Disclosing the Potential of the SARP-Type Regulator PapR2 for the Activation of Antibiotic Gene Clusters in Streptomycetes

The Balance Metabolism Safety Net: Integration of Stress Signals by Interacting Transcriptional Factors in Streptomyces and Related Actinobacteria

(2020) Juan F. Martín et al.   Frontiers in Microbiology

Activation of Secondary Metabolite Gene Clusters in Streptomyces clavuligerus by the PimM Regulator of Streptomyces natalensis

(2019) Yolanda Martínez-Burgo et al.   Frontiers in Microbiology

Identification of truncated form of NosP as a transcription factor to regulate the biosynthesis of nosiheptide

(2018) Xuri Wu et al.   FASEB JOURNAL

Patscanui: an intuitive web interface for searching patterns in DNA and protein data

(2018) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

New Insights into the Biosynthesis Pathway of Polyketide Alkaloid Argimycins P in Streptomyces argillaceus

(2018) Suhui Ye et al.   Frontiers in Microbiology

The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

(2018) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Production of a Novel Amide-Containing Polyene by Activating a Cryptic Biosynthetic Gene Cluster inStreptomycessp. MSC090213JE08

(2016) Danyao Du et al.   CHEMBIOCHEM

Gifted microbes for genome mining and natural product discovery

(2016) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Interspecies Complementation of the LuxR Family Pathway-Specific Regulator Involved in Macrolide Biosynthesis

(2016) SangJoon Mo et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

A Complex Signaling Cascade Governs Pristinamycin Biosynthesis in Streptomyces pristinaespiralis

(2015) Yvonne Mast et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Differential contributions of two SARP family regulatory genes to indigoidine biosynthesis in Streptomyces lavendulae FRI-5

(2014) Yohanes Novi Kurniawan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The gamma-butyrolactone receptors BulR1 and BulR2 of Streptomyces tsukubaensis: tacrolimus (FK506) and butyrolactone synthetases production control

(2014) Zahra Salehi-Najafabadi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A gene determining a new member of the SARP family contributes to transcription of genes for the synthesis of the angucycline polyketide auricin inStreptomyces aureofaciensCCM 3239

(2013) Alena Rehakova et al.   FEMS MICROBIOLOGY LETTERS

Triggers and cues that activate antibiotic production by actinomycetes

(2013) Hua Zhu et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Two-component systems in Streptomyces: key regulators of antibiotic complex pathways

(2013) Héctor Rodríguez et al.   Microbial Cell Factories

Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

(2013) G. Liu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Characterization of the Amicetin Biosynthesis Gene Cluster from Streptomyces vinaceusdrappus NRRL 2363 Implicates Two Alternative Strategies for Amide Bond Formation

(2012) Gaiyun Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

(2012) Kozo Ochi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identification of the Biosynthetic Gene Cluster and Regulatory Cascade for the Synergistic Antibacterial Antibiotics Griseoviridin and Viridogrisein inStreptomyces griseoviridis

(2012) Yunchang Xie et al.   CHEMBIOCHEM

Extracting regulator activity profiles by integration of de novo motifs and expression data: characterizing key regulators of nutrient depletion responses in Streptomyces coelicolor

(2012) Mudassar Iqbal et al.   NUCLEIC ACIDS RESEARCH

Metabolic and evolutionary insights into the closely-related species Streptomyces coelicolor and Streptomyces lividans deduced from high-resolution comparative genomic hybridization

(2011) Richard A Lewis et al.   BMC GENOMICS

The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239

(2011) R. Novakova et al.   MICROBIOLOGY-SGM

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis inStreptomycesSpecies

(2010) Hiroyasu Onaka et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Regulation of Lankamycin Biosynthesis inStreptomyces rocheiby Two SARP Genes,srrYandsrrZ

(2010) Toshihiro SUZUKI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Cross-talk of global nutritional regulators in the control of primary and secondary metabolism in Streptomyces

(2010) Juan F Martín et al.   Microbial Biotechnology

SanG, a transcriptional activator, controls nikkomycin biosynthesis through binding to the sanN-sanO intergenic region in Streptomyces ansochromogenes

(2009) X. He et al.   MICROBIOLOGY-SGM

Regulation of valanimycin biosynthesis in Streptomyces viridifaciens: characterization of VlmI as a Streptomyces antibiotic regulatory protein (SARP)

(2009) R. P. Garg et al.   MICROBIOLOGY-SGM

Hierarchical control of virginiamycin production in Streptomyces virginiae by three pathway-specific regulators: VmsS, VmsT and VmsR

(2009) N. Pulsawat et al.   MICROBIOLOGY-SGM

Elucidation of the Streptomyces coelicolor Pathway to 2-Undecylpyrrole, a Key Intermediate in Undecylprodiginine and Streptorubin B Biosynthesis

(2008) SangJoon Mo et al.   CHEMISTRY & BIOLOGY

Identification and Utility of FdmR1 as a Streptomyces Antibiotic Regulatory Protein Activator for Fredericamycin Production in Streptomyces griseus ATCC 49344 and Heterologous Hosts

(2008) Y. Chen et al.   JOURNAL OF BACTERIOLOGY

Identification of transcriptional activators for thienamycin and cephamycin C biosynthetic genes within the thienamycin gene cluster fromStreptomyces cattleya

(2008) Miriam Rodríguez et al.   MOLECULAR MICROBIOLOGY