αVβ3 Integrin regulates astrocyte reactivity

Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration

(2016) Alvaro Alvarez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis

(2016) Akshata A. Almad et al.   GLIA

Thy-1/β3 Integrin Interaction-Induced Apoptosis of Dermal Fibroblasts Is Mediated by Up-Regulation of FasL Expression

(2016) Manuela Schmidt et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interleukin-1β has trophic effects in microglia and its release is mediated by P2X7R pore

(2016) Mastura Monif et al.   Journal of Neuroinflammation

Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression

(2016) Savina Apolloni et al.   Journal of Neuroinflammation

Astrocytic GAP43 Induced by the TLR4/NF- B/STAT3 Axis Attenuates Astrogliosis-Mediated Microglial Activation and Neurotoxicity

(2016) C.-C. Hung et al.   JOURNAL OF NEUROSCIENCE

Early P2X7R-related astrogliosis in autoimmune encephalomyelitis

(2016) Tomasz Grygorowicz et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Pathophysiological and diagnostic implications of cortical dysfunction in ALS

(2016) Nimeshan Geevasinga et al.   Nature Reviews Neurology

Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease

(2016) Lana M. Osborn et al.   PROGRESS IN NEUROBIOLOGY

Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes

(2016) Alejandro Villarreal et al.   Frontiers in Cellular Neuroscience

Extracellular ATP enhances radiation-induced brain injury through microglial activation and paracrine signaling via P2X7 receptor

(2015) Pengfei Xu et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-8 upregulates integrin β3 expression and promotes estrogen receptor-negative breast cancer cell invasion by activating the PI3K/Akt/NF-κB pathway

(2015) Nan Shao et al.   CANCER LETTERS

Prenatal exposure to inflammatory conditions increases Cx43 and Panx1 unopposed channel opening and activation of astrocytes in the offspring effect on neuronal survival

(2015) Beatriz C. Avendaño et al.   GLIA

Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction

(2015) Vincent F. Fiore et al.   JOURNAL OF CELL BIOLOGY

Astrocytes Are Primed by Chronic Neurodegeneration to Produce Exaggerated Chemokine and Cell Infiltration Responses to Acute Stimulation with the Cytokines IL-1  and TNF- 

(2015) E. Hennessy et al.   JOURNAL OF NEUROSCIENCE

Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling

(2015) Fabiola Rojas et al.   Frontiers in Cellular Neuroscience

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrin–NF-κB–HIF-1α pathway

(2015) Lei Cao et al.   Oncotarget

Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice

(2014) Gang Chen et al.   BRAIN

Signaling Pathways Involved in Neuron-Astrocyte Adhesion and Migration

(2014) A. Cardenas et al.   CURRENT MOLECULAR MEDICINE

Orexin-A Promotes Cell Migration in Cultured Rat Astrocytes via Ca2+-Dependent PKCα and ERK1/2 Signals

(2014) Qing Shu et al.   PLoS One

Advances in treating amyotrophic lateral sclerosis: insights from pathophysiological studies

(2014) Steve Vucic et al.   TRENDS IN NEUROSCIENCES

Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress

(2014) Fabiola Rojas et al.   Frontiers in Cellular Neuroscience

Thy-1-mediated cell–cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4

(2013) Milene Kong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog

(2013) Swetlana Sirko et al.   Cell Stem Cell

All astrocytes are not created equal—the role of astroglia in brain injury

(2013) Darcie L Moore et al.   EMBO REPORTS

Ablation of P2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis

(2013) S. Apolloni et al.   HUMAN MOLECULAR GENETICS

Molecular mechanisms of syndecan-4 upregulation by TNF-  in the endothelium-like EAhy926 cells

(2013) E. Okuyama et al.   JOURNAL OF BIOCHEMISTRY

Importance of Connexin-43 based gap junction in cirrhosis and acute-on-chronic liver failure

(2013) Vairappan Balasubramaniyan et al.   JOURNAL OF HEPATOLOGY

Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability

(2013) Elsa Fritz et al.   JOURNAL OF NEUROPHYSIOLOGY

Type I Interferon and NF- B Activation Elicited by Herpes Simplex Virus gH/gL via  v 3 Integrin in Epithelial and Neuronal Cell Lines

(2013) T. Gianni et al.   JOURNAL OF VIROLOGY

Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation

(2013) Sophia Bardehle et al.   NATURE NEUROSCIENCE

Microglia are the major source of TNF-α and TGF-β1 in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin

(2013) Jennifer V. Welser-Alves et al.   NEUROCHEMISTRY INTERNATIONAL

Early pathogenesis in the adult-onset neurodegenerative disease amyotrophic lateral sclerosis

(2012) Brigitte van Zundert et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Transient acidification and subsequent proinflammatory cytokine stimulation of astrocytes induce distinct activation phenotypes

(2012) Nicole A. Renner et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation

(2011) M. Henriquez et al.   JOURNAL OF CELL SCIENCE

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

(2011) Amanda M Haidet-Phillips et al.   NATURE BIOTECHNOLOGY

An angiotensin II- and NF-κB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension

(2010) Florian Alonso et al.   CARDIOVASCULAR RESEARCH

Inhibition of cytokine-induced connexin43 hemichannel activity in astrocytes is neuroprotective

(2010) Nicolas Froger et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Astrocytes in the damaged brain: Molecular and cellular insights into their reactive response and healing potential

(2009) Annalisa Buffo et al.   BIOCHEMICAL PHARMACOLOGY

Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with  v 3 integrin that activates PKC  and RhoA

(2009) A. M. Avalos et al.   JOURNAL OF CELL SCIENCE

The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore

(2009) M. Monif et al.   JOURNAL OF NEUROSCIENCE

The bright side of the glial scar in CNS repair

(2009) Asya Rolls et al.   NATURE REVIEWS NEUROSCIENCE

Direct Thy-1/αVβ3 integrin interaction mediates neuron to astrocyte communication

(2008) Tamara Hermosilla et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH