Two-component systems in Streptomyces: key regulators of antibiotic complex pathways

Integrated Metabolomics Approach Facilitates Discovery of an Unpredicted Natural Product Suite from Streptomyces coelicolor M145

(2013) Ashley M. Sidebottom et al.   ACS Chemical Biology

Expression, purification, crystallization and preliminary X-ray analysis of the extracellular sensory domain of DraK histidine kinase fromStreptomyces coelicolor

(2013) Kwon Joo Yeo et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

pH-dependent structural change of the extracellular sensor domain of the DraK histidine kinase from Streptomyces coelicolor

(2013) Kwon Joo Yeo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Towards a new science of secondary metabolism

(2013) Arryn Craney et al.   JOURNAL OF ANTIBIOTICS

Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

(2013) G. Liu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Thoughts and facts about antibiotics: Where we are now and where we are heading

(2012) János Bérdy   JOURNAL OF ANTIBIOTICS

Recent advances in engineering the central carbon metabolism of industrially important bacteria

(2012) Maria Papagianni   Microbial Cell Factories

Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor

(2012) Zhenyu Yu et al.   MOLECULAR MICROBIOLOGY

Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR inStreptomyces coelicolor

(2012) Rui Wang et al.   MOLECULAR MICROBIOLOGY

Diverse control of metabolism and other cellular processes in Streptomyces coelicolor by the PhoP transcription factor: genome-wide identification of in vivo targets

(2012) Nicholas E. E. Allenby et al.   NUCLEIC ACIDS RESEARCH

A Novel Two-Component System Involved in the Transition to Secondary Metabolism in Streptomyces coelicolor

(2012) Daniel Rozas et al.   PLoS One

The RNA Polymerase Omega Factor RpoZ Is Regulated by PhoP and Has an Important Role in Antibiotic Biosynthesis and Morphological Differentiation in Streptomyces coelicolor

(2011) Fernando Santos-Beneit et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

(2011) Gilles P. van Wezel et al.   NATURAL PRODUCT REPORTS

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

Novel Two-Component Systems Implied in Antibiotic Production in Streptomyces coelicolor

(2011) Ana Yepes et al.   PLoS One

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

(2011) L. Laureti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Sensor Kinases: Diversity in the Recognition of Environmental Signals

(2010) Tino Krell et al.   Annual Review of Microbiology

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

(2010) Juan-Francisco Martín et al.   CURRENT OPINION IN MICROBIOLOGY

Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1

(2010) Nancy L McKenzie et al.   JOURNAL OF ANTIBIOTICS

Carbon source regulation of antibiotic production

(2010) Sergio Sánchez et al.   JOURNAL OF ANTIBIOTICS

Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2)

(2010) M. Gottelt et al.   MICROBIOLOGY-SGM

Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms

(2010) Marnix H. Medema et al.   NATURE REVIEWS MICROBIOLOGY

P2CS: a database of prokaryotic two-component systems

(2010) Mohamed Barakat et al.   NUCLEIC ACIDS RESEARCH

Cross-talk of global nutritional regulators in the control of primary and secondary metabolism in Streptomyces

(2010) Juan F Martín et al.   Microbial Biotechnology

P2CS: a two-component system resource for prokaryotic signal transduction research

(2009) Mohamed Barakat et al.   BMC GENOMICS

Strategies for the Discovery of New Natural Products by Genome Mining

(2009) Malek Zerikly et al.   CHEMBIOCHEM

Cross-talk between an orphan response regulator and a noncognate histidine kinase inStreptomyces coelicolor

(2009) Weihua Wang et al.   FEMS MICROBIOLOGY LETTERS

Transmembrane topology of the AbsA1 sensor kinase of Streptomyces coelicolor

(2009) N. L. McKenzie et al.   MICROBIOLOGY-SGM

Cross-talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription

(2009) Fernando Santos-Beneit et al.   MOLECULAR MICROBIOLOGY

afsQ1-Q2-sigQ is a pleiotropic but conditionally required signal transduction system for both secondary metabolism and morphological development in Streptomyces coelicolor

(2008) Dan Shu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY