Bergamot Polyphenols Improve Dyslipidemia and Pathophysiological Features in a Mouse Model of Non-Alcoholic Fatty Liver Disease

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

(2018) David Højland Ipsen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Case definitions for inclusion and analysis of endpoints in clinical trials for nonalcoholic steatohepatitis through the lens of regulatory science

(2018) Mohammad Shadab Siddiqui et al.   HEPATOLOGY

Analysis of proautophagic activities of Citrus flavonoids in liver cells reveals the superiority of a natural polyphenol mixture over pure flavones

(2018) Antonella Lascala et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence

(2018) Ahmed H. El-desoky et al.   PHYTOMEDICINE

PARP inhibition protects mitochondria and reduces ROS production via PARP-1-ATF4-MKP-1-MAPK retrograde pathway

(2017) Eniko Hocsak et al.   FREE RADICAL BIOLOGY AND MEDICINE

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease

(2017) Chris Estes et al.   HEPATOLOGY

The Mediterranean dietary pattern as the diet of choice for non-alcoholic fatty liver disease: Evidence and plausible mechanisms

(2017) Shira Zelber-Sagi et al.   LIVER INTERNATIONAL

Neohesperidin Exerts Lipid-Regulating Effects in vitro and in vivo via Fibroblast Growth Factor 21 and AMP-Activated Protein Kinase/Sirtuin Type 1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α Signaling Axis

(2017) Haoshu Wu et al.   PHARMACOLOGY

Mitogen-Activated Protein Kinase Regulation in Hepatic Metabolism

(2017) Ahmed Lawan et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Citrus bergamia powder: Antioxidant, antimicrobial and anti-inflammatory properties

(2017) Morena Gabriele et al.   Journal of Functional Foods

The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease

(2017) Sophie Cazanave et al.   Scientific Reports

A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer

(2016) Amon Asgharpour et al.   JOURNAL OF HEPATOLOGY

Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease

(2016) Manoela Mota et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Naringin ameliorates radiation-induced hepatic damage through modulation of Nrf2 and NF-κB pathways

(2016) Krishnendu Manna et al.   RSC Advances

Effect of a p38 MAPK inhibitor on FFA-induced hepatic insulin resistance in vivo

(2016) S Pereira et al.   Nutrition & Diabetes

Megestrol acetate improves cardiac function in a model of cancer cachexia-induced cardiomyopathy by autophagic modulation

(2016) Vincenzo Musolino et al.   Journal of Cachexia Sarcopenia and Muscle

Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: Findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop

(2015) Arun J. Sanyal et al.   HEPATOLOGY

Oxidized LDL attenuates protective autophagy and induces apoptotic cell death of endothelial cells: Role of oxidative stress and LOX-1 receptor expression

(2015) Vincenzo Mollace et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Pivotal role of liver sinusoidal endothelial cells in NAFLD/NASH progression

(2015) Masashi Miyao et al.   LABORATORY INVESTIGATION

Polyphenols and non-alcoholic fatty liver disease: impact and mechanisms

(2015) I. Rodriguez-Ramiro et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Quantitative Analysis of Histological Staining and Fluorescence Using ImageJ

(2014) Ellen C. Jensen   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

oxLDL induces injury and defenestration of human liver sinusoidal endothelial cells via LOX1

(2014) Qi Zhang et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Naringin Inhibits ROS-activated MAPK Pathway in High Glucose-induced Injuries in H9c2 Cardiac Cells

(2013) Jingfu Chen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis

(2013) Partha Mukhopadhyay et al.   HEPATOLOGY

Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia

(2013) Micaela Gliozzi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Naringin inhibits high glucose-induced cardiomyocyte apoptosis by attenuating mitochondrial dysfunction and modulating the activation of the p38 signaling pathway

(2013) HAILI HUANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Protective effects of sweet orange (Citrus sinensis) peel and their bioactive compounds on oxidative stress

(2012) Zong-Tsi Chen et al.   FOOD CHEMISTRY

Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients

(2012) Pierre Bedossa et al.   HEPATOLOGY

Hesperidin-mediated expression of Nrf2 and upregulation of antioxidant status in senescent rat heart

(2012) Jayasudha Elavarasan et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition

(2011) Michael Charlton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Saturated Fatty Acids Induce c-Src Clustering within Membrane Subdomains, Leading to JNK Activation

(2011) Ryan G. Holzer et al.   CELL

Frequency and Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis in the United States

(2011) Michael R. Charlton et al.   GASTROENTEROLOGY

p38 MAPK–mediated regulation of Xbp1s is crucial for glucose homeostasis

(2011) Jaemin Lee et al.   NATURE MEDICINE

Hypolipemic and hypoglycaemic activity of bergamot polyphenols: From animal models to human studies

(2010) Vincenzo Mollace et al.   FITOTERAPIA

On the Inhibitor Effects of Bergamot Juice Flavonoids Binding to the 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGR) Enzyme

(2010) Monica Leopoldini et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C

(2010) Carmelo García-Monzón et al.   JOURNAL OF HEPATOLOGY

Evaluation of Flavonoids and Furanocoumarins from Citrus bergamia (Bergamot) Juice and Identification of New Compounds

(2008) Claudio Gardana et al.   MOLECULES

Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

(2007) Puneet Puri et al.   GASTROENTEROLOGY