DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer

EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration

(2018) Nicole M. Aiello et al.   DEVELOPMENTAL CELL

TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence

(2018) Isabel Puig et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion

(2018) Alexandra C. Title et al.   Nature Communications

Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity

(2017) Nicolas Skrypek et al.   TRENDS IN GENETICS

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

(2016) Bernard Thienpont et al.   NATURE

A genetic cell context-dependent role for ZEB1 in lung cancer

(2016) Ting Zhang et al.   Nature Communications

Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition

(2016) Valentine Comaills et al.   Cell Reports

Unraveling epigenetic regulation of epithelial mesenchymal transition

(2016) Rattiyaporn Kanlaya et al.   Translational Cancer Research

Role of EMT in Metastasis and Therapy Resistance

(2016) Bethany Smith et al.   Journal of Clinical Medicine

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

NF-kB signaling mediates acquired resistance after PARP inhibition

(2015) Yuko Nakagawa et al.   Oncotarget

The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy

(2015) Brock Humphries et al.   Oncotarget

Slug-Dependent Upregulation of L1CAM Is Responsible for the Increased Invasion Potential of Pancreatic Cancer Cells following Long-Term 5-FU Treatment

(2015) Kaja Lund et al.   PLoS One

TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer

(2015) José A. Galván et al.   Oncotarget

Comparison and quantitative verification of mapping algorithms for whole-genome bisulfite sequencing

(2014) Govindarajan Kunde-Ramamoorthy et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling

(2013) Su Jung Song et al.   CELL

Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance

(2013) P. Jia et al.   GENOME RESEARCH

Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state

(2013) Y.-Y. Lim et al.   JOURNAL OF CELL SCIENCE

The causes and consequences of genetic heterogeneity in cancer evolution

(2013) Rebecca A. Burrell et al.   NATURE

The epigenetics of epithelial-mesenchymal plasticity in cancer

(2013) Wai Leong Tam et al.   NATURE MEDICINE

Liquid biopsy: monitoring cancer-genetics in the blood

(2013) Emily Crowley et al.   Nature Reviews Clinical Oncology

The miR-200 and miR-221/222 microRNA Families: Opposing Effects on Epithelial Identity

(2012) Erin N. Howe et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine

(2012) Miao Yu et al.   Nature Protocols

Characterization of a cell culture model for clinically aggressive hepatocellular carcinoma induced by chronic hypoxia

(2011) Hannah van Malenstein et al.   CANCER LETTERS

The emerging role of miR-200 family of MicroRNAs in epithelial-mesenchymal transition and cancer metastasis

(2011) Manav Korpal et al.   RNA Biology

Pancreatic Cancers Epigenetically Silence SIP1 and Hypomethylate and Overexpress miR-200a/200b in Association with Elevated Circulating miR-200a and miR-200b Levels

(2010) A. Li et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL