Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways
Authors
Keywords
-
Journal
eLife
Volume 8, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2019-12-23
DOI
10.7554/elife.51163
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Protein-slaying drugs could be the next blockbuster therapies
- (2019) Megan Scudellari NATURE
- Targeted protein degradation: elements of PROTAC design
- (2019) Stacey-Lynn Paiva et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
- (2018) Michael P. Hughes et al. SCIENCE
- Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity
- (2018) Quinlan L. Sievers et al. BLOOD
- Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
- (2018) Jill J. Bouchard et al. MOLECULAR CELL
- UBE2G1 governs the destruction of cereblon neomorphic substrates
- (2018) Gang Lu et al. eLife
- The BioGRID interaction database: 2019 update
- (2018) Rose Oughtred et al. NUCLEIC ACIDS RESEARCH
- A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome
- (2017) Thierry Bertomeu et al. MOLECULAR AND CELLULAR BIOLOGY
- Two functionally distinct E2/E3 pairs coordinate sequential ubiquitination of a common substrate inCaenorhabditis elegansdevelopment
- (2017) Katja K. Dove et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
- (2016) Daniel C. Scott et al. CELL
- Induced protein degradation: an emerging drug discovery paradigm
- (2016) Ashton C. Lai et al. NATURE REVIEWS DRUG DISCOVERY
- Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM
- (2016) Alan S. L. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases
- (2015) Vinayak Vittal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrate degradation by the proteasome: A single-molecule kinetic analysis
- (2015) Y. Lu et al. SCIENCE
- SCF ubiquitin ligase-targeted therapies
- (2014) Jeffrey R. Skaar et al. NATURE REVIEWS DRUG DISCOVERY
- New insights into ubiquitin E3 ligase mechanism
- (2014) Christopher E Berndsen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Perilous journey: a tour of the ubiquitin–proteasome system
- (2014) Gary Kleiger et al. TRENDS IN CELL BIOLOGY
- RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination
- (2013) Meredith B. Metzger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins
- (2013) Nathan W. Pierce et al. CELL
- Building and remodelling Cullin-RING E3 ubiquitin ligases
- (2013) John R Lydeard et al. EMBO REPORTS
- Fbw7 dimerization determines the specificity and robustness of substrate degradation
- (2013) M. Welcker et al. GENES & DEVELOPMENT
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System
- (2013) Tim Wang et al. SCIENCE
- Deconjugation of Nedd8 from Cul1 Is Directly Regulated by Skp1-F-box and Substrate, and the COP9 Signalosome Inhibits Deneddylated SCF by a Noncatalytic Mechanism
- (2012) Ethan D. Emberley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Understanding Cullin-RING E3 Biology through Proteomics-based Substrate Identification
- (2012) J. Wade Harper et al. MOLECULAR & CELLULAR PROTEOMICS
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Structural Basis for a Reciprocal Regulation between SCF and CSN
- (2012) Radoslav I. Enchev et al. Cell Reports
- The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation
- (2011) Eric S. Fischer et al. CELL
- The Mechanism of Linkage-Specific Ubiquitin Chain Elongation by a Single-Subunit E2
- (2011) Katherine E. Wickliffe et al. CELL
- Skyline: an open source document editor for creating and analyzing targeted proteomics experiments
- (2010) Brendan MacLean et al. BIOINFORMATICS
- Structural assembly of cullin-RING ubiquitin ligase complexes
- (2010) Erik S Zimmerman et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Priming and Extending: A UbcH5/Cdc34 E2 Handoff Mechanism for Polyubiquitination on a SCF Substrate
- (2010) Kenneth Wu et al. MOLECULAR CELL
- RING Domain E3 Ubiquitin Ligases
- (2009) Raymond J. Deshaies et al. Annual Review of Biochemistry
- Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates
- (2009) Gary Kleiger et al. CELL
- The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCFCdc4
- (2009) Gary Kleiger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detection of sequential polyubiquitylation on a millisecond timescale
- (2009) Nathan W. Pierce et al. NATURE
- Multimodal Activation of the Ubiquitin Ligase SCF by Nedd8 Conjugation
- (2008) Anjanabha Saha et al. MOLECULAR CELL
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started