-binding specificity changes in the evolution of forkhead transcription factors

(2013) S. Nakagawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Replication Timing

(2013) N. Rhind et al.   Cold Spring Harbor Perspectives in Biology

Helicase Activation and Establishment of Replication Forks at Chromosomal Origins of Replication

(2013) S. Tanaka et al.   Cold Spring Harbor Perspectives in Biology

Regulating DNA Replication in Eukarya

(2013) K. Siddiqui et al.   Cold Spring Harbor Perspectives in Biology

Forkhead Transcription Factors Establish Origin Timing and Long-Range Clustering in S. cerevisiae

(2012) Simon R.V. Knott et al.   CELL

Replication Timing: The Early Bird Catches the Worm

(2012) Max E. Douglas et al.   CURRENT BIOLOGY

Rif1 regulates the replication timing domains on the human genome

(2012) Satoshi Yamazaki et al.   EMBO JOURNAL

FOXM1: From cancer initiation to progression and treatment

(2011) Chuay-Yeng Koo et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

(2011) Ryan C. Heller et al.   CELL

The p53–p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function

(2011) Pang-Kuo Lo et al.   CELLULAR SIGNALLING

Origin Association of Sld3, Sld7, and Cdc45 Proteins Is a Key Step for Determination of Origin-Firing Timing

(2011) Seiji Tanaka et al.   CURRENT BIOLOGY

Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast

(2011) Davide Mantiero et al.   EMBO JOURNAL

Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells

(2011) Hozefa S. Bandukwala et al.   IMMUNITY

Palmitoylation controls the dynamics of budding-yeast heterochromatin via the telomere-binding protein Rif1

(2011) S. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?

(2010) K. Labib   GENES & DEVELOPMENT

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers

(2010) Celine Lefebvre et al.   Molecular Systems Biology

B-Myb is Critical for Proper DNA Duplication During an Unperturbed S Phase in Mouse Embryonic Stem Cells

(2010) Maëlle Lorvellec et al.   STEM CELLS

Conversion of a Replication Origin to a Silencer through a Pathway Shared by a Forkhead Transcription Factor and an S Phase Cyclin

(2007) Laurieann Casey et al.   MOLECULAR BIOLOGY OF THE CELL