Targeting Melanoma Hypoxia with the Food-Grade Lactic Acid Bacterium Lactococcus Lactis

Nanoparticles conjugated with bacteria targeting tumors for precision imaging and therapy

(2019) Yong Luo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Optoacoustic imaging identifies ovarian cancer using a microenvironment targeted theranostic wormhole mesoporous silica nanoparticle

(2018) Abhilash Samykutty et al.   BIOMATERIALS

Osteopontin-targeted probe detects orthotopic breast cancers using optoacoustic imaging

(2018) A. Samykutty et al.   BIOTECHNIC & HISTOCHEMISTRY

Anti-cancer effect of lactic acid bacteria expressing antioxidant enzymes or IL-10 in a colorectal cancer mouse model

(2017) Silvina del Carmen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hypoxia inducible factor (HIF) in the tumor microenvironment: friend or foe?

(2017) Yanqing Huang et al.   Science China-Life Sciences

Bioengineered and biohybrid bacteria-based systems for drug delivery

(2016) Zeinab Hosseinidoust et al.   ADVANCED DRUG DELIVERY REVIEWS

The Response of Macrophages and Neutrophils to Hypoxia in the Context of Cancer and Other Inflammatory Diseases

(2016) Antje Egners et al.   MEDIATORS OF INFLAMMATION

Hypoxia increases the heterogeneity of melanoma cell populations and affects the response to vemurafenib

(2016) DANIELA PUCCIARELLI et al.   Molecular Medicine Reports

Hypoxia and metabolic adaptation of cancer cells

(2016) K L Eales et al.   Oncogenesis

Acidic pH-Targeted Chitosan-Capped Mesoporous Silica Coated Gold Nanorods Facilitate Detection of Pancreatic Tumors via Multispectral Optoacoustic Tomography

(2016) Matthew R Zeiderman et al.   ACS Biomaterials-Science & Engineering

Acidic pH-Targeted Chitosan-Capped Mesoporous Silica Coated Gold Nanorods Facilitate Detection of Pancreatic Tumors via Multispectral Optoacoustic Tomography

(2016) Matthew R Zeiderman et al.   ACS Biomaterials Science & Engineering

Surface display of glycosylated Tyrosinase related protein-2 (TRP-2) tumour antigen on Lactococcus lactis

(2015) Jeevanathan Kalyanasundram et al.   BMC BIOTECHNOLOGY

Soluble RANKL expression in Lactococcus lactis and investigation of its potential as an oral vaccine adjuvant

(2015) Jeong-In Kim et al.   BMC IMMUNOLOGY

Targeting Acidity in Pancreatic Adenocarcinoma: Multispectral Optoacoustic Tomography Detects pH-Low Insertion Peptide Probes In Vivo

(2015) C. W. Kimbrough et al.   CLINICAL CANCER RESEARCH

Orthotopic pancreatic tumors detected by optoacoustic tomography using Syndecan-1

(2015) Charles W. Kimbrough et al.   JOURNAL OF SURGICAL RESEARCH

Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imaging

(2015) Ingo Stoffels et al.   Science Translational Medicine

Tumor specific liposomes improve detection of pancreatic adenocarcinoma in vivo using optoacoustic tomography

(2015) Wenyuan Yin et al.   JOURNAL OF NANOBIOTECHNOLOGY

Melanoma

(2015) Dirk Schadendorf et al.   Nature Reviews Disease Primers

Secretion of biologically active human interleukin 22 (IL-22) by Lactococcus lactis

(2014) María J. Loera-Arias et al.   BIOTECHNOLOGY LETTERS

Targeted Noninvasive Imaging of EGFR-Expressing Orthotopic Pancreatic Cancer Using Multispectral Optoacoustic Tomography

(2014) S. V. Hudson et al.   CANCER RESEARCH

Hypoxia Signaling and the Metastatic Phenotype

(2014) H. Mujcic et al.   CURRENT MOLECULAR MEDICINE

Protective Effects of Lactococci Strains Delivering Either IL-10 Protein or cDNA in a TNBS-induced Chronic Colitis Model

(2014) Silvina del Carmen et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium

(2014) Erik O. Pettersen et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Enhancement of Ad-CRT/E7-Mediated Antitumor Effect by Preimmunization with L. lactis Expressing HPV-16 E7

(2014) Blanca R. Rangel-Colmenero et al.   VIRAL IMMUNOLOGY

Adenovirus-Mediated FKHRL1/TM Sensitizes Melanoma Cells to Apoptosis Induced by Temozolomide

(2014) Michael E. Egger et al.   Human Gene Therapy Clinical Development

Development of a Stress-Inducible Controlled Expression (SICE) system in Lactococcus lactis for the production and delivery of therapeutic molecules at mucosal surfaces

(2013) Bouasria Benbouziane et al.   JOURNAL OF BIOTECHNOLOGY

The tumor microenvironment at a glance

(2013) F. R. Balkwill et al.   JOURNAL OF CELL SCIENCE

Combining two strategies to improve perfusion and drug delivery in solid tumors

(2013) T. Stylianopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia Induces Phenotypic Plasticity and Therapy Resistance in Melanoma via the Tyrosine Kinase Receptors ROR1 and ROR2

(2013) M. P. O'Connell et al.   Cancer Discovery

In vitro and in vivo characterization of DNA delivery using recombinant Lactococcus lactis expressing a mutated form of L. monocytogenes Internalin A

(2012) Marcela de Azevedo et al.   BMC MICROBIOLOGY

Multispectral Opto-acoustic Tomography (MSOT) of the Brain and Glioblastoma Characterization

(2012) Neal C. Burton et al.   NEUROIMAGE

High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting

(2012) Michelle Cronin et al.   PLoS One

Optical Imaging of Cancer Heterogeneity with Multispectral Optoacoustic Tomography

(2012) Eva Herzog et al.   RADIOLOGY

Mucosal Vaccination and Therapy with Genetically Modified Lactic Acid Bacteria

(2012) Jerry Wells   Annual Review of Food Science and Technology

A Bioluminescent Transposon Reporter-Trap Identifies Tumor-Specific Microenvironment-Induced Promoters in Salmonella for Conditional Bacterial-Based Tumor Therapy

(2012) Kelly Flentie et al.   Cancer Discovery

Antitumor effect of sFlt-1 gene therapy system mediated by Bifidobacterium Infantis on Lewis lung cancer in mice

(2011) H Zhu et al.   CANCER GENE THERAPY

The role of nuclear lamin B1 in cell proliferation and senescence

(2011) T. Shimi et al.   GENES & DEVELOPMENT

Lactococcus lactis as a live vector: Heterologous protein production and DNA delivery systems

(2011) Daniela Santos Pontes et al.   PROTEIN EXPRESSION AND PURIFICATION

Induction and Testing of Hypoxia in Cell Culture

(2011) Danli Wu et al.   Jove-Journal of Visualized Experiments

Targeting solid tumors with non-pathogenic obligate anaerobic bacteria

(2010) Shun’ichiro Taniguchi et al.   CANCER SCIENCE

Efficient secretion of a modified E7 protein from human papilloma virus type-16 by Lactococcus lactis

(2010) D. Quistián-Martínez et al.   LETTERS IN APPLIED MICROBIOLOGY

Decoding Melanoma Metastasis

(2010) William E. Damsky et al.   Cancers

Hypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin

(2009) Barbara Bedogni et al.   Pigment Cell & Melanoma Research