Deconjugation of Nedd8 from Cul1 Is Directly Regulated by Skp1-F-box and Substrate, and the COP9 Signalosome Inhibits Deneddylated SCF by a Noncatalytic Mechanism
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Deconjugation of Nedd8 from Cul1 Is Directly Regulated by Skp1-F-box and Substrate, and the COP9 Signalosome Inhibits Deneddylated SCF by a Noncatalytic Mechanism
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 35, Pages 29679-29689
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-07-06
DOI
10.1074/jbc.m112.352484
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation
- (2012) Susanne Bandau et al. BMC BIOLOGY
- NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway
- (2012) Willem den Besten et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Neurospora COP9 Signalosome Integrity Plays Major Roles for Hyphal Growth, Conidial Development, and Circadian Function
- (2012) Zhipeng Zhou et al. PLoS Genetics
- The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation
- (2011) Eric S. Fischer et al. CELL
- Characterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activity
- (2011) Yin Yin Choo et al. MOLECULAR BIOLOGY OF THE CELL
- Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response
- (2011) Y-H Lee et al. ONCOGENE
- Dynamics of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative Proteomics
- (2010) Eric J. Bennett et al. CELL
- The Steady-State Repertoire of Human SCF Ubiquitin Ligase Complexes Does Not Require Ongoing Nedd8 Conjugation
- (2010) J. Eugene Lee et al. MOLECULAR & CELLULAR PROTEOMICS
- Recruitment of the inhibitor Cand1 to the cullin substrate adaptor site mediates interaction to the neddylation site
- (2010) Kerstin Helmstaedt et al. MOLECULAR BIOLOGY OF THE CELL
- An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase
- (2010) Stephen Orlicky et al. NATURE BIOTECHNOLOGY
- Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase
- (2010) Mariam Aghajan et al. NATURE BIOTECHNOLOGY
- The ubiquitous nature of cancer: the role of the SCFFbw7 complex in development and transformation
- (2010) K M Crusio et al. ONCOGENE
- JAB1/CSN5: a new player in cell cycle control and cancer
- (2010) Terry J Shackleford et al. Cell Division
- RING Domain E3 Ubiquitin Ligases
- (2009) Raymond J. Deshaies et al. Annual Review of Biochemistry
- Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates
- (2009) Gary Kleiger et al. CELL
- A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene
- (2009) Ji Luo et al. CELL
- The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCFCdc4
- (2009) Gary Kleiger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detection of sequential polyubiquitylation on a millisecond timescale
- (2009) Nathan W. Pierce et al. NATURE
- An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
- (2009) Teresa A. Soucy et al. NATURE
- Symmetrical Modularity of the COP9 Signalosome Complex Suggests its Multifunctionality
- (2009) Michal Sharon et al. STRUCTURE
- CSN5 Isopeptidase Activity Links COP9 Signalosome Activation to Breast Cancer Progression
- (2008) A. S. Adler et al. CANCER RESEARCH
- Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation
- (2008) David M. Duda et al. CELL
- Multimodal Activation of the Ubiquitin Ligase SCF by Nedd8 Conjugation
- (2008) Anjanabha Saha et al. MOLECULAR CELL
- The COP9 signalosome: more than a protease
- (2008) N WEI et al. TRENDS IN BIOCHEMICAL SCIENCES
- Cullin-RING ubiquitin ligases: global regulation and activation cycles
- (2008) Dimple R Bosu et al. Cell Division
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started