CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG

Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors

(2018) Catherine J. Drummond et al.   CANCER CELL

Downregulation of castor zinc finger 1 predicts poor prognosis and facilitates hepatocellular carcinoma progression via MAPK/ERK signaling

(2018) Ji-Long Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma

(2018) Marielle E. Yohe et al.   Science Translational Medicine

PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis

(2018) Genevieve C Kendall et al.   eLife

Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity

(2018) Natarajan Bhaskaran et al.   Frontiers in Immunology

Human papillomavirus and the landscape of secondary genetic alterations in oral cancers

(2018) Maura L. Gillison et al.   GENOME RESEARCH

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

(2017) M Ryan Corces et al.   NATURE METHODS

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo

(2017) Shilpy Joshi et al.   PLoS Genetics

CASZ1 loss-of-function mutation associated with congenital heart disease

(2016) Ri-Tai Huang et al.   GENE

Models of human core transcriptional regulatory circuitries

(2016) Violaine Saint-André et al.   GENOME RESEARCH

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

(2016) Charles Y. Lin et al.   NATURE

Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma

(2016) Z Liu et al.   ONCOGENE

Neuronal cell fate diversification controlled by sub-temporal action of Kruppel

(2016) Johannes Stratmann et al.   eLife

Re-utilization of a transcription factor

(2016) Filipe Pinto-Teixeira et al.   eLife

A Conserved Regulatory Logic Controls Temporal Identity in Mouse Neural Progenitors

(2015) Pierre Mattar et al.   NEURON

ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases

(2014) Li Shen et al.   BMC GENOMICS

The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation

(2014) Annie M. Tremblay et al.   CANCER CELL

Differential regulation of CASZ1 protein expression during cardiac and skeletal muscle development

(2014) Nirav M. Amin et al.   DEVELOPMENTAL DYNAMICS

Essential Role of the Zinc Finger Transcription Factor Casz1 for Mammalian Cardiac Morphogenesis and Development

(2014) Zhihui Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors

(2014) J. F. Shern et al.   Cancer Discovery

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

CASZ1 inhibits cell cycle progression in neuroblastoma by restoring pRb activity

(2013) Zhihui Liu et al.   CELL CYCLE

Mechanisms of impaired differentiation in rhabdomyosarcoma

(2013) Charles Keller et al.   FEBS Journal

Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cells

(2013) Meiling Zhang et al.   Molecular Cancer

Large-Scale Quality Analysis of Published ChIP-seq Data

(2013) Georgi K. Marinov et al.   G3-Genes Genomes Genetics

A Mouse Model of Rhabdomyosarcoma Originating from the Adipocyte Lineage

(2012) Mark E. Hatley et al.   CANCER CELL

Myoblast fusion: lessons from flies and mice

(2012) S. M. Abmayr et al.   DEVELOPMENT

Genome-wide identification of enhancers in skeletal muscle: the role of MyoD1

(2012) R. Blum et al.   GENES & DEVELOPMENT

Loss of gene function as a consequence of human papillomavirus DNA integration

(2012) Martina Schmitz et al.   INTERNATIONAL JOURNAL OF CANCER

Characterization of Critical Domains within the Tumor Suppressor CASZ1 Required for Transcriptional Regulation and Growth Suppression

(2012) R. A. Virden et al.   MOLECULAR AND CELLULAR BIOLOGY

Snail Regulates MyoD Binding-Site Occupancy to Direct Enhancer Switching and Differentiation-Specific Transcription in Myogenesis

(2012) Vahab D. Soleimani et al.   MOLECULAR CELL

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Building Muscle: Molecular Regulation of Myogenesis

(2012) C. F. Bentzinger et al.   Cold Spring Harbor Perspectives in Biology

miR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells

(2012) Kyle L MacQuarrie et al.   Skeletal Muscle

Evidence for an Unanticipated Relationship between Undifferentiated Pleomorphic Sarcoma and Embryonal Rhabdomyosarcoma

(2011) Brian P. Rubin et al.   CANCER CELL

EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR

(2011) C. Wang et al.   CANCER RESEARCH

CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression

(2011) Z Liu et al.   CELL DEATH AND DIFFERENTIATION

CASZ1b, the Short Isoform of CASZ1 Gene, Coexpresses with CASZ1a during Neurogenesis and Suppresses Neuroblastoma Cell Growth

(2011) Zhihui Liu et al.   PLoS One

Muscling in: Uncovering the origins of rhabdomyosarcoma

(2010) Simone Hettmer et al.   NATURE MEDICINE

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Opposing control of rhabdomyosarcoma growth and differentiation by myogenin and interleukin 4

(2009) P. Nanni et al.   MOLECULAR CANCER THERAPEUTICS

Pdm and Castor close successive temporal identity windows in the NB3-1 lineage

(2008) K. D. Tran et al.   DEVELOPMENT

Vertebrate CASTOR Is Required for Differentiation of Cardiac Precursor Cells at the Ventral Midline

(2008) Kathleen S. Christine et al.   DEVELOPMENTAL CELL