Structural basis of substrate recognition by a polypeptide processing and secretion transporter

Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease

(2019) Silvia C Bobeica et al.   eLife

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

(2019) Amer Alam et al.   SCIENCE

Structural basis of lipopolysaccharide extraction by the LptB2FGC complex

(2019) Yanyan Li et al.   NATURE

Conformation space of a heterodimeric ABC exporter under turnover conditions

(2019) Susanne Hofmann et al.   NATURE

Mechanics and pharmacology of substrate selection and transport by eukaryotic ABC exporters

(2019) Sriram Srikant et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1

(2018) Zachary Lee Johnson et al.   CELL

MetaUniDec: High-Throughput Deconvolution of Native Mass Spectra

(2018) Deseree J. Reid et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

(2018) Youngjin Kim et al.   SCIENCE

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

(2018) Ioannis Manolaridis et al.   NATURE

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis

(2018) Jasenko Zivanov et al.   IUCrJ

Structural basis of MsbA-mediated lipopolysaccharide transport

(2017) Wei Mi et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Addressing preferred specimen orientation in single-particle cryo-EM through tilting

(2017) Yong Zi Tan et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Mechanistic diversity in ATP-binding cassette (ABC) transporters

(2016) Kaspar P Locher   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanistic diversity in ATP-binding cassette (ABC) transporters

(2016) Kaspar P Locher   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles

(2015) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

The Role of the Detergent Micelle in Preserving the Structure of Membrane Proteins in the Gas Phase

(2015) Eamonn Reading et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alignment of cryo-EM movies of individual particles by optimization of image translations

(2015) John L. Rubinstein et al.   JOURNAL OF STRUCTURAL BIOLOGY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Crystal structures of a polypeptide processing and secretion transporter

(2015) David Yin-wei Lin et al.   NATURE

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions

(2015) Alan Brown et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of AMP-PNP–bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD–F

(2014) Vladimir M Korkhov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformation-independent structural comparison of macromolecules withProSMART

(2014) Robert A. Nicholls et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Boundary of the Nucleotide-Binding Domain of Streptococcus ComA Based on Functional and Structural Analysis

(2013) Seiji Ishii et al.   BIOCHEMISTRY

The Type 1 secretion pathway — The hemolysin system and beyond

(2013) Sabrina Thomas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure of AMP-PNP-bound vitamin B12 transporter BtuCD–F

(2012) Vladimir M. Korkhov et al.   NATURE

An RTX Transporter Tethers Its Unfolded Substrate during Secretion via a Unique N-Terminal Domain

(2012) Justin Lecher et al.   STRUCTURE

Lantibiotic Transporter Requires Cooperative Functioning of the Peptidase Domain and the ATP Binding Domain

(2011) Mami Nishie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structure of the Peptidase Domain ofStreptococcusComA, a Bifunctional ATP-binding Cassette Transporter Involved in the Quorum-sensing Pathway

(2010) Seiji Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

3V: cavity, channel and cleft volume calculator and extractor

(2010) N. R. Voss et al.   NUCLEIC ACIDS RESEARCH

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Fully automated, sequential tilt-series acquisition with Leginon

(2009) Christian Suloway et al.   JOURNAL OF STRUCTURAL BIOLOGY

Substrate Recognition Mechanism of the Peptidase Domain of the Quorum-Sensing-Signal−Producing ABC Transporter ComA fromStreptococcus†

(2008) Yatsugu Kotake et al.   BIOCHEMISTRY

Average protein density is a molecular-weight-dependent function

(2004) Hannes Fischer et al.   PROTEIN SCIENCE