Copper-catalyzed enantioselective Sonogashira-type oxidative cross-coupling of unactivated C(sp3)−H bonds with alkynes

Copper-Catalyzed Remote C(sp3 )−H Trifluoromethylation of Carboxamides and Sulfonamides

(2019) Zhonglin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric, Nearly Barrierless C(sp3)–H Activation Promoted by Easily-Accessible N-Protected Aminosulfoxides as New Chiral Ligands

(2019) Soufyan Jerhaoui et al.   ACS Catalysis

Pd(II)-Catalyzed Enantioselective Alkynylation of Unbiased Methylene C(sp3)–H Bonds Using 3,3′-Fluorinated-BINOL as a Chiral Ligand

(2019) Ye-Qiang Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Arylation of Benzylic C-H bonds via Copper-Catalyzed Radical Relay

(2019) Guosheng Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective C-H Activation with Earth-Abundant 3d Transition Metals

(2019) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Acyclic Quaternary Carbon Stereocenters by Catalytic Asymmetric Hydroalkynylation of Unactivated Alkenes

(2019) Zi-Xuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carboamination of Unactivated Alkenes through Three-Component Radical Conjugate Addition

(2019) Heng Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amidyl Radicals by Oxidation of α-Amido-oxy Acids: Transition-Metal-Free Amidofluorination of Unactivated Alkenes

(2018) Heng Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Copper Catalyst with a Cinchona-Alkaloid-Based Sulfonamide Ligand for Asymmetric Radical Oxytrifluoromethylation of Alkenyl Oximes

(2018) Xi-Tao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

(Guanidine)copper Complex-Catalyzed Enantioselective Dynamic Kinetic Allylic Alkynylation under Biphasic Condition

(2018) Xi-Yang Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C(sp3)‒H bond activation by chiral transition metal catalysts

(2018) Tyler G. Saint-Denis et al.   SCIENCE

Remote C–H Functionalization via Selective Hydrogen Atom Transfer

(2018) David Nagib et al.   SYNTHESIS-STUTTGART

Remote C−H functionalization using radical translocating arylating groups

(2018) Florian W. Friese et al.   Nature Communications

Copper-Catalyzed Radical Relay for Asymmetric Radical Transformations

(2018) Fei Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Copper-Catalyzed Arylation of Remote C(sp3 )−H Bonds in Carboxamides and Sulfonamides

(2018) Zhaodong Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Trifluoromethylalkynylation of Alkenes via Copper-Catalyzed Radical Relay

(2018) Liang Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu/Chiral Phosphoric Acid-Catalyzed Asymmetric Three-Component Radical-Initiated 1,2-Dicarbofunctionalization of Alkenes

(2018) Jin-Shun Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Synthesis of Propargyl Amides through Rh-Catalyzed Asymmetric Hydroalkynylation of Enamides: Scope, Mechanism, and Origin of Selectivity

(2017) Xiao-Yan Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regio- and Stereospecific Copper-Catalyzed Substitution Reaction of Propargylic Ammonium Salts with Aryl Grignard Reagents

(2017) Manuel Guisán-Ceinos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition metal–catalyzed alkyl-alkyl bond formation: Another dimension in cross-coupling chemistry

(2017) Junwon Choi et al.   SCIENCE

Formation of α-chiral centers by asymmetric β-C(sp 3 )–H arylation, alkenylation, and alkynylation

(2017) Qing-Feng Wu et al.   SCIENCE

Recent Progress of Transition-Metal-Catalyzed Enantioselective Hydroalkynylation of Alkenes

(2017) Bi-Jie Li et al.   SYNLETT

Photochemical Generation of Nitrogen-Centered Amidyl, Hydrazonyl, and Imidyl Radicals: Methodology Developments and Catalytic Applications

(2017) Markus D. Kärkäs   ACS Catalysis

Asymmetric Aerobic Oxidative Cross-Coupling of Tetrahydroisoquinolines with Alkynes

