KIR2DS2/KIR2DL2/HLA-C1 Haplotype Is Associated with Alzheimer’s Disease: Implication for the Role of Herpesvirus Infections

A Pilot Trial of Lirilumab With or Without Azacitidine for Patients With Myelodysplastic Syndrome

(2018) Fevzi Firat Yalniz et al.   Clinical Lymphoma Myeloma & Leukemia

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

(2018) William A. Eimer et al.   NEURON

Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus

(2018) Ben Readhead et al.   NEURON

Anti-herpetic Medications and Reduced Risk of Dementia in Patients with Herpes Simplex Virus Infections—a Nationwide, Population-Based Cohort Study in Taiwan

(2018) Nian-Sheng Tzeng et al.   Neurotherapeutics

A phase 1 study of lirilumab (antibody against killer immunoglobulin-like receptor antibody KIR2D; IPH2102) in patients with solid tumors and hematologic malignancies

(2018) Norbert Vey et al.   Oncotarget

Molecular Mechanisms for Herpes Simplex Virus Type 1 Pathogenesis in Alzheimer’s Disease

(2018) Steven A. Harris et al.   Frontiers in Aging Neuroscience

Using Alzgene-Like Approaches to Investigate Susceptibility Genes for Vascular Cognitive Impairment

(2018) Rebecca Dwyer et al.   JOURNAL OF ALZHEIMERS DISEASE

Inflammatory and Neurodegeneration Markers during Asymptomatic HSV-1 Reactivation

(2018) Carolina Martin et al.   JOURNAL OF ALZHEIMERS DISEASE

HHV-6A Infection of Endometrial Epithelial Cells Induces Increased Endometrial NK Cell-Mediated Cytotoxicity

(2017) Elisabetta Caselli et al.   Frontiers in Microbiology

HHV-6A/6B Infection of NK Cells Modulates the Expression of miRNAs and Transcription Factors Potentially Associated to Impaired NK Activity

(2017) Roberta Rizzo et al.   Frontiers in Microbiology

Microbes and Alzheimer’s Disease

(2016) Ruth F. Itzhaki et al.   JOURNAL OF ALZHEIMERS DISEASE

KIR2DL2 inhibitory pathway enhances Th17 cytokine secretion by NK cells in response to herpesvirus infection in multiple sclerosis patients

(2016) Roberta Rizzo et al.   JOURNAL OF NEUROIMMUNOLOGY

Reactivated herpes simplex infection increases the risk of Alzheimer's disease

(2015) Hugo Lövheim et al.   Alzheimers & Dementia

Herpes Simplex Virus type-1 infection induces synaptic dysfunction in cultured cortical neurons via GSK-3 activation and intraneuronal amyloid-β protein accumulation

(2015) Roberto Piacentini et al.   Scientific Reports

APOE ε4: The most prevalent yet understudied risk factor for Alzheimer's disease

(2014) Daniel M. Michaelson   Alzheimers & Dementia

Classification of HHV-6A and HHV-6B as distinct viruses

(2013) Dharam Ablashi et al.   ARCHIVES OF VIROLOGY

Large Spectrum of HLA-C Recognition by Killer Ig-like Receptor (KIR)2DL2 and KIR2DL3 and Restricted C1 Specificity of KIR2DS2: Dominant Impact of KIR2DL2/KIR2DS2 on KIR2D NK Cell Repertoire Formation

(2013) G. David et al.   JOURNAL OF IMMUNOLOGY

Virological and Immunological Characteristics of Human Cytomegalovirus Infection Associated With Alzheimer Disease

(2013) Nell S. Lurain et al.   JOURNAL OF INFECTIOUS DISEASES

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94

(2013) K. S. Cheent et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NK cell MHC class I specific receptors (KIR): from biology to clinical intervention

(2012) Ariane Thielens et al.   CURRENT OPINION IN IMMUNOLOGY

Altered natural killer cells' response to herpes virus infection in multiple sclerosis involves KIR2DL2 expression

(2012) Roberta Rizzo et al.   JOURNAL OF NEUROIMMUNOLOGY

Virologic and Immunologic Evidence Supporting an Association between HHV-6 and Hashimoto's Thyroiditis

(2012) Elisabetta Caselli et al.   PLoS Pathogens

Herpes Simplex Virus Dances with Amyloid Precursor Protein while Exiting the Cell

(2011) Shi-Bin Cheng et al.   PLoS One

Antivirals Reduce the Formation of Key Alzheimer's Disease Molecules in Cell Cultures Acutely Infected with Herpes Simplex Virus Type 1

(2011) Matthew A. Wozniak et al.   PLoS One

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

EFNS guidelines for the diagnosis and management of Alzheimer’s disease

(2010) J. Hort et al.   EUROPEAN JOURNAL OF NEUROLOGY

Sp1 phosphorylation is involved in myelin basic protein gene transcription

(2010) Lili Guo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

APP Processing Induced by Herpes Simplex Virus Type 1 (HSV-1) Yields Several APP Fragments in Human and Rat Neuronal Cells

(2010) Giovanna De Chiara et al.   PLoS One

DNA methylation inhibition increases T cell KIR expression through effects on both promoter methylation and transcription factors

(2008) Ying Liu et al.   CLINICAL IMMUNOLOGY

Seropositivity to Herpes Simplex Virus Antibodies and Risk of Alzheimer's Disease: A Population-Based Cohort Study

(2008) Luc Letenneur et al.   PLoS One