Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast

Cell Cycle-Regulated Transcription of CENP-A by the MBF Complex Ensures Optimal Level of CENP-A for Centromere Formation

(2019) David Aristizabal-Corrales et al.   GENETICS

The E3-ligases SCFPpa and APC/CCdh1 co-operate to regulate CENP-ACID expression across the cell cycle

(2019) Olga Moreno-Moreno et al.   NUCLEIC ACIDS RESEARCH

A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A

(2018) Sultan Ciftci-Yilmaz et al.   GENETICS

N-terminal Sumoylation of Centromeric Histone H3 Variant Cse4 Regulates Its Proteolysis To Prevent Mislocalization to Non-centromeric Chromatin

(2018) Kentaro Ohkuni et al.   G3-Genes Genomes Genetics

A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A

(2018) Sultan Ciftci-Yilmaz et al.   GENETICS

Essential role for centromeric factors following p53 loss and oncogenic transformation

(2017) Dan Filipescu et al.   GENES & DEVELOPMENT

Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells

(2017) Roshan L. Shrestha et al.   Oncotarget

Multiple E3s promote the degradation of histone H3 variant Cse4

(2017) Haili Cheng et al.   Scientific Reports

Elevated expression of the centromere protein-A(CENP-A)-encoding gene as a prognostic and predictive biomarker in human cancers

(2016) Xia Sun et al.   INTERNATIONAL JOURNAL OF CANCER

The F-box Protein Rcy1 Is Involved in the Degradation of Histone H3 Variant Cse4 and Genome Maintenance

(2016) Haili Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polo kinase Cdc5 associates with centromeres to facilitate the removal of centromeric cohesin during mitosis

(2016) Prashant K. Mishra et al.   MOLECULAR BIOLOGY OF THE CELL

A global genetic interaction network maps a wiring diagram of cellular function

(2016) M. Costanzo et al.   SCIENCE

Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy

(2016) Weiguo Zhang et al.   Nature Communications

Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects

(2016) Erica M. Hildebrand et al.   PLoS Genetics

Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination

(2015) Prashant K. Mishra et al.   MOLECULAR BIOLOGY OF THE CELL

The molecular basis for centromere identity and function

(2015) Kara L. McKinley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells

(2015) Rajbir K Athwal et al.   Epigenetics & Chromatin

The FACT complex interacts with the E3 ubiquitin ligase Psh1 to prevent ectopic localization of CENP-A

(2014) Gary M.R. Deyter et al.   GENES & DEVELOPMENT

Ectopic Centromere Nucleation by CENP-A in Fission Yeast

(2014) Marlyn Gonzalez et al.   GENETICS

Regulation of the Histone Deacetylase Hst3 by Cyclin-dependent Kinases and the Ubiquitin Ligase SCFCdc4

(2014) Neda Delgoshaie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation by Casein Kinase 2 Facilitates Psh1 Protein-assisted Degradation of Cse4 Protein

(2014) Geetha S. Hewawasam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A

(2014) Peter Hornung et al.   JOURNAL OF CELL BIOLOGY

Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX

(2014) Nicolas Lacoste et al.   MOLECULAR CELL

The 19S proteasome subunit Rpt3 regulates distribution of CENP-A by associating with centromeric chromatin

(2014) Teppei Kitagawa et al.   Nature Communications

Structural Integrity of Centromeric Chromatin and Faithful Chromosome Segregation Requires Pat1

(2013) P. K. Mishra et al.   GENETICS

A Novel Role of the N Terminus of Budding Yeast Histone H3 Variant Cse4 in Ubiquitin-Mediated Proteolysis

(2013) W. C. Au et al.   GENETICS

Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae

(2013) Lars Boeckmann et al.   MOLECULAR BIOLOGY OF THE CELL

Sequential primed kinases create a damage-responsive phosphodegron on Eco1

(2013) Nicholas A Lyons et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Telomeric Repeats Facilitate CENP-ACnp1 Incorporation via Telomere Binding Proteins

(2013) Araceli G. Castillo et al.   PLoS One

An expanded tool kit for the auxin-inducible degron system in budding yeast

(2013) Magdalena Morawska et al.   YEAST

The Ubiquitin-Proteasome System of Saccharomyces cerevisiae

(2012) D. Finley et al.   GENETICS

Expression and prognostic significance of centromere protein A in human lung adenocarcinoma

(2012) Qing Wu et al.   LUNG CANCER

Fbw7 and p53 Cooperatively Suppress Advanced and Chromosomally Unstable Intestinal Cancer

(2012) J. E. Grim et al.   MOLECULAR AND CELLULAR BIOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Methylation of CenH3 arginine 37 regulates kinetochore integrity and chromosome segregation

(2012) A. Samel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Factors That Promote H3 Chromatin Integrity during Transcription Prevent Promiscuous Deposition of CENP-ACnp1 in Fission Yeast

(2012) Eun Shik Choi et al.   PLoS Genetics

The mitotic Clb cyclins are required to alleviate HIR-mediated repression of the yeast histone genes at the G1/S transition

(2011) Amit Dipak Amin et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The F Box Protein Partner of Paired Regulates Stability of Drosophila Centromeric Histone H3, CenH3CID

(2011) Olga Moreno-Moreno et al.   CURRENT BIOLOGY

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

(2011) Zhijian Li et al.   NATURE BIOTECHNOLOGY

ShRNA-Targeted Centromere Protein A Inhibits Hepatocellular Carcinoma Growth

(2011) Yongmei Li et al.   PLoS One

A Role for Snf2-Related Nucleosome-Spacing Enzymes in Genome-Wide Nucleosome Organization

(2011) T. Gkikopoulos et al.   SCIENCE

Misregulation of Scm3p/HJURP Causes Chromosome Instability in Saccharomyces cerevisiae and Human Cells

(2011) Prashant K. Mishra et al.   PLoS Genetics

Overlapping Regulation of CenH3 Localization and Histone H3 Turnover by CAF-1 and HIR Proteins in Saccharomyces cerevisiae

(2010) J. L. d. Rosa et al.   GENETICS

A Transcriptional Activator Is Part of an SCF Ubiquitin Ligase to Control Degradation of Its Cofactors

(2010) Ikram Ouni et al.   MOLECULAR CELL

Psh1 Is an E3 Ubiquitin Ligase that Targets the Centromeric Histone Variant Cse4

(2010) Geetha Hewawasam et al.   MOLECULAR CELL

An E3 Ubiquitin Ligase Prevents Ectopic Localization of the Centromeric Histone H3 Variant via the Centromere Targeting Domain

(2010) Prerana Ranjitkar et al.   MOLECULAR CELL

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Efficient yeast ChIP-Seq using multiplex short-read DNA sequencing

(2009) Philippe Lefrançois et al.   BMC GENOMICS

Lessons from Fungal F-Box Proteins

(2009) Wilfried Jonkers et al.   EUKARYOTIC CELL

CENPA overexpression promotes genome instability in pRb-depleted human cells

(2009) Angela Amato et al.   Molecular Cancer

Cse4 Is Part of an Octameric Nucleosome in Budding Yeast

(2009) Raymond Camahort et al.   MOLECULAR CELL

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Altered Dosage and Mislocalization of Histone H3 and Cse4p Lead to Chromosome Loss in Saccharomyces cerevisiae

(2008) W.-C. Au et al.   GENETICS