Glycan Microarrays as Chemical Tools for Identifying Glycan Recognition by Immune Proteins

Mammalian sugar-binding receptors: known functions and unexplored roles

(2019) Maureen E. Taylor et al.   FEBS Journal

Microbe-focused glycan array screening platform

(2019) Andreas Geissner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza binds phosphorylated glycans from human lung

(2019) Lauren Byrd-Leotis et al.   Science Advances

Breaking the Glyco-Code of HIV Persistence and Immunopathogenesis

(2019) Florent Colomb et al.   Current HIV/AIDS Reports

GLAD: GLycan Array Dashboard, a visual analytics tool for glycan microarrays

(2019) Akul Y Mehta et al.   BIOINFORMATICS

CDG and immune response: From bedside to bench and back

(2019) Carlota Pascoal et al.   JOURNAL OF INHERITED METABOLIC DISEASE

IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure

(2019) Lenette L. Lu et al.   NATURE MEDICINE

Next-Generation Glycan Microarray Enabled by DNA-Coded Glycan Library and Next-Generation Sequencing Technology

(2019) Maomao Yan et al.   ANALYTICAL CHEMISTRY

Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

(2019) Heng-Huan Lee et al.   CANCER CELL

“Stuck on sugars – how carbohydrates regulate cell adhesion, recognition, and signaling”

(2019) Richard D. Cummings   GLYCOCONJUGATE JOURNAL

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

(2019) Yoshiki Narimatsu et al.   MOLECULAR CELL

A Tumor-Selective Monoclonal Antibody from Immunization with a Tumor-Associated Mucin Glycopeptide

(2019) Kevin R. Trabbic et al.   Scientific Reports

Sialic acid–binding immunoglobulin-like lectins (Siglecs) detect self-associated molecular patterns to regulate immune responses

(2019) Heinz Läubli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Antigenic pressure on H3N2 influenza drift strains imposes constraints on binding to sialylated receptors, but not phosphorylated glycans

(2019) Lauren Byrd-Leotis et al.   JOURNAL OF VIROLOGY

The Sweet-Side of Leukocytes: Galectins as Master Regulators of Neutrophil Function

(2019) Brian S. Robinson et al.   Frontiers in Immunology

Novel Reversible Fluorescent Glycan Linker for Functional Glycomics

(2019) Mohui Wei et al.   BIOCONJUGATE CHEMISTRY

Evolution of Alternative Adaptive Immune Systems in Vertebrates

(2018) Thomas Boehm et al.   Annual Review of Immunology

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1

(2018) Chia-Wei Li et al.   CANCER CELL

Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment

(2018) María T. Elola et al.   CELLULAR IMMUNOLOGY

Siglecs: A journey through the evolution of sialic acid-binding immunoglobulin-type lectins

(2018) Kim F. Bornhöfft et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Structural and Molecular Characterization of the Hemagglutinin from the Fifth Epidemic Wave A(H7N9) Influenza Viruses

(2018) Hua Yang et al.   JOURNAL OF VIROLOGY

Glycan Binding Specificity and Mechanism of Human and Porcine P[6]/P[19] Rotavirus VP8*s

(2018) Xiaoman Sun et al.   JOURNAL OF VIROLOGY

Human Group C Rotavirus VP8*s Recognize Type A Histo-Blood Group Antigens as Ligands

(2018) Xiaoman Sun et al.   JOURNAL OF VIROLOGY

The Role of Galectins as Modulators of Metabolism and Inflammation

(2018) Monica Fengsrud Brinchmann et al.   MEDIATORS OF INFLAMMATION

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

(2018) Sharad Purohit et al.   Nature Communications

The neoglycolipid (NGL) technology-based microarrays and future prospects

(2018) Zhen Li et al.   FEBS LETTERS

The GAGOme: a cell-based library of displayed glycosaminoglycans

(2018) Yen-Hsi Chen et al.   NATURE METHODS

Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy

(2018) Lin Liu et al.   Nature Chemistry

Structure–function analyses of a pertussis-like toxin from pathogenicEscherichia colireveal a distinct mechanism of inhibition of trimeric G-proteins

(2017) Dene R. Littler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-Glycome Beam Search Arrays for Carbohydrate Ligand Discovery

(2017) Zhen Li et al.   MOLECULAR & CELLULAR PROTEOMICS

Leucine-rich-repeat-containing variable lymphocyte receptors as modules to target plant-expressed proteins

(2017) André C. Velásquez et al.   Plant Methods

Natural polyreactive IgA antibodies coat the intestinal microbiota

(2017) Jeffrey J. Bunker et al.   SCIENCE

Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates

(2017) Bernard C. Collins et al.   STRUCTURE

Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells

(2017) Masahiro Okada et al.   Cell Reports

Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and In Vitro Efficacy Analysis

(2017) Swetha Tati et al.   NEOPLASIA

Galectins and Immune Responses—Just How Do They Do Those Things They Do?

