Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma

A Conserved Regulatory Logic Controls Temporal Identity in Mouse Neural Progenitors

(2015) Pierre Mattar et al.   NEURON

Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein

(2015) Jo Ishizawa et al.   PHARMACOLOGY & THERAPEUTICS

Zinc finger transcription factor CASZ1 interacts with histones, DNA repair proteins and recruits NuRD complex to regulate gene transcription

(2015) Zhihui Liu et al.   Oncotarget

Prediction of nuclear export signals using weighted regular expressions (Wregex)

(2014) Gorka Prieto et al.   BIOINFORMATICS

Essential Role of the Zinc Finger Transcription Factor Casz1 for Mammalian Cardiac Morphogenesis and Development

(2014) Zhihui Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SINE (selective inhibitor of nuclear export) – translational science in a new class of anti-cancer agents

(2014) John Gerecitano   Journal of Hematology & Oncology

The IKAROS Interaction with a Complex Including Chromatin Remodeling and Transcription Elongation Activities Is Required for Hematopoiesis

(2014) Stefania Bottardi et al.   PLoS Genetics

CASZ1 Promotes Vascular Assembly and Morphogenesis through the Direct Regulation of an EGFL7/RhoA-Mediated Pathway

(2013) Marta S. Charpentier et al.   DEVELOPMENTAL CELL

Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia

(2012) P. Ranganathan et al.   BLOOD

1p36 Tumor Suppression--A Matter of Dosage?

(2012) K.-O. Henrich et al.   CANCER RESEARCH

Loss of gene function as a consequence of human papillomavirus DNA integration

(2012) Martina Schmitz et al.   INTERNATIONAL JOURNAL OF CANCER

Characterization of Critical Domains within the Tumor Suppressor CASZ1 Required for Transcriptional Regulation and Growth Suppression

(2012) R. A. Virden et al.   MOLECULAR AND CELLULAR BIOLOGY

CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity

(2011) K. Sakakibara et al.   BLOOD

EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR

(2011) C. Wang et al.   CANCER RESEARCH

p53-Dependent BRCA1 Nuclear Export Controls Cellular Susceptibility to DNA Damage

(2011) J. Jiang et al.   CANCER RESEARCH

CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression

(2011) Z Liu et al.   CELL DEATH AND DIFFERENTIATION

CASZ1b, the Short Isoform of CASZ1 Gene, Coexpresses with CASZ1a during Neurogenesis and Suppresses Neuroblastoma Cell Growth

(2011) Zhihui Liu et al.   PLoS One

Blood Pressure and Hypertension Are Associated With 7 Loci in the Japanese Population

(2010) Fumihiko Takeuchi et al.   CIRCULATION

PARP-1 Regulates Chromatin Structure and Transcription through a KDM5B-Dependent Pathway

(2010) Raga Krishnakumar et al.   MOLECULAR CELL

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

Functional consequences of genetic variation in primates on tyrosine hydroxylase (TH) expression in vitro

(2009) Lisa R. Warner et al.   BRAIN RESEARCH

Identification of Nuclear Export Inhibitors with Potent Anticancer Activity In vivo

(2009) S. C. Mutka et al.   CANCER RESEARCH

Shuttling of SOX proteins

(2009) Safia Malki et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Clusterin, a Haploinsufficient Tumor Suppressor Gene in Neuroblastomas

(2009) Olesya Chayka et al.   JNCI-Journal of the National Cancer Institute

The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cellsin vivo

(2008) Johannes H. Schulte et al.   INTERNATIONAL JOURNAL OF CANCER

The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report

(2008) Susan L. Cohn et al.   JOURNAL OF CLINICAL ONCOLOGY

Neural cell adhesion molecule (NCAM) isoform expression is associated with neuroblastoma differentiation status

(2008) Cynthia Winter et al.   PEDIATRIC BLOOD & CANCER