HHV-6A infection induces amyloid-beta expression and activation of microglial cells

KIR2DS2/KIR2DL2/HLA-C1 Haplotype Is Associated with Alzheimer’s Disease: Implication for the Role of Herpesvirus Infections

(2019) Roberta Rizzo et al.   JOURNAL OF ALZHEIMERS DISEASE

The viral protein corona directs viral pathogenesis and amyloid aggregation

(2019) Kariem Ezzat et al.   Nature Communications

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

(2018) William A. Eimer et al.   NEURON

Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

(2018) Ben Readhead et al.   NEURON

Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer’s Disease?

(2018) Tamas Fulop et al.   Frontiers in Aging Neuroscience

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Elucidating the Role of TREM2 in Alzheimer’s Disease

(2017) Jason D. Ulrich et al.   NEURON

TREM2, Microglia, and Neurodegenerative Diseases

(2017) Felix L. Yeh et al.   TRENDS IN MOLECULAR MEDICINE

The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis

(2017) Lindsay Kosack et al.   Scientific Reports

HHV-6A/6B Infection of NK Cells Modulates the Expression of miRNAs and Transcription Factors Potentially Associated to Impaired NK Activity

(2017) Roberta Rizzo et al.   Frontiers in Microbiology

Neuroinflammation in Alzheimer's disease: Current evidence and future directions

(2016) Valeria Calsolaro et al.   Alzheimers & Dementia

Isolation, Culture and Identification of Choriocarcinoma Stem-Like Cells from the Human Choriocarcinoma Cell-Line JEG-3

(2016) Jingting Cai et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model

(2016) Karine Bourgade et al.   JOURNAL OF ALZHEIMERS DISEASE

Anti-Viral Properties of Amyloid-β Peptides

(2016) Karine Bourgade et al.   JOURNAL OF ALZHEIMERS DISEASE

Presence of HHV-6A in Endometrial Epithelial Cells from Women with Primary Unexplained Infertility

(2016) Roberto Marci et al.   PLoS One

Activation of NOD1 by DAP contributes to myocardial ischemia/reperfusion injury via multiple signaling pathways

(2015) Hui Yang et al.   APOPTOSIS

Acute human herpesvirus-6A infection of human mesothelial cells modulates HLA molecules

(2015) Elisabetta Caselli et al.   ARCHIVES OF VIROLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Infection, systemic inflammation, and Alzheimer's disease

(2015) Siok Lam Lim et al.   MICROBES AND INFECTION

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

β-Amyloid peptides display protective activity against the human Alzheimer’s disease-associated herpes simplex virus-1

(2014) Karine Bourgade et al.   BIOGERONTOLOGY

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Classification of HHV-6A and HHV-6B as distinct viruses

(2013) Dharam Ablashi et al.   ARCHIVES OF VIROLOGY

Can Infections Cause Alzheimer's Disease?

(2013) F. Mawanda et al.   EPIDEMIOLOGIC REVIEWS

Herpes virus in Alzheimer's disease: relation to progression of the disease

(2013) Ilaria Carbone et al.   NEUROBIOLOGY OF AGING

Expression of Tau40 Induces Activation of Cultured Rat Microglial Cells

(2013) Lu Wang et al.   PLoS One

CD134 is a cellular receptor specific for human herpesvirus-6B entry

(2013) H. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer’s disease

(2013) B Parajuli et al.   Cell Death & Disease

Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression

(2013) Dan Frenkel et al.   Nature Communications

A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines

(2012) Jose Miguel Rubio-Perez et al.   TheScientificWorldJOURNAL

Virologic and Immunologic Evidence Supporting an Association between HHV-6 and Hashimoto's Thyroiditis

(2012) Elisabetta Caselli et al.   PLoS Pathogens

Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic Mice

(2011) Michael Sy et al.   AMERICAN JOURNAL OF PATHOLOGY

The molecular biology of human herpesvirus-6 latency and telomere integration

(2011) Jesse H. Arbuckle et al.   MICROBES AND INFECTION

Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils

(2011) Jan Bieschke et al.   Nature Chemical Biology

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Human herpesvirus-6 entry into the central nervous system through the olfactory pathway

(2011) E. Harberts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human herpesvirus 6A induces apoptosis of primary human fetal astrocytes via both caspase-dependent and -independent pathways

(2011) Bin Gu et al.   Virology Journal

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Fyn-Tau-Amyloid: A Toxic Triad

(2010) Christian Haass et al.   CELL

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

U94 of human herpesvirus 6 inhibits in vitro angiogenesis and lymphangiogenesis

(2009) A. Caruso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE