RHS-elements function as type II toxin-antitoxin modules that regulate intra-macrophage replication of Salmonella Typhimurium

Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology

(2018) Alexander Harms et al.   MOLECULAR CELL

PAAR-Rhs proteins harbor various C-terminal toxins to diversify the antibacterial pathways of type VI secretion systems

(2017) Jiale Ma et al.   ENVIRONMENTAL MICROBIOLOGY

Toxin-antitoxin systems in bacterial growth arrest and persistence

(2016) Rebecca Page et al.   Nature Chemical Biology

SalmonellaTyphimurium utilizes a T6SS-mediated antibacterial weapon to establish in the host gut

(2016) Thibault G. Sana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways

(2016) Meenakumari Muthuramalingam et al.   Toxins

H-NS Silencing of the Salmonella Pathogenicity Island 6-Encoded Type VI Secretion System Limits Salmonella enterica Serovar Typhimurium Interbacterial Killing

(2015) Yannick R. Brunet et al.   INFECTION AND IMMUNITY

Intraspecies Competition in Serratia marcescens Is Mediated by Type VI-Secreted Rhs Effectors and a Conserved Effector-Associated Accessory Protein

(2015) Juliana Alcoforado Diniz et al.   JOURNAL OF BACTERIOLOGY

Genetically distinct pathways guide effector export through the type VI secretion system

(2014) John C. Whitney et al.   MOLECULAR MICROBIOLOGY

Type VI secretion system effectors: poisons with a purpose

(2014) Alistair B. Russell et al.   NATURE REVIEWS MICROBIOLOGY

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium

(2014) Sanna Koskiniemi et al.   PLoS Genetics

An Infection-Relevant Transcriptomic Compendium for Salmonella enterica Serovar Typhimurium

(2013) Carsten Kröger et al.   Cell Host & Microbe

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device

(2013) Jason N. Busby et al.   NATURE

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike

(2013) Mikhail M. Shneider et al.   NATURE

Rhs proteins from diverse bacteria mediate intercellular competition

(2013) S. Koskiniemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A regulatory role for Staphylococcus aureus toxin–antitoxin system PemIKSa

(2013) Michal Bukowski et al.   Nature Communications

Comprehensive Assignment of Roles for Salmonella Typhimurium Genes in Intestinal Colonization of Food-Producing Animals

(2013) Roy R. Chaudhuri et al.   PLoS Genetics

A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice

(2013) Miguel A. De la Cruz et al.   PLoS Pathogens

Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics

(2012) Dapeng Zhang et al.   Biology Direct

Type VI Secretion System-Associated Gene Clusters Contribute to Pathogenesis of Salmonella enterica Serovar Typhimurium

(2012) David T. Mulder et al.   INFECTION AND IMMUNITY

An rhs gene of Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome

(2012) V. L. Kung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems

(2012) R. P. Morse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxin-Antitoxin Systems Are Important for Niche-Specific Colonization and Stress Resistance of Uropathogenic Escherichia coli

(2012) J. Paul Norton et al.   PLoS Pathogens

Phylogenetic Analysis of the Teneurins: Conserved Features and Premetazoan Ancestry

(2011) R. P. Tucker et al.   MOLECULAR BIOLOGY AND EVOLUTION

Selfish genetic elements, genetic conflict, and evolutionary innovation

(2011) J. H. Werren   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Functional Toxin/Immunity Genes Linked to Contact-Dependent Growth Inhibition (CDI) and Rearrangement Hotspot (Rhs) Systems

(2011) Stephen J. Poole et al.   PLoS Genetics

A Type VI Secretion System of Pseudomonas aeruginosa Targets a Toxin to Bacteria

(2010) Rachel D. Hood et al.   Cell Host & Microbe

A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria

(2010) Stephanie K. Aoki et al.   NATURE

In vivo actin cross-linking induced by Vibrio cholerae type VI secretion system is associated with intestinal inflammation

(2010) A. T. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of intracellular bacterial replication at the single cell level

(2010) Sophie Helaine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary diversification of an ancient gene family (rhs) through C-terminal displacement

(2009) Andrew P Jackson et al.   BMC GENOMICS

Three Mycobacterium tuberculosis Rel Toxin-Antitoxin Modules Inhibit Mycobacterial Growth and Are Expressed in Infected Human Macrophages

(2008) S. B. Korch et al.   JOURNAL OF BACTERIOLOGY

Salmonellae interplay with host cells

(2007) Andrea Haraga et al.   NATURE REVIEWS MICROBIOLOGY