Connexins in Astrocyte Migration

Connexin Hemichannels in Astrocytes: Role in CNS Disorders

(2019) LingYan Xing et al.   Frontiers in Molecular Neuroscience

In vitro inhibited effect of gap junction composed of Cx43 in the invasion and metastasis of testicular cancer resistanced to cisplatin

(2018) Dandan Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Astroglial Connexins as a Therapeutic Target for Alzheimer's Disease

(2018) Chenju Yi et al.   CURRENT PHARMACEUTICAL DESIGN

Protein–Protein Interactions with Connexin 43: Regulation and Function

(2018) Paul Sorgen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms of Endogenous Neuroprotective Effects of Astrocytes in Brain Injury

(2018) Michelle A. Bylicky et al.   Oxidative Medicine and Cellular Longevity

Intracellular calcium signal at the leading edge regulates mesodermal sheet migration during Xenopus gastrulation

(2018) Kentaro Hayashi et al.   Scientific Reports

Connexin-Mediated Functional and Metabolic Coupling Between Astrocytes and Neurons

(2018) Lady C. Mayorquin et al.   Frontiers in Molecular Neuroscience

Intracellular Ca2+ Increases and Connexin 43 Hemichannel Opening Are Necessary but Not Sufficient for Thy-1-Induced Astrocyte Migration

(2018) Raúl Lagos-Cabré et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effective Glucose Uptake by Human Astrocytes Requires Its Sequestration in the Endoplasmic Reticulum by Glucose-6-Phosphatase-β

(2018) Margit S. Müller et al.   CURRENT BIOLOGY

SRC3 expressed in BMSCs promotes growth and migration of multiple myeloma cells by regulating the expression of Cx43

(2017) Jie Jin et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Permeant-specific gating of connexin 30 hemichannels

(2017) Brian Skriver Nielsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

αVβ3 Integrin regulates astrocyte reactivity

(2017) Raúl Lagos-Cabré et al.   Journal of Neuroinflammation

Connexins and pannexins: At the junction of neuro-glial homeostasis & disease

(2017) Andrew S. Lapato et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Connexin membrane materials as potent inhibitors of breast cancer cell migration

(2017) Silvia Ferrati et al.   Journal of the Royal Society Interface

Phosphorylation regulates connexin43/ZO-1 binding and release, an important step in gap junction turnover

(2017) Anastasia F. Thévenin et al.   MOLECULAR BIOLOGY OF THE CELL

Single and collective cell migration: the mechanics of adhesions

(2017) Chiara De Pascalis et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after spinal cord injury

(2017) Masamitsu Hara et al.   NATURE MEDICINE

Mechanobiology of collective cell behaviours

(2017) Benoit Ladoux et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Connexin Hemichannels in Astrocytes: An Assessment of Controversies Regarding Their Functional Characteristics

(2017) Brian Skriver Nielsen et al.   NEUROCHEMICAL RESEARCH

Cell Biology of Astrocyte-Synapse Interactions

(2017) Nicola J. Allen et al.   NEURON

Astroglial correlates of neuropsychiatric disease: From astrocytopathy to astrogliosis

(2017) Ronald Kim et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Loss of Elp3 Impairs the Acetylation and Distribution of Connexin-43 in the Developing Cerebral Cortex

(2017) Sophie Laguesse et al.   Frontiers in Cellular Neuroscience

Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice

(2017) Eric Press et al.   Cell Death & Disease

Connexins in the Central Nervous System: Physiological Traits and Neuroprotective Targets

(2017) Nunzio Vicario et al.   Frontiers in Physiology

A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK

(2017) Myriam Jaraíz-Rodríguez et al.   Stem Cell Reports

Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration

(2016) Alvaro Alvarez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulation of gap junction channels and hemichannels by phosphorylation and redox changes: a revision

(2016) Kristin Pogoda et al.   BMC CELL BIOLOGY

Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis

(2016) Akshata A. Almad et al.   GLIA

Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration

(2016) Srikanth R. Polusani et al.   JOURNAL OF CELL SCIENCE

The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting

(2016) Christopher S. von Bartheld et al.   JOURNAL OF COMPARATIVE NEUROLOGY

FGF-1 Triggers Pannexin-1 Hemichannel Opening in Spinal Astrocytes of Rodents and Promotes Inflammatory Responses in Acute Spinal Cord Slices

