Short and Long Term Clinical and Immunologic Follow up after Bone Marrow Mesenchymal Stromal Cell Therapy in Progressive Multiple Sclerosis—A Phase I Study
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Short and Long Term Clinical and Immunologic Follow up after Bone Marrow Mesenchymal Stromal Cell Therapy in Progressive Multiple Sclerosis—A Phase I Study
Authors
Keywords
-
Journal
Journal of Clinical Medicine
Volume 8, Issue 12, Pages 2102
Publisher
MDPI AG
Online
2019-12-03
DOI
10.3390/jcm8122102
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Managing Risks with Immune Therapies in Multiple Sclerosis
- (2019) Moritz Förster et al. DRUG SAFETY
- MEsenchymal StEm cells for Multiple Sclerosis (MESEMS): a randomized, double blind, cross-over phase I/II clinical trial with autologous mesenchymal stem cells for the therapy of multiple sclerosis
- (2019) Antonio Uccelli et al. Trials
- Mesenchymal Stromal Cell-Based Therapy: New Perspectives and Challenges
- (2019) Mehdi Najar et al. Journal of Clinical Medicine
- The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes
- (2019) Caroline Gavin et al. Frontiers in Immunology
- Contribution of microRNAs to the immunosuppressive function of mesenchymal stem cells
- (2018) Yves-Marie Pers et al. BIOCHIMIE
- Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities
- (2018) Jacques Galipeau et al. Cell Stem Cell
- MSCs—cells with many sides
- (2018) Katarina Le Blanc et al. CYTOTHERAPY
- Phenotypic and functional alterations of myeloid-derived suppressor cells during the disease course of multiple sclerosis
- (2018) Ellen Iacobaeus et al. IMMUNOLOGY AND CELL BIOLOGY
- Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis
- (2018) Neil H. Riordan et al. Journal of Translational Medicine
- A Circadian Rhythm in both Complement Cascade (ComC) Activation and Sphingosine-1-Phosphate (S1P) Levels in Human Peripheral Blood Supports a Role for the ComC–S1P Axis in Circadian Changes in the Number of Stem Cells Circulating in Peripheral Blood
- (2018) Marta Budkowska et al. Stem Cell Reviews and Reports
- Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells
- (2018) Samantha F.H. de Witte et al. STEM CELLS
- A Circadian Rhythm in both Complement Cascade (ComC) Activation and Sphingosine-1-Phosphate (S1P) Levels in Human Peripheral Blood Supports a Role for the ComC–S1P Axis in Circadian Changes in the Number of Stem Cells Circulating in Peripheral Blood
- (2018) Marta Budkowska et al. Stem Cell Reviews and Reports
- Immunomonitoring of MSC-Treated GvHD Patients Reveals Only Moderate Potential for Response Prediction but Indicates Treatment Safety
- (2018) Joni Keto et al. Molecular Therapy-Methods & Clinical Development
- Therapeutic Use of Intrathecal Mesenchymal Stem Cells in patients with Multiple Sclerosis: A Pilot Study with Booster Injection
- (2018) Mohammad Ali Sahraian et al. IMMUNOLOGICAL INVESTIGATIONS
- Dysregulation of Mesenchymal Stromal Cell Antioxidant Responses in Progressive Multiple Sclerosis
- (2018) Juliana Redondo et al. Stem Cells Translational Medicine
- Amelioration of clinical symptoms of patients with refractory rheumatoid arthritis following treatment with autologous bone marrow-derived mesenchymal stem cells: A successful clinical trial in Iran
- (2018) Mohsen Ghoryani et al. BIOMEDICINE & PHARMACOTHERAPY
- Characterization of naïve, memory and effector T cells in progressive multiple sclerosis
- (2017) Birgitte Romme Nielsen et al. JOURNAL OF NEUROIMMUNOLOGY
- Progressive MS trials: Lessons learned
- (2017) Carmen Tur et al. Multiple Sclerosis Journal
- Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis
- (2017) Jeffrey A Cohen et al. Multiple Sclerosis Journal
- Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation
- (2017) Antonio Galleu et al. Science Translational Medicine
- Progressive MS trials: Lessons learned
- (2017) Carmen Tur et al. Multiple Sclerosis Journal
- Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis
- (2017) Jeffrey A Cohen et al. Multiple Sclerosis Journal
- Progressive multiple sclerosis: from pathogenic mechanisms to treatment
- (2016) Jorge Correale et al. BRAIN
- MicroRNAs associated with the pathogenesis of multiple sclerosis
- (2016) Qingrong Huang et al. JOURNAL OF NEUROIMMUNOLOGY
- Disease implication of hyper-Hippo signalling
- (2016) Shu-Ping Wang et al. Open Biology
- Human Mesenchymal Stem Cells Impact Th17 and Th1 Responses Through a Prostaglandin E2 and Myeloid-Dependent Mechanism
- (2016) Ayal Rozenberg et al. Stem Cells Translational Medicine
- Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism
- (2016) Anoop Babu Vasandan et al. Scientific Reports
- Bone Marrow Mesenchymal Stromal Cells Isolated from Multiple Sclerosis Patients have Distinct Gene Expression Profile and Decreased Suppressive Function Compared with Healthy Counterparts
- (2015) Gislane L. V. De Oliveira et al. CELL TRANSPLANTATION
- Safety and biodistribution study of bone marrow–derived mesenchymal stromal cells and mononuclear cells and the impact of the administration route in an intact porcine model
- (2015) Tuomas Mäkelä et al. CYTOTHERAPY
- Therapeutic Potential of Multipotent Mesenchymal Stromal Cells and Their Extracellular Vesicles
- (2015) Nina Heldring et al. HUMAN GENE THERAPY
- DIANA-miRPath v3.0: deciphering microRNA function with experimental support
- (2015) Ioannis S. Vlachos et al. NUCLEIC ACIDS RESEARCH
- Human Bone Marrow-Derived Mesenchymal Stromal Cells Differentially Inhibit Cytokine Production by Peripheral Blood Monocytes Subpopulations and Myeloid Dendritic Cells
- (2015) Paula Laranjeira et al. Stem Cells International
- Autologous hematopoietic SCT normalizes miR-16, -155 and -142-3p expression in multiple sclerosis patients
- (2014) L C M Arruda et al. BONE MARROW TRANSPLANTATION
- Preserved β-Cell Function in Type 1 Diabetes by Mesenchymal Stromal Cells
- (2014) Per-Ola Carlsson et al. DIABETES
- Randomized Placebo-Controlled Phase II Trial of Autologous Mesenchymal Stem Cells in Multiple Sclerosis
- (2014) Sara Llufriu et al. PLoS One
- Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?
- (2013) Fábio G. Teixeira et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Alterations in the Cellular Immune Compartment of Patients Treated with Third-Party Mesenchymal Stromal Cells Following Allogeneic Hematopoietic Stem Cell Transplantation
- (2013) Regina Jitschin et al. STEM CELLS
- Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjogren syndrome
- (2012) J. Xu et al. BLOOD
- Mesenchymal stem cells regulate the proliferation of T cells via the growth-related oncogene/CXC chemokine receptor, CXCR2
- (2012) Yong-Soo Lee et al. CELLULAR IMMUNOLOGY
- Possible induction of acute disseminated encephalomyelitis (ADEM)-like demyelinating illness by intrathecal mesenchymal stem cell injection
- (2012) Nirmeen A. Kishk et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study
- (2012) Peter Connick et al. LANCET NEUROLOGY
- Assessing sample and miRNA profile quality in serum and plasma or other biofluids
- (2012) Thorarinn Blondal et al. METHODS
- Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?
- (2012) Guido Moll et al. STEM CELLS
- Analysis of Tissues Following Mesenchymal Stromal Cell Therapy in Humans Indicates Limited Long-Term Engraftment and No Ectopic Tissue Formation
- (2012) L. von Bahr et al. STEM CELLS
- Autologous Mesenchymal Stem Cell Therapy in Progressive Multiple Sclerosis: An Open Label Study
- (2012) Mandana Mohyeddin Bonab et al. Current Stem Cell Research & Therapy
- Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria
- (2011) Chris H. Polman et al. ANNALS OF NEUROLOGY
- Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing
- (2011) Moïra François et al. CYTOTHERAPY
- Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseases
- (2011) Antonio Uccelli et al. LANCET NEUROLOGY
- Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study
- (2010) J. Liang et al. ANNALS OF THE RHEUMATIC DISEASES
- Safety and Immunological Effects of Mesenchymal Stem Cell Transplantation in Patients With Multiple Sclerosis and Amyotrophic Lateral Sclerosis
- (2010) Dimitrios Karussis et al. ARCHIVES OF NEUROLOGY
- Defining the risks of mesenchymal stromal cell therapy
- (2010) Darwin J. Prockop et al. CYTOTHERAPY
- Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: A pilot study
- (2010) Bassem Yamout et al. JOURNAL OF NEUROIMMUNOLOGY
- Human Mesenchymal Stem Cells Infiltrate the Spinal Cord, Reduce Demyelination, and Localize to White Matter Lesions in Experimental Autoimmune Encephalomyelitis
- (2010) David Gordon et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Characterization of in vitro expanded bone marrow-derived mesenchymal stem cells from patients with multiple sclerosis
- (2010) Elizabeth Mallam et al. Multiple Sclerosis Journal
- Mesenchymal Stem Cell Homing: The Devil Is in the Details
- (2009) Jeffrey M. Karp et al. Cell Stem Cell
- Mechanisms involved in the therapeutic properties of mesenchymal stem cells
- (2009) Lindolfo da Silva Meirelles et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Mesenchymal Stromal Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Inhibiting CD4 Th17 T Cells in a CC Chemokine Ligand 2-Dependent Manner
- (2009) Moutih Rafei et al. JOURNAL OF IMMUNOLOGY
- Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effectin vivo
- (2009) Cristina Lanza et al. JOURNAL OF NEUROCHEMISTRY
- Mesenchymal stem cell-secreted superoxide dismutase promotes cerebellar neuronal survival
- (2009) Kevin Kemp et al. JOURNAL OF NEUROCHEMISTRY
- Mesenchymal Stem Cell Transplantation Reverses Multiorgan Dysfunction in Systemic Lupus Erythematosus Mice and Humans
- (2009) Lingyun Sun et al. STEM CELLS
- Distinct Functions of Autoreactive Memory and Effector CD4+ T Cells in Experimental Autoimmune Encephalomyelitis
- (2008) Wassim Elyaman et al. AMERICAN JOURNAL OF PATHOLOGY
- Neuroprotection and Immunomodulation With Mesenchymal Stem Cells in Chronic Experimental Autoimmune Encephalomyelitis
- (2008) Ibrahim Kassis et al. ARCHIVES OF NEUROLOGY
- Differences in mesenchymal stem cell cytokine profiles between MS patients and healthy donors: Implication for assessment of disease activity and treatment
- (2008) Benedetta Mazzanti et al. JOURNAL OF NEUROIMMUNOLOGY
- Multiple sclerosis
- (2008) Alastair Compston et al. LANCET
- Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
- (2008) Katarina Le Blanc et al. LANCET
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More