(2016) Sandra Thiemann et al.   Annual Review of Immunology

Diverse molecular recognition properties of blood group A binding monoclonal antibodies

(2016) Jeffrey C Gildersleeve et al.   GLYCOBIOLOGY

Galectins are human milk glycan receptors

(2016) Alexander J Noll et al.   GLYCOBIOLOGY

Identification of Antigenic Glycans from Schistosoma mansoni by Using a Shotgun Egg Glycan Microarray

(2016) Megan L. Mickum et al.   INFECTION AND IMMUNITY

B-cell–independent sialylation of IgG

(2016) Mark B. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Factors Affecting Anti-Glycan IgG and IgM Repertoires in Human Serum

(2016) Saddam M. Muthana et al.   Scientific Reports

The chromosomal nature of LT-II enterotoxins solved: a lambdoid prophage encodes both LT-II and one of two novel pertussis-toxin-like toxin family members in type II enterotoxigenicEscherichia coli

(2016) Michael G. Jobling   Pathogens and Disease

The lectin-like protein 1 in Lactobacillus rhamnosus GR-1 mediates tissue-specific adherence to vaginal epithelium and inhibits urogenital pathogens

(2016) Mariya I. Petrova et al.   Scientific Reports

Intact Reducing Glycan Promotes the Specific Immune Response to Lacto-N-neotetraose-BSA Neoglycoconjugates

(2015) Nina S. Prasanphanich et al.   BIOCONJUGATE CHEMISTRY

Determination of receptor specificities for whole influenza viruses using multivalent glycan arrays

(2015) Mia L. Huang et al.   CHEMICAL COMMUNICATIONS

Monoclonal Antibodies Targeting LecLex-Related Glycans with Potent Antitumor Activity

(2015) J. X. Chua et al.   CLINICAL CANCER RESEARCH

Glycan microarrays of fluorescently-tagged natural glycans

(2015) Xuezheng Song et al.   GLYCOCONJUGATE JOURNAL

Development of a Schistosoma mansoni shotgun O-glycan microarray and application to the discovery of new antigenic schistosome glycan motifs

(2015) Angela van Diepen et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites

(2015) C. Schneider et al.   Science Translational Medicine

Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus

(2015) Liya Hu et al.   Nature Communications

The Challenge and Promise of Glycomics

(2014) Richard D. Cummings et al.   CHEMISTRY & BIOLOGY

The neoglycolipid (NGL)-based oligosaccharide microarray system poised to decipher the meta-glycome

(2014) Angelina S Palma et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

DNA directed immobilization glycocluster array: applications and perspectives

(2014) Yann Chevolot et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chemistry of natural glycan microarrays

(2014) Xuezheng Song et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Differential expression of anti-glycan antibodies in schistosome-infected humans, rhesus monkeys and mice

(2014) A. E. Luyai et al.   GLYCOBIOLOGY

Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers

(2014) Emilia Falkowska et al.   IMMUNITY

Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes

(2014) Motohiro Nonaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbohydrate Sequence of the Prostate Cancer-associated Antigen F77 Assigned by a MucinO-Glycome Designer Array

(2014) Chao Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Characterization by Multistage Mass Spectrometry (MSn) of Human Milk Glycans Recognized by Human Rotaviruses

(2014) David J. Ashline et al.   MOLECULAR & CELLULAR PROTEOMICS

Human Milk Contains Novel Glycans That Are Potential Decoy Receptors for Neonatal Rotaviruses

(2014) Ying Yu et al.   MOLECULAR & CELLULAR PROTEOMICS

Shotgun glycomics of pig lung identifies natural endogenous receptors for influenza viruses

(2014) L. Byrd-Leotis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycan arrays containing synthetic Clostridium difficile lipoteichoic acid oligomers as tools toward a carbohydrate vaccine

(2013) Christopher E. Martin et al.   CHEMICAL COMMUNICATIONS

Presentation, presentation, presentation! Molecular-level insight into linker effects on glycan array screening data

(2013) O. C. Grant et al.   GLYCOBIOLOGY

Development and characterization of a specific IgG monoclonal antibody toward the Lewis x antigen using splenocytes of Schistosoma mansoni-infected mice

