Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways
出版年份 2019 全文链接
标题
Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways
作者
关键词
-
出版物
eLife
Volume 8, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2019-12-23
DOI
10.7554/elife.51163
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Protein-slaying drugs could be the next blockbuster therapies
- (2019) Megan Scudellari NATURE
- Targeted protein degradation: elements of PROTAC design
- (2019) Stacey-Lynn Paiva et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
- (2018) Michael P. Hughes et al. SCIENCE
- Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity
- (2018) Quinlan L. Sievers et al. BLOOD
- Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
- (2018) Jill J. Bouchard et al. MOLECULAR CELL
- UBE2G1 governs the destruction of cereblon neomorphic substrates
- (2018) Gang Lu et al. eLife
- The BioGRID interaction database: 2019 update
- (2018) Rose Oughtred et al. NUCLEIC ACIDS RESEARCH
- A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome
- (2017) Thierry Bertomeu et al. MOLECULAR AND CELLULAR BIOLOGY
- Two functionally distinct E2/E3 pairs coordinate sequential ubiquitination of a common substrate inCaenorhabditis elegansdevelopment
- (2017) Katja K. Dove et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
- (2016) Daniel C. Scott et al. CELL
- Induced protein degradation: an emerging drug discovery paradigm
- (2016) Ashton C. Lai et al. NATURE REVIEWS DRUG DISCOVERY
- Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM
- (2016) Alan S. L. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases
- (2015) Vinayak Vittal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrate degradation by the proteasome: A single-molecule kinetic analysis
- (2015) Y. Lu et al. SCIENCE
- SCF ubiquitin ligase-targeted therapies
- (2014) Jeffrey R. Skaar et al. NATURE REVIEWS DRUG DISCOVERY
- New insights into ubiquitin E3 ligase mechanism
- (2014) Christopher E Berndsen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Perilous journey: a tour of the ubiquitin–proteasome system
- (2014) Gary Kleiger et al. TRENDS IN CELL BIOLOGY
- RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination
- (2013) Meredith B. Metzger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins
- (2013) Nathan W. Pierce et al. CELL
- Building and remodelling Cullin-RING E3 ubiquitin ligases
- (2013) John R Lydeard et al. EMBO REPORTS
- Fbw7 dimerization determines the specificity and robustness of substrate degradation
- (2013) M. Welcker et al. GENES & DEVELOPMENT
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System
- (2013) Tim Wang et al. SCIENCE
- Deconjugation of Nedd8 from Cul1 Is Directly Regulated by Skp1-F-box and Substrate, and the COP9 Signalosome Inhibits Deneddylated SCF by a Noncatalytic Mechanism
- (2012) Ethan D. Emberley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Understanding Cullin-RING E3 Biology through Proteomics-based Substrate Identification
- (2012) J. Wade Harper et al. MOLECULAR & CELLULAR PROTEOMICS
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Structural Basis for a Reciprocal Regulation between SCF and CSN
- (2012) Radoslav I. Enchev et al. Cell Reports
- The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation
- (2011) Eric S. Fischer et al. CELL
- The Mechanism of Linkage-Specific Ubiquitin Chain Elongation by a Single-Subunit E2
- (2011) Katherine E. Wickliffe et al. CELL
- Skyline: an open source document editor for creating and analyzing targeted proteomics experiments
- (2010) Brendan MacLean et al. BIOINFORMATICS
- Structural assembly of cullin-RING ubiquitin ligase complexes
- (2010) Erik S Zimmerman et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Priming and Extending: A UbcH5/Cdc34 E2 Handoff Mechanism for Polyubiquitination on a SCF Substrate
- (2010) Kenneth Wu et al. MOLECULAR CELL
- RING Domain E3 Ubiquitin Ligases
- (2009) Raymond J. Deshaies et al. Annual Review of Biochemistry
- Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates
- (2009) Gary Kleiger et al. CELL
- The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCFCdc4
- (2009) Gary Kleiger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Detection of sequential polyubiquitylation on a millisecond timescale
- (2009) Nathan W. Pierce et al. NATURE
- Multimodal Activation of the Ubiquitin Ligase SCF by Nedd8 Conjugation
- (2008) Anjanabha Saha et al. MOLECULAR CELL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More