Differential immune response modulation in early Leishmania amazonensis infection of BALB/c and C57BL/6 macrophages based on transcriptome profiles

Melatonin and Leishmania amazonensis Infection Altered miR-294, miR-30e, and miR-302d Impacting on Tnf, Mcp-1, and Nos2 Expression

(2019) Juliane Cristina Ribeiro Fernandes et al.   Frontiers in Cellular and Infection Microbiology

Transcriptional Profiling of Immune-Related Genes in Leishmania infantum-Infected Mice: Identification of Potential Biomarkers of Infection and Progression of Disease

(2018) Eduardo Ontoria et al.   Frontiers in Cellular and Infection Microbiology

Biomarkers of Cutaneous Leishmaniasis

(2018) Fariborz Bahrami et al.   Frontiers in Cellular and Infection Microbiology

Arginine and Polyamines Fate in Leishmania Infection

(2018) Sandra M. Muxel et al.   Frontiers in Microbiology

Leishmaniasis

(2018) Sakib Burza et al.   LANCET

In Search of Biomarkers for Pathogenesis and Control of Leishmaniasis by Global Analyses of Leishmania-Infected Macrophages

(2018) Patricia Sampaio Tavares Veras et al.   Frontiers in Cellular and Infection Microbiology

Early Suppression of Macrophage Gene Expression by Leishmania braziliensis

(2018) Rosana Sousa et al.   Frontiers in Microbiology

How to master the host immune system? Leishmania parasites have the solutions!

(2017) Matteo Rossi et al.   INTERNATIONAL IMMUNOLOGY

Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis

(2017) Stephanie Maia Acuña et al.   PLoS One

RNA-seq transcriptional profiling of Leishmania amazonensis reveals an arginase-dependent gene expression regulation

(2017) Juliana Ide Aoki et al.   PLoS Neglected Tropical Diseases

L-arginine availability and arginase activity: Characterization of amino acid permease 3 in Leishmania amazonensis

(2017) Juliana Ide Aoki et al.   PLoS Neglected Tropical Diseases

Divergent roles for Ly6C+CCR2+CX3CR1+ inflammatory monocytes during primary or secondary infection of the skin with the intra-phagosomal pathogen Leishmania major

(2017) Audrey Romano et al.   PLoS Pathogens

Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype

(2017) Fanping Kong et al.   PLoS Pathogens

Treatment of Leishmania (Leishmania) Amazonensis-Infected Mice with a Combination of a Palladacycle Complex and Heat-Killed Propionibacterium acnes Triggers Protective Cellular Immune Responses

(2017) Carolina S. Paladi et al.   Frontiers in Microbiology

Leishmania (Leishmania) amazonensis induces macrophage miR-294 and miR-721 expression and modulates infection by targeting NOS2 and L-arginine metabolism

(2017) Sandra Marcia Muxel et al.   Scientific Reports

The NOD2 receptor is crucial for immune responses towards New World Leishmania species

(2017) Jéssica Cristina dos Santos et al.   Scientific Reports

Leishmania donovani inhibits macrophage apoptosis and pro-inflammatory response through AKT-mediated regulation of β-catenin and FOXO-1

(2016) Purnima Gupta et al.   CELL DEATH AND DIFFERENTIATION

The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice

(2016) Melanie Charmoy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NOD2-RIP2–Mediated Signaling Helps Shape Adaptive Immunity in Visceral Leishmaniasis

(2016) Manuela S. L. Nascimento et al.   JOURNAL OF INFECTIOUS DISEASES

New insights into the multidimensional concept of macrophage ontogeny, activation and function

(2016) Florent Ginhoux et al.   NATURE IMMUNOLOGY

Distinct courses of infection with Leishmania (L.) amazonensis are observed in BALB/c, BALB/c nude and C57BL/6 mice

(2016) LEONARDO G. VELASQUEZ et al.   PARASITOLOGY

Dual Transcriptome Profiling of Leishmania -Infected Human Macrophages Reveals Distinct Reprogramming Signatures

