Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

(2020) Sonia Shah et al.   Nature Communications

Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

(2019) Krishna G. Aragam et al.   CIRCULATION

CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing

(2019) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

WashU Epigenome Browser update 2019

(2019) Daofeng Li et al.   NUCLEIC ACIDS RESEARCH

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

(2019) Pablo Cordero et al.   Nature Communications

A global overview of pleiotropy and genetic architecture in complex traits

(2019) Kyoko Watanabe et al.   NATURE GENETICS

Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells

(2019) Yanxiao Zhang et al.   NATURE GENETICS

Cost-of-illness studies in heart failure: a systematic review 2004–2016

(2018) Wladimir Lesyuk et al.   BMC Cardiovascular Disorders

Multi-ethnic genome-wide association study for atrial fibrillation

(2018) Carolina Roselli et al.   NATURE GENETICS

Publisher Correction: The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma

(2018) Gaetana Restivo et al.   Nature Communications

Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy

(2018) Ameya R. Kirtane et al.   Nature Communications

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

A Swedish Nationwide Adoption Study of the Heritability of Heart Failure

(2018) Magnus P. Lindgren et al.   JAMA Cardiology

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

(2018) Jonas B. Nielsen et al.   NATURE GENETICS

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

(2018) Wei Zhou et al.   NATURE GENETICS

Cell-Surface Marker Signature for Enrichment of Ventricular Cardiomyocytes Derived from Human Embryonic Stem Cells

(2018) Jennifer Veevers et al.   Stem Cell Reports

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

(2017) Philipp S. Wild et al.   JOURNAL OF CLINICAL INVESTIGATION

Erratum: Genetic effects on gene expression across human tissues

(2017)   NATURE

Annotation-free quantification of RNA splicing using LeafCutter

(2017) Yang I. Li et al.   NATURE GENETICS

Use of a neonatal rat system as a bioincubator to generate adult-like mature cardiomyocytes from human and mouse pluripotent stem cells

(2017) Gun-Sik Cho et al.   Nature Protocols

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

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(2016) Sayantan Das et al.   NATURE GENETICS

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(2015) Halit Ongen et al.   BIOINFORMATICS

The intriguing relationship between the ABO blood group, cardiovascular disease, and cancer

(2015) Massimo Franchini et al.   BMC Medicine

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Universal Cardiac Induction of Human Pluripotent Stem Cells in Two and Three-Dimensional Formats: Implications for In Vitro Maturation

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Second-generation PLINK: rising to the challenge of larger and richer datasets

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A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

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Identifying Causal Variants at Loci with Multiple Signals of Association

(2014) F. Hormozdiari et al.   GENETICS

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Imputation and quality control steps for combining multiple genome-wide datasets

(2014) Shefali S. Verma et al.   Frontiers in Genetics

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(2013) Véronique L. Roger   CIRCULATION RESEARCH

The epidemiology of heart failure, based on data for 2.1 million inhabitants in Sweden

(2013) Ramin Zarrinkoub et al.   EUROPEAN JOURNAL OF HEART FAILURE

ABO Blood Group and Risk of Coronary Heart Disease in Two Prospective Cohort Studies

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(2012) A. A. Shabalin   BIOINFORMATICS

A high-performance computing toolset for relatedness and principal component analysis of SNP data

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Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes

(2012) Shugo Tohyama et al.   Cell Stem Cell

α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms

(2012) Vandana Gupta et al.   FASEB JOURNAL

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

(2012) Xiaojun Lian et al.   Nature Protocols

Large-scale discovery of enhancers from human heart tissue

(2011) Dalit May et al.   NATURE GENETICS

LocusZoom: regional visualization of genome-wide association scan results

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METAL: fast and efficient meta-analysis of genomewide association scans

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Mutations in Alpha-Actinin-2 Cause Hypertrophic Cardiomyopathy

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