Pancreatic β cell microRNA-26a alleviates type 2 diabetes by improving peripheral insulin sensitivity and preserving β cell function

The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation

(2019) Haixia Xu et al.   Molecular Metabolism

Phospholipase C-β1 potentiates glucose-stimulated insulin secretion

(2019) Hyeon-Jeong Hwang et al.   FASEB JOURNAL

miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19

(2019) Asha Acharya et al.   GENES & DEVELOPMENT

Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion

(2018) Takuro Matsuzawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The interplay between noncoding RNAs and insulin in diabetes

(2018) Yan Tian et al.   CANCER LETTERS

MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma

(2018) Xiang Zhang et al.   CANCER LETTERS

An Integrated View of Immunometabolism

(2018) Yun Sok Lee et al.   CELL

Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases

(2018) Varman T. Samuel et al.   Cell Metabolism

Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes

(2018) Cristina Aguayo-Mazzucato et al.   Cell Metabolism

Diet-induced β-cell insulin resistance results in reversible loss of functional β-cell mass

(2018) Meike Paschen et al.   FASEB JOURNAL

Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress

(2018) Zhenqi Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles in obesity and diabetes mellitus

(2018) Fabián Pardo et al.   MOLECULAR ASPECTS OF MEDICINE

Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells

(2018) Wei Yan et al.   NATURE CELL BIOLOGY

Extracellular vesicles in cancer — implications for future improvements in cancer care

(2018) Rong Xu et al.   Nature Reviews Clinical Oncology

New ADCY3 Variants Dance in Obesity Etiology

(2018) Yan Tian et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mild Suppression of Hyperinsulinemia to Treat Obesity and Insulin Resistance

(2018) Melissa M. Page et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Accumulation of succinate controls activation of adipose tissue thermogenesis

(2018) Evanna L. Mills et al.   NATURE

Targeting noncoding RNAs in disease

(2017) Brian D. Adams et al.   JOURNAL OF CLINICAL INVESTIGATION

PI(3,4,5)P 3 Engagement Restricts Akt Activity to Cellular Membranes

(2017) Michael Ebner et al.   MOLECULAR CELL

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

(2017) Yalin Zhang et al.   NATURE

Insulin action and resistance in obesity and type 2 diabetes

(2017) Michael P Czech   NATURE MEDICINE

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Down-regulation of miR-26a-5p in hepatocellular carcinoma: A qRT-PCR and bioinformatics study

(2017) Liang Liang et al.   PATHOLOGY RESEARCH AND PRACTICE

Vascular-derived connective tissue growth factor (Ctgf) is critical for pregnancy-induced β cell hyperplasia in adult mice

(2017) Raymond C. Pasek et al.   Islets

Dnmt3a is an epigenetic mediator of adipose insulin resistance

(2017) Dongjoo You et al.   eLife

Hyperinsulinaemic hypoglycaemia in children and adults

(2017) Pratik Shah et al.   Lancet Diabetes & Endocrinology

Secretagogin affects insulin secretion in pancreatic  -cells by regulating actin dynamics and focal adhesion

(2016) S.-Y. Yang et al.   BIOCHEMICAL JOURNAL

MicroRNAs in CD4 + T cell subsets are markers of disease risk and T cell dysfunction in individuals at risk for type 1 diabetes

(2016) Yuxia Zhang et al.   JOURNAL OF AUTOIMMUNITY

The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux

(2016) Varman T. Samuel et al.   JOURNAL OF CLINICAL INVESTIGATION

A thrifty variant in CREBRF strongly influences body mass index in Samoans

(2016) Ryan L Minster et al.   NATURE GENETICS

The potential of endurance exercise-derived exosomes to treat metabolic diseases

(2016) Adeel Safdar et al.   Nature Reviews Endocrinology

The skeleton in the closet: actin cytoskeletal remodeling in β-cell function

(2015) Caroline Arous et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pancreatic β-cell identity, glucose sensing and the control of insulin secretion

(2015) Guy A. Rutter et al.   BIOCHEMICAL JOURNAL

The Ia-2β intronic miRNA, miR-153, is a negative regulator of insulin and dopamine secretion through its effect on the Cacna1c gene in mice

(2015) Huanyu Xu et al.   DIABETOLOGIA

MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids

(2015) Xianghui Fu et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-26a enhances autophagy to protect against ethanol-induced acute liver injury

(2015) Weidong Han et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

miR-101a and miR-30b contribute to inflammatory cytokine-mediated β-cell dysfunction

(2015) Ying Zheng et al.   LABORATORY INVESTIGATION

Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction

(2015) Ende Zhao et al.   NATURE IMMUNOLOGY

PI3K-C2α Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation

(2015) Barbara Leibiger et al.   Cell Reports

Identification of miR-26a as a Target Gene of Bile Acid Receptor GPBAR-1/TGR5

(2015) Xiaosong Chen et al.   PLoS One

MicroRNA-26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin

(2015) Xiang Zhang et al.   Oncotarget

Connective Tissue Growth Factor Modulates Adult β-Cell Maturity and Proliferation to Promote β-Cell Regeneration in Mice

(2014) Kimberly G. Riley et al.   DIABETES

Role of the SIK2–p35–PJA2 complex in pancreatic β-cell functional compensation

(2014) Jun-Ichi Sakamaki et al.   NATURE CELL BIOLOGY

miR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis

(2013) X Fu et al.   ONCOGENE

MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation

(2013) X. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-26 Family Is Required for Human Adipogenesis and Drives Characteristics of Brown Adipocytes

(2013) Michael Karbiener et al.   STEM CELLS

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Production

(2012) Arya E. Mehran et al.   Cell Metabolism

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2

(2011) J. Lu et al.   CANCER RESEARCH

miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors

(2011) Tal Melkman-Zehavi et al.   EMBO JOURNAL

miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice

(2010) Zhipeng Meng et al.   HEPATOLOGY

Mechanical Stretch Up-regulates MicroRNA-26a and Induces Human Airway Smooth Muscle Hypertrophy by Suppressing Glycogen Synthase Kinase-3β

(2010) Junaith S. Mohamed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols

Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes

(2009) W.-X. Wang et al.   RNA

Insulin Signaling in the Pancreatic β-Cell

(2008) Ingo B. Leibiger et al.   Annual Review of Nutrition