Leishmania donovani inhibits macrophage apoptosis and pro-inflammatory response through AKT-mediated regulation of β-catenin and FOXO-1

Leishmania mexicanaamastigotes inhibit p38 and JNK and activate PI3K/AKT: role in the inhibition of apoptosis of dendritic cells

(2015) R. Vázquez-López et al.   PARASITE IMMUNOLOGY

Leishmania donovani targets tumor necrosis factor receptor-associated factor (TRAF) 3 for impairing TLR4-mediated host response

(2014) Purnima Gupta et al.   FASEB JOURNAL

Kinase AKT controls innate immune cell development and function

(2013) Yan Zhang et al.   IMMUNOLOGY

FOXO Transcription Factors Regulate Innate Immune Mechanisms in Respiratory Epithelial Cells

(2013) F. Seiler et al.   JOURNAL OF IMMUNOLOGY

LAB/NTAL Facilitates Fungal/PAMP-induced IL-12 and IFN-γ Production by Repressing β-Catenin Activation in Dendritic Cells

(2013) Selinda J. Orr et al.   PLoS Pathogens

PTEN-mediated akt/β-Catenin/foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury

(2012) Naoko Kamo et al.   HEPATOLOGY

Leishmania donovani Exploits Host Deubiquitinating Enzyme A20, a Negative Regulator of TLR Signaling, To Subvert Host Immune Response

(2012) S. Srivastav et al.   JOURNAL OF IMMUNOLOGY

Sleeping with the Enemy: How Intracellular Pathogens Cope with a Macrophage Lifestyle

(2012) Emily P. Thi et al.   PLoS Pathogens

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway

(2011) Taras T. Antoniv et al.   IMMUNOLOGY

Myeloid Cell IL-10 Production in Response to Leishmania Involves Inactivation of Glycogen Synthase Kinase-3  Downstream of Phosphatidylinositol-3 Kinase

(2011) D. Nandan et al.   JOURNAL OF IMMUNOLOGY

Activation of Phosphatidylinositol 3-Kinase/Akt and Impairment of Nuclear Factor-κB

(2010) Bruno Miguel Neves et al.   AMERICAN JOURNAL OF PATHOLOGY

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

(2010) WuQiang Fan et al.   EMBO JOURNAL

Uncoupling of Acetylation from Phosphorylation Regulates FoxO1 Function Independent of Its Subcellular Localization

(2010) Li Qiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LeishmaniaInterferes with Host Cell Signaling to Devise a Survival Strategy

(2010) Suvercha Bhardwaj et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

MAPK-directed phosphatases preferentially regulate pro- and anti-inflammatory cytokines in experimental visceral leishmaniasis: involvement of distinct protein kinase C isoforms

(2010) Susanta Kar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Trypanosoma cruzi Targets Akt in Host Cells as an Intracellular Antiapoptotic Strategy

(2009) M. V. Chuenkova et al.   Science Signaling

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Interaction of FOXO with β-Catenin Inhibits β-Catenin/T Cell Factor Activity

(2008) Diana Hoogeboom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Staying alive: bacterial inhibition of apoptosis during infection

(2008) Christina S. Faherty et al.   TRENDS IN MICROBIOLOGY