Molecular Insights into miRNA-Driven Resistance to 5-Fluorouracil and Oxaliplatin Chemotherapy: miR-23b Modulates the Epithelial–Mesenchymal Transition of Colorectal Cancer Cells

Retrospective comparison of efficacy and safety of CAPOX and FOLFOX regimens as adjuvant treatment in patients with stage III colon cancer

(2019) Serkan Degirmencioglu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Proteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells

(2019) Poel et al.   Cells

Prognostic value of miRNA-181a/b in colorectal cancer: a meta-analysis

(2018) Xingwei Gu et al.   Biomarkers in Medicine

Dual function of programmed cell death 10 (PDCD10) in drug resistance

(2018) Cagri Urfali-Mamatoglu et al.   BIOMEDICINE & PHARMACOTHERAPY

Significance of Notch and Wnt signaling for chemoresistance of colorectal cancer cells HCT116

(2018) Egle Kukcinaviciute et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The role of microRNAs in 5-FU resistance of colorectal cancer: Possible mechanisms

(2018) Reyhaneh Moradi Marjaneh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA-23a promotes colorectal cancer cell survival by targeting PDK4

(2018) Yi Hui Deng et al.   EXPERIMENTAL CELL RESEARCH

Cytoplasmic p21 Mediates 5-Fluorouracil Resistance by Inhibiting Pro-Apoptotic Chk2

(2018) Arnatchai Maiuthed et al.   Cancers

Downregulation of miR-224 and let-7i contribute to cell survival and chemoresistance in chronic myeloid leukemia cells by regulating ST3GAL IV expression

(2017) Huimin Zhou et al.   GENE

Prognostic value of KRAS codon 13 gene mutation for overall survival in colorectal cancer

(2017) Min Seob Kwak et al.   MEDICINE

Insights into the involvement of noncoding RNAs in 5-fluorouracil drug resistance

(2017) Jun Deng et al.   TUMOR BIOLOGY

Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine

(2017) Maria Jeppesen et al.   PLoS One

Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma

(2016) Marija Ger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

miR clusters target cellular functional complexes by defining their degree of regulatory freedom

(2016) Jörg Haier et al.   CANCER AND METASTASIS REVIEWS

MicroRNAs as Regulators, Biomarkers and Therapeutic Targets in the Drug Resistance of Colorectal Cancer

(2016) Tao Xie et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

miR-17-92 plays an oncogenic role and conveys chemo-resistance to cisplatin in human prostate cancer cells

(2016) PENG ZHOU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes

(2016) Yirong Wang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Dysregulation of MicroRNA-543 expression in colorectal cancer promotes tumor migration and invasion

(2016) Jian Sun et al.   MOLECULAR CARCINOGENESIS

Targeting Epithelial–Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer

(2016) Bowen Du et al.   MOLECULES

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Downregulation of mir-23b in plasma is associated with poor prognosis in patients with colorectal cancer

(2016) Chang-Hua Kou et al.   Oncology Letters

Role of Deficient Mismatch Repair in the Personalized Management of Colorectal Cancer

(2016) Cong-Min Zhang et al.   International Journal of Environmental Research and Public Health

Splicing-dependent expression of microRNAs of mirtron origin in human digestive and excretory system cancer cells

(2016) Stasė Butkytė et al.   Clinical Epigenetics

Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis

(2015) Maude Gabriel et al.   BMC CANCER

MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms

(2015) E B Amankwatia et al.   BRITISH JOURNAL OF CANCER

MicroRNAs predict and modulate responses to chemotherapy in colorectal cancer

(2015) Xin Yu et al.   CELL PROLIFERATION

The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis

(2015) Hui Ling et al.   GUT

The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells

(2015) Michele Cioffi et al.   GUT

MicroRNA-520g Confers Drug Resistance by Regulating p21 Expression in Colorectal Cancer

(2015) Yang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of interleukin-8 (CXCL8) and CXCR2 in acquired chemoresistance of human colorectal carcinoma cells HCT116

(2015) Daiva Dabkeviciene et al.   MEDICAL ONCOLOGY

Tumor-Related Molecular Mechanisms of Oxaliplatin Resistance

(2015) E. Martinez-Balibrea et al.   MOLECULAR CANCER THERAPEUTICS

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding

(2015) Hyo-eun C Bhang et al.   NATURE MEDICINE

Towards a molecular understanding of microRNA-mediated gene silencing

(2015) Stefanie Jonas et al.   NATURE REVIEWS GENETICS

In-depth evaluation of software tools for data-independent acquisition based label-free quantification

(2015) Jörg Kuharev et al.   PROTEOMICS

Hypermethylation of the GABRE miR-452 miR-224 Promoter in Prostate Cancer Predicts Biochemical Recurrence after Radical Prostatectomy

(2014) H. Kristensen et al.   CLINICAL CANCER RESEARCH

miR-27a regulates cisplatin resistance and metastasis by targeting RKIP in human lung adenocarcinoma cells

(2014) Jipeng Li et al.   Molecular Cancer

microRNAs miR-27a and miR-27b Directly Regulate Liver Dihydropyrimidine Dehydrogenase Expression through Two Conserved Binding Sites

(2014) S. M. Offer et al.   MOLECULAR CANCER THERAPEUTICS

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

miR-23a promotes cisplatin chemoresistance and protects against cisplatin-induced apoptosis in tongue squamous cell carcinoma cells through Twist

(2014) FUSEN PENG et al.   ONCOLOGY REPORTS

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

An Efficient Genotyping Method for Genome-modified Animals and Human Cells Generated with CRISPR/Cas9 System

(2014) Xiaoxiao Zhu et al.   Scientific Reports

CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data

(2013) Gabriela Bindea et al.   BIOINFORMATICS

Genome-wide analysis reveals downregulation of miR-379/miR-656 cluster in human cancers

(2013) Saurabh V Laddha et al.   Biology Direct

miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance

(2013) L. Zhang et al.   CANCER RESEARCH

MicroRNA-224 Negatively Regulates p21 Expression During Late Neoplastic Progression in Inflammatory Bowel Disease

(2013) Alexandru V. Olaru et al.   INFLAMMATORY BOWEL DISEASES

VEGF suppresses epithelial-mesenchymal transition by inhibiting the expression of Smad3 and miR-192, a Smad3-dependent microRNA

(2013) JUN-PING HONG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase

(2013) Yunfei Zhou et al.   Molecular Oncology

Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment

(2013) J.B. Kjersem et al.   Molecular Oncology

High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer

(2013) Mads H. Rasmussen et al.   Molecular Oncology

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

(2013) Leif Väremo et al.   NUCLEIC ACIDS RESEARCH

Beyond KRAS mutation status: influence of KRAScopy number status and microRNAs on clinical outcome to cetuximab in metastatic colorectal cancer patients

(2012) Leonie JM Mekenkamp et al.   BMC CANCER

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

(2012) Alexandria M Haslehurst et al.   BMC CANCER

MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms

(2012) Yu Wang et al.   FASEB JOURNAL

Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer

(2012) A. Kreso et al.   SCIENCE

Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT)

(2012) Claude C. Warzecha et al.   SEMINARS IN CANCER BIOLOGY

What is bad in cancer is good in the embryo: Importance of EMT in neural crest development

(2012) Laura Kerosuo et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The regulation of cell-cell adhesion during epithelial-mesenchymal transition, motility and tumor progression

(2012) Grégoire F. Le Bras et al.   Cell Adhesion & Migration

miR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines

(2011) H. Chai et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Underexpression of miR-224 in methotrexate resistant human colon cancer cells

(2011) Núria Mencia et al.   BIOCHEMICAL PHARMACOLOGY

Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer

(2011) Nicole Vincent Jordan et al.   CELL CYCLE

Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis

(2011) Hanshuo Zhang et al.   Nature Communications

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

(2011) Irina M. Shapiro et al.   PLoS Genetics

Slug Confers Resistance to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

(2010) Tzu-Hua Chang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Examination of the expanding pathways for the regulation of p21 expression and activity

(2010) Yong-Sam Jung et al.   CELLULAR SIGNALLING

Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

(2010) Melissa G. Mendez et al.   FASEB JOURNAL

Microsatellite Instability in Colorectal Cancer

(2010) C. Richard Boland et al.   GASTROENTEROLOGY

Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer

(2010) K Vuoriluoto et al.   ONCOGENE

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Collective cell migration in morphogenesis, regeneration and cancer

(2009) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interplay of Cadherin-Mediated Cell Adhesion and Canonical Wnt Signaling

(2009) J. Heuberger et al.   Cold Spring Harbor Perspectives in Biology

FOLFOX and FLOX Regimens for the Adjuvant Treatment of Resected Stage II and III Colon Cancer

(2008) Saima Sharif et al.   CANCER INVESTIGATION