(2016) J. M. Garre et al.   JOURNAL OF NEUROSCIENCE

Extracellular ATP induces graded reactive response of astrocytes and strengthens their antioxidative defense in vitro

(2016) Marija Adzic et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Early P2X7R-related astrogliosis in autoimmune encephalomyelitis

(2016) Tomasz Grygorowicz et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The front and rear of collective cell migration

(2016) Roberto Mayor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Astrocytes in Migration

(2016) Jiang Shan Zhan et al.   NEUROCHEMICAL RESEARCH

Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1

(2016) Cinzia Ambrosi et al.   PLoS One

“Targeting astrocytes in CNS injury and disease: A translational research approach”

(2016) Angela R. Filous et al.   PROGRESS IN NEUROBIOLOGY

An electrostatic mechanism for Ca2+-mediated regulation of gap junction channels

(2016) Brad C. Bennett et al.   Nature Communications

Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes

(2016) Ana González-Sánchez et al.   Oncotarget

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Connexin and pannexin signaling pathways, an architectural blueprint for CNS physiology and pathology?

(2015) Elke Decrock et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Connexins in migration during development and cancer

(2015) Maria Kotini et al.   DEVELOPMENTAL BIOLOGY

Activated microglia impairs neuroglial interaction by opening Cx43 hemichannels in hippocampal astrocytes

(2015) Verónica Abudara et al.   GLIA

Formation and maintenance of the BBB

(2015) Marie Blanchette et al.   MECHANISMS OF DEVELOPMENT

Phosphorylation of Connexin 43 by Cdk5 Modulates Neuronal Migration During Embryonic Brain Development

(2015) Guang-Jian Qi et al.   MOLECULAR NEUROBIOLOGY

Connexins in neurons and glia: targets for intervention in disease and injury

(2015) John O′Brien et al.   Neural Regeneration Research

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

Astrocytes Control Synapse Formation, Function, and Elimination

(2015) Won-Suk Chung et al.   Cold Spring Harbor Perspectives in Biology

Decreased connexin 43 in astrocytes inhibits the neuroinflammatory reaction in an acute mouse model of neonatal sepsis

(2015) Jing-Jing Zhou et al.   Neuroscience Bulletin

Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration

(2015) Ao Zhang et al.   Oncotarget

Astrocytic Cx 43 and Cx 40 in the mouse hippocampus during and after pilocarpine-induced status epilepticus

(2015) X. L. Wu et al.   EXPERIMENTAL BRAIN RESEARCH

The dual face of connexin-based astroglial Ca2+ communication: A key player in brain physiology and a prime target in pathology

(2014) Marijke De Bock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

(2014) Joell L. Solan et al.   FEBS LETTERS

Direct Regulation of Osteocytic Connexin 43 Hemichannels through AKT Kinase Activated by Mechanical Stimulation

(2014) Nidhi Batra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenotypic Heterogeneity and Plasticity of Isocortical and Hippocampal Astrocytes in the Human Brain

(2014) A. A. Sosunov et al.   JOURNAL OF NEUROSCIENCE

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

Spatial properties of astrocyte gap junction coupling in the rat hippocampus

(2014) S. Anders et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Astrocyte Reactivity and Reactive Astrogliosis: Costs and Benefits

(2014) Milos Pekny et al.   PHYSIOLOGICAL REVIEWS

Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress

(2014) Fabiola Rojas et al.   Frontiers in Cellular Neuroscience

Hemichannels in neurodegenerative diseases: is there a link to pathology?

(2014) Megan Bosch et al.   Frontiers in Cellular Neuroscience

Astrogliosis

(2014) Michael V. Sofroniew   Cold Spring Harbor Perspectives in Biology

Thy-1-mediated cell–cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4

(2013) Milene Kong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog

(2013) Swetlana Sirko et al.   Cell Stem Cell

All astrocytes are not created equal—the role of astroglia in brain injury

(2013) Darcie L Moore et al.   EMBO REPORTS

Traumatic scratch injury in astrocytes triggers calcium influx to activate the JNK/c-Jun/AP-1 pathway and switch on GFAP expression

(2013) Kai Gao et al.   GLIA

AQP5 is differentially regulated in astrocytes during metabolic and traumatic injuries

(2013) Rui Chao Chai et al.   GLIA

Astrocytes inhibit nitric oxide-dependent Ca2+dynamics in activated microglia: Involvement of ATP released via pannexin 1 channels

(2013) Juan A. Orellana et al.   GLIA

Importance of Connexin-43 based gap junction in cirrhosis and acute-on-chronic liver failure

(2013) Vairappan Balasubramaniyan et al.   JOURNAL OF HEPATOLOGY

Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation

(2013) Sophia Bardehle et al.   NATURE NEUROSCIENCE

Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury

(2013) Simon J. O’Carroll et al.   NEUROSCIENCE RESEARCH

Connexin 30 Expression and Frequency of Connexin Heterogeneity in Astrocyte Gap Junction Plaques Increase with Age in the Rat Retina

(2013) Hussein Mansour et al.   PLoS One

Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury

(2013) K. Kanemaru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system

(2013) Mieke Verslegers et al.   PROGRESS IN NEUROBIOLOGY

Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles

(2013) Christian Giaume et al.   Frontiers in Pharmacology

Gap junction proteins on the move: Connexins, the cytoskeleton and migration

(2012) Linda Matsuuchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Regulation of connexin expression by transcription factors and epigenetic mechanisms

(2012) Masahito Oyamada et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The biochemistry and function of pannexin channels

(2012) Silvia Penuela et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Extracellular K+ and Astrocyte Signaling via Connexin and Pannexin Channels

(2012) Eliana Scemes et al.   NEUROCHEMICAL RESEARCH

Channel-independent influence of connexin 43 on cell migration

(2011) Petra Kameritsch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Gap junctions in inherited human disorders of the central nervous system

(2011) Charles K. Abrams et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues

(2011) Lucrecia Márquez-Rosado et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Two non-vesicular ATP release pathways in the mouse erythrocyte membrane

(2011) Feng Qiu et al.   FEBS LETTERS

ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation

(2011) M. Henriquez et al.   JOURNAL OF CELL SCIENCE

Characterization of pannexin1 and pannexin3 and their regulation by androgens in the male reproductive tract of the adult rat

(2011) Patrick Turmel et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Multiscale approach to link red blood cell dynamics, shear viscosity, and ATP release

(2011) A. M. Forsyth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laminin-111 Stimulates Proliferation of Mouse Embryonic Stem Cells Through a Reduction of Gap Junctional Intercellular Communication via RhoA-Mediated Cx43 Phosphorylation and Dissociation of Cx43/ZO-1/Drebrin Complex

(2011) Han Na Suh et al.   STEM CELLS AND DEVELOPMENT

An angiotensin II- and NF-κB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension

(2010) Florian Alonso et al.   CARDIOVASCULAR RESEARCH

Astroglial networks: a step further in neuroglial and gliovascular interactions

(2010) Christian Giaume et al.   NATURE REVIEWS NEUROSCIENCE

Connexin 43 regulates astrocytic migration and proliferation in response to injury

(2010) B. Homkajorn et al.   NEUROSCIENCE LETTERS

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Pharmacological properties of a pore induced by raising intracellular Ca2+

(2009) R.X. Faria et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ca2+ regulation of connexin 43 hemichannels in C6 glioma and glial cells

(2009) Elke De Vuyst et al.   CELL CALCIUM

Receptors for myelin inhibitors: Structures and therapeutic opportunities

(2009) Zixuan Cao et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs

(2008) Zhongyong Li et al.   CLINICAL & EXPERIMENTAL METASTASIS

Interleukin-1β affects calcium signaling and in vitro cell migration of astrocyte progenitors

(2008) K STRIEDINGER et al.   JOURNAL OF NEUROIMMUNOLOGY

Endothelin-1 Regulates Astrocyte Proliferation and Reactive Gliosis via a JNK/c-Jun Signaling Pathway

(2008) A. Gadea et al.   JOURNAL OF NEUROSCIENCE

Connexin 43 Hemichannels Are Permeable to ATP

(2008) J. Kang et al.   JOURNAL OF NEUROSCIENCE

Identification of genes that regulate epithelial cell migration using an siRNA screening approach

(2008) Kaylene J. Simpson et al.   NATURE CELL BIOLOGY

What Is the Role of Astrocyte Calcium in Neurophysiology?

(2008) Cendra Agulhon et al.   NEURON

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE

Stretch-Induced Injury Alters Mitochondrial Membrane Potential and Cellular ATP in Cultured Astrocytes and Neurons

(2003) Syed M. Ahmed et al.   JOURNAL OF NEUROCHEMISTRY