Production of a Novel Amide-Containing Polyene by Activating a Cryptic Biosynthetic Gene Cluster inStreptomycessp. MSC090213JE08

New Simocyclinones: Surprising Evolutionary and Biosynthetic Insights

(2015) Oksana Bilyk et al.   ACS Chemical Biology

Identification and Characterization of the Streptazone E Biosynthetic Gene Cluster inStreptomycessp. MSC090213JE08

(2015) Shoto Ohno et al.   CHEMBIOCHEM

Clinical and Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit in the Decade following Implementation of an Active Detection and Isolation Program

(2015) Melissa U. Nelson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The re-emergence of natural products for drug discovery in the genomics era

(2015) Alan L. Harvey et al.   NATURE REVIEWS DRUG DISCOVERY

5-Alkyl-1,2,3,4-tetrahydroquinolines, New Membrane-Interacting Lipophilic Metabolites Produced by Combined Culture of Streptomyces nigrescens and Tsukamurella pulmonis

(2015) Ryosuke Sugiyama et al.   ORGANIC LETTERS

Chojalactones A–C, Cytotoxic Butanolides Isolated from Streptomyces sp. Cultivated with Mycolic Acid Containing Bacterium

(2015) Shotaro Hoshino et al.   ORGANIC LETTERS

In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly

(2015) Yi-Ling Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biosynthesis of Colabomycin E, a New Manumycin-Family Metabolite, Involves an Unusual Chain-Length Factor

(2014) Kateřina Petříčková et al.   CHEMBIOCHEM

Activation and identification of five clusters for secondary metabolites inStreptomyces albus J1074

(2014) Carlos Olano et al.   Microbial Biotechnology

Tricycloalternarenes F–H: Three new mixed terpenoids produced by an endolichenic fungus Ulocladium sp. using OSMAC method

(2013) Quan-Xin Wang et al.   FITOTERAPIA

Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

(2013) Haruo Ikeda et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements

(2013) Kozo Ochi et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Frenolicins C–G, Pyranonaphthoquinones from Streptomyces sp. RM-4-15

(2013) Xiachang Wang et al.   JOURNAL OF NATURAL PRODUCTS

Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

(2013) G. Liu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Single-cell sequencing-based technologies will revolutionize whole-organism science

(2013) Ehud Shapiro et al.   NATURE REVIEWS GENETICS

antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers

(2013) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

β-Glucuronidase as a Sensitive and Versatile Reporter in Actinomycetes

(2011) Maksym Myronovskyi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genetic manipulation of pathway regulation for overproduction of angucycline-like antibiotic auricin in Streptomyces aureofaciens CCM 3239

(2011) Renata Novakova et al.   FOLIA MICROBIOLOGICA

Sequencing technologies and genome sequencing

(2011) Chandra Shekhar Pareek et al.   JOURNAL OF APPLIED GENETICS

Strain improvement in actinomycetes in the postgenomic era

(2011) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Biosynthetic Gene Cluster of the Non-ribosomally Synthesized Cyclodepsipeptide Skyllamycin: Deciphering Unprecedented Ways of Unusual Hydroxylation Reactions

(2011) Stefan Pohle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

(2011) Marc Röttig et al.   NUCLEIC ACIDS RESEARCH

Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis inStreptomycesSpecies

(2010) Hiroyasu Onaka et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation

(2010) Yihua Chen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

(2010) Juan-Francisco Martín et al.   CURRENT OPINION IN MICROBIOLOGY

Manipulation of pathway regulation in Streptomyces globisporus for overproduction of the enediyne antitumor antibiotic C-1027

(2010) Yihua Chen et al.   JOURNAL OF ANTIBIOTICS

Biochemical and Genetic Insights into Asukamycin Biosynthesis

(2010) Zhe Rui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters

(2010) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters

(2010) Juan Pablo Gomez-Escribano et al.   Microbial Biotechnology

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS

Triggering cryptic natural product biosynthesis in microorganisms

(2009) Kirstin Scherlach et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

(2009) J. W.-H. Li et al.   SCIENCE

Identification and Utility of FdmR1 as a Streptomyces Antibiotic Regulatory Protein Activator for Fredericamycin Production in Streptomyces griseus ATCC 49344 and Heterologous Hosts

(2008) Y. Chen et al.   JOURNAL OF BACTERIOLOGY

pTONA5: A hyperexpression vector in streptomycetes

(2008) Tadashi Hatanaka et al.   PROTEIN EXPRESSION AND PURIFICATION