(2016) Maria Cecilia Fernandes et al.   mBio

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

(2016) Stephen M. Christensen et al.   PLoS Neglected Tropical Diseases

Simultaneous transcriptional profiling of Leishmania major and its murine macrophage host cell reveals insights into host-pathogen interactions

(2015) Laura A. L. Dillon et al.   BMC GENOMICS

Transcriptomic profiling of gene expression and RNA processing duringLeishmania majordifferentiation

(2015) Laura A. L. Dillon et al.   NUCLEIC ACIDS RESEARCH

Comparative Life Cycle Transcriptomics Revises Leishmania mexicana Genome Annotation and Links a Chromosome Duplication with Parasitism of Vertebrates

(2015) Michael Fiebig et al.   PLoS Pathogens

Systematic Review of Biomarkers To Monitor Therapeutic Response in Leishmaniasis

(2014) Anke E. Kip et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

CD4+ T Cells: Guardians of the Phagosome

(2014) N. J. Tubo et al.   CLINICAL MICROBIOLOGY REVIEWS

Site-Dependent Recruitment of Inflammatory Cells Determines the Effective Dose of Leishmania major

(2014) Flavia L. Ribeiro-Gomes et al.   INFECTION AND IMMUNITY

Release and activity of histone in diseases

(2014) R Chen et al.   Cell Death & Disease

FOXO Transcription Factors: Their Clinical Significance and Regulation

(2014) Yu Wang et al.   Biomed Research International

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

The transcriptome of Leishmania major in the axenic promastigote stage: transcript annotation and relative expression levels by RNA-seq

(2013) Alberto Rastrojo et al.   BMC GENOMICS

Characterization of murine macrophages from bone marrow, spleen and peritoneum

(2013) Changqi Wang et al.   BMC IMMUNOLOGY

Iron uptake controls the generation ofLeishmaniainfective forms through regulation of ROS levels

(2013) Bidyottam Mittra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammasome-derived IL-1β production induces nitric oxide–mediated resistance to Leishmania

(2013) Djalma S Lima-Junior et al.   NATURE MEDICINE

Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation

(2013) D DH Tran et al.   Cell Death & Disease

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

A comparison of two distinct murine macrophage gene expression profiles in response to Leishmania amazonensis infection

(2012) Christian M Probst et al.   BMC MICROBIOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Disease Severity in Patients Infected with Leishmania mexicana Relates to IL-1β

(2012) Edith A. Fernández-Figueroa et al.   PLoS Neglected Tropical Diseases

Human Macrophage Response to L. (Viannia) panamensis: Microarray Evidence for an Early Inflammatory Response

(2012) Carolina Ramírez et al.   PLoS Neglected Tropical Diseases

Redundant Notch1 and Notch2 Signaling Is Necessary for IFNγ Secretion by T Helper 1 Cells During Infection with Leishmania major

(2012) Floriane Auderset et al.   PLoS Pathogens

The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response

(2012) Dong Liu et al.   Frontiers in Cellular and Infection Microbiology

T Helper1/T Helper2 Cells and Resistance/Susceptibility to Leishmania Infection: Is This Paradigm Still Relevant?

(2012) James Alexander et al.   Frontiers in Immunology

Role of chemokines in regulation of immunity against leishmaniasis

(2010) Steve Oghumu et al.   EXPERIMENTAL PARASITOLOGY

Histopathological analysis of initial cellular response in TLR-2 deficient mice experimentally infected by Leishmania (L.) amazonensis

(2010) Camila Silva Guerra et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Efficacy of the tubercidin antileishmania action associated with an inhibitor of the nucleoside transport

(2008) J. I. Aoki et al.   PARASITOLOGY RESEARCH

The Neglected Tropical Diseases of Latin America and the Caribbean: A Review of Disease Burden and Distribution and a Roadmap for Control and Elimination

(2008) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases