VAS2870 and VAS3947 attenuate platelet activation and thrombus formation via a NOX-independent pathway downstream of PKC

Regulation of platelet activation and thrombus formation by reactive oxygen species

(2018) Jianlin Qiao et al.   Redox Biology

Licochalcone A Prevents Platelet Activation and Thrombus Formation through the Inhibition of PLCγ2-PKC, Akt, and MAPK Pathways

(2017) Li-Ming Lien et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A novel flow cytometry assay using dihydroethidium as redox-sensitive probe reveals NADPH oxidase-dependent generation of superoxide anion in human platelets exposed to amyloid peptide β

(2017) Aisha Alsheikh Abubaker et al.   PLATELETS

NOX Activation by Subunit Interaction and Underlying Mechanisms in Disease

(2017) Radhika Rastogi et al.   Frontiers in Cellular Neuroscience

Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and ThrombosisSignificance

(2016) M. Keegan Delaney et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor

(2015) Kazufumi Hirano et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox-2 up-regulation and platelet activation: Novel insights

(2015) Daniele Pastori et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Platelet NOX, a novel target for anti-thrombotic treatment

(2014) Pasquale Pignatelli et al.   THROMBOSIS AND HAEMOSTASIS

Different Degrees of NADPH Oxidase 2 Regulation and In Vivo Platelet Activation: Lesson From Chronic Granulomatous Disease

(2014) Roberto Carnevale et al.   Journal of the American Heart Association

The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation

(2014) T.G. Walsh et al.   Redox Biology

Reactive Oxygen Species Play a Critical Role in Collagen-Induced Platelet Activation via SHP-2 Oxidation

(2013) Ji Yong Jang et al.   ANTIOXIDANTS & REDOX SIGNALING

Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo

(2013) Kuan H. Lin et al.   BIOCHEMICAL PHARMACOLOGY

I B kinase phosphorylation of SNAP-23 controls platelet secretion

(2013) Z. A. Karim et al.   BLOOD

Neuroprotection After Stroke by Targeting NOX4 As a Source of Oxidative Stress

(2012) Kim A. Radermacher et al.   ANTIOXIDANTS & REDOX SIGNALING

The novel NOX inhibitor 2-acetylphenothiazine impairs collagen-dependent thrombus formation in a GPVI-dependent manner

(2012) D Vara et al.   BRITISH JOURNAL OF PHARMACOLOGY

The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

(2012) Sebastian Altenhöfer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NOX1, 2, 4, 5: counting out oxidative stress

(2011) K Wingler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protein kinase C-theta in platelet activation

(2011) Sagit Cohen et al.   FEBS LETTERS

Platelet adhesion and activation mechanisms in arterial thrombosis and ischaemic stroke

(2011) B. NIESWANDT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery

(2010) Dennis A. Smith et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanisms of resveratrol-induced platelet apoptosis

(2009) K. H. Lin et al.   CARDIOVASCULAR RESEARCH

Platelet-derived growth factor BB stimulates vasculogenesis of embryonic stem cell-derived endothelial cells by calcium-mediated generation of reactive oxygen species

(2008) S. Lange et al.   CARDIOVASCULAR RESEARCH

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL