Single-nucleus RNA-seq identifies Huntington disease astrocyte states

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Single-cell transcriptomic analysis of Alzheimer’s disease

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Astrocyte molecular signatures in Huntington’s disease

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Massively parallel single-nucleus RNA-seq with DroNc-seq

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Huntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s disease

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A comparative strategy for single-nucleus and single-cell transcriptomes confirms accuracy in predicted cell-type expression from nuclear RNA

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Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease

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Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons

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Symptom heterogeneity in Huntington's disease correlates with neuronal degeneration in the cerebral cortex

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Common disease signatures from gene expression analysis in Huntington’s disease human blood and brain

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Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

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Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

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A survey of human brain transcriptome diversity at the single cell level

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Multiscale Embedded Gene Co-expression Network Analysis

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RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression

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Phenotypic Heterogeneity and Plasticity of Isocortical and Hippocampal Astrocytes in the Human Brain

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The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

(2014) Xiaoping Tong et al.   NATURE NEUROSCIENCE

MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma

(2014) B. J. Gill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GSVA: gene set variation analysis for microarray and RNA-Seq data

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A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease

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Genomic Analysis of Reactive Astrogliosis

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Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

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Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

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Neuroprotective and neuroregenerative properties of metallothioneins

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In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

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Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

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Proteomic and oxidative stress analysis in human brain samples of Huntington disease

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A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

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