(2013) Msano Mandalasi et al.   GLYCOBIOLOGY

Recognition of the Thomsen-Friedenreich Pancarcinoma Carbohydrate Antigen by a Lamprey Variable Lymphocyte Receptor

(2013) Ming Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunological Evaluation of a Synthetic Clostridium difficile Oligosaccharide Conjugate Vaccine Candidate and Identification of a Minimal Epitope

(2013) Christopher E. Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Therapeutic Targeting of Lewisy and Lewisb with a Novel Monoclonal Antibody 692/29

(2013) Philip Noble et al.   PLoS One

Computational Screening of the Human TF-Glycome Provides a Structural Definition for the Specificity of Anti-Tumor Antibody JAA-F11

(2013) Matthew B. Tessier et al.   PLoS One

Human H3N2 Influenza Viruses Isolated from 1968 To 2012 Show Varying Preference for Receptor Substructures with No Apparent Consequences for Disease or Spread

(2013) Shelly Gulati et al.   PLoS One

Sugar-Binding Proteins from Fish: Selection of High Affinity “Lambodies” That Recognize Biomedically Relevant Glycans

(2012) Xia Hong et al.   ACS Chemical Biology

Glycobiology of immune responses

(2012) Gabriel A. Rabinovich et al.   Annals of the New York Academy of Sciences

Carbohydrate microarrays

(2012) Sungjin Park et al.   CHEMICAL SOCIETY REVIEWS

Functional Glycomic Analysis of Human Milk Glycans Reveals the Presence of Virus Receptors and Embryonic Stem Cell Biomarkers

(2012) Ying Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-comparison of Protein Recognition of Sialic Acid Diversity on Two Novel Sialoglycan Microarrays

(2012) Vered Padler-Karavani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mannitou Monoclonal Antibody Uniquely Recognizes Paucimannose, a Marker for Human Cancer, Stemness, and Inflammation

(2012) Birgit Zipser et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

Glycan Microarrays for Decoding the Glycome

(2011) Cory D. Rillahan et al.   Annual Review of Biochemistry

Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface

(2010) Tyler B. M. Hickey et al.   CELLULAR MICROBIOLOGY

Determination of Carbohydrate-Binding Preferences of Human Galectins with Carbohydrate Microarrays

(2010) Tim Horlacher  et al.   CHEMBIOCHEM

Altered Receptor Specificity and Cell Tropism of D222G Hemagglutinin Mutants Isolated from Fatal Cases of Pandemic A(H1N1) 2009 Influenza Virus

(2010) Y. Liu et al.   JOURNAL OF VIROLOGY

Yeast-Elicited Cross-Reactive Antibodies to HIV Env Glycans Efficiently Neutralize Virions Expressing Exclusively High-Mannose N-Linked Glycans

(2010) C. Agrawal-Gamse et al.   JOURNAL OF VIROLOGY

Innate immune lectins kill bacteria expressing blood group antigen

(2010) Sean R Stowell et al.   NATURE MEDICINE

Multivalent ligand presentation as a central concept to study intricate carbohydrate–protein interactions

(2009) Narayanaswamy Jayaraman   CHEMICAL SOCIETY REVIEWS

Novel Fluorescent Glycan Microarray Strategy Reveals Ligands for Galectins

(2009) Xuezheng Song et al.   CHEMISTRY & BIOLOGY

Intravenous immunoglobulin contains a broad repertoire of anticarbohydrate antibodies that is not restricted to the IgG2 subclass

(2009) Stephan von Gunten et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Microarrays with Varying Carbohydrate Density Reveal Distinct Subpopulations of Serum Antibodies

(2009) Oyindasola Oyelaran et al.   JOURNAL OF PROTEOME RESEARCH

The repertoire of glycan determinants in the human glycome

(2009) Richard D. Cummings   Molecular BioSystems

Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray

(2009) Robert A Childs et al.   NATURE BIOTECHNOLOGY

Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens

(2008) Sean R. Stowell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibody responses of variable lymphocyte receptors in the lamprey

(2008) Matthew N Alder et al.   NATURE IMMUNOLOGY

Antigen Recognition by Variable Lymphocyte Receptors

(2008) B. W. Han et al.   SCIENCE

Tumor immunolocalization using 124I-iodine-labeled JAA-F11 antibody to Thomsen–Friedenreich alpha-linked antigen

(2007) Richa Chaturvedi et al.   APPLIED RADIATION AND ISOTOPES