(2017) Tianyu Huang et al.   ACS Catalysis

Transition-Metal Catalysis of Nucleophilic Substitution Reactions: A Radical Alternative to SN1 and SN2 Processes

(2017) Gregory C. Fu   ACS Central Science

Iridium-Catalyzed Enantioselective Hydroalkynylation of Enamides for the Synthesis of Homopropargyl Amides

(2016) Xiao-Yan Bai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper/Guanidine-Catalyzed Asymmetric Alkynylation of Isatins

(2016) Quangang Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Enantioselective C(sp3 )−H Functionalization

(2016) Qingquan Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New amination strategies based on nitrogen-centered radical chemistry

(2016) Tao Xiong et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Amides with Remote Stereocenters by Catalytic Asymmetric γ-Alkynylation of α,β-Unsaturated Amides

(2016) Zi-Xuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed, Fluoroamide-Directed C–H Fluorination

(2016) Brian J. Groendyke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Dual-Catalytic Strategy To Direct Asymmetric Radical Aminotrifluoromethylation of Alkenes

(2016) Jin-Shun Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Aerobic Enantioselective Cross-Dehydrogenative Coupling of N-Aryl Glycine Esters with Terminal Alkynes

(2016) Zhiyu Xie et al.   ORGANIC LETTERS

Enantioselective cyanation of benzylic C–H bonds via copper-catalyzed radical relay

(2016) Wen Zhang et al.   SCIENCE

Efficient merging of copper and photoredox catalysis for the asymmetric cross-dehydrogenative-coupling of alkynes and tetrahydroisoquinolines

(2015) Inna Perepichka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Catalytic Cross-Dehydrogenative Coupling of N-Carbamoyl Tetrahydroisoquinolines and Terminal Alkynes

(2015) Shutao Sun et al.   ORGANIC LETTERS

Enantioselective CH Bond Functionalization Triggered by Radical Trifluoromethylation of Unactivated Alkene

(2014) Peng Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Enantioselective Allylic Alkylation of Terminal Alkyne Pronucleophiles

(2014) Ayumi Harada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Stereoretentive Olefination of Unactivated C(sp3)–H Bonds with Vinyl Iodides at Room Temperature: Synthesis of β-Vinyl α-Amino Acids

(2014) Bo Wang et al.   ORGANIC LETTERS

The Cross-Dehydrogenative Coupling of C sp 3H Bonds: A Versatile Strategy for CC Bond Formations

(2013) Simon A. Girard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(0)-Catalyzed Alkynylation of C(sp3)–H Bonds

(2013) Jian He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition-Metal Complexes

(2012) Eric M. Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cinchona Alkaloid Amides/Dialkylzinc Catalyzed Enantioselective Desymmetrization of Aziridines with Phosphites

(2012) Masashi Hayashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Direct Ethynylation of C(sp3)–H Bonds in Aliphatic Carboxylic Acid Derivatives

(2011) Yusuke Ano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Family of Cinchona-Derived Amino Phosphine Precatalysts: Application to the Highly Enantio- and Diastereoselective Silver-Catalyzed Isocyanoacetate Aldol Reaction

(2011) Filippo Sladojevich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Alkyne-Substituted Quaternary Carbon Stereogenic Centers through NHC−Cu-Catalyzed Allylic Substitution Reactions with (i-Bu)2(Alkynyl)aluminum Reagents

(2011) Jennifer A. Dabrowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of eudesmane terpenes by site-selective C–H oxidations

(2009) Ke Chen et al.   NATURE

Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations

(2008) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

Efficient Oxidative Alkyne Homocoupling Catalyzed by a Monomeric Dicopper-Substituted Silicotungstate

(2008) Keigo Kamata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1,3-Diol Synthesis via Controlled, Radical-Mediated C−H Functionalization

(2008) Ke Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Nickel-Catalyzed Cross-Coupling Reactions of Trialkynylindium Reagents with Racemic Secondary Benzyl Bromides

(2007) Jorge Caeiro et al.   CHEMISTRY-A EUROPEAN JOURNAL