Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 10, Issue 12, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-12-20
DOI
10.1038/s41419-019-2195-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- FoxM1-dependent RAD51 and BRCA2 signaling protects idiopathic pulmonary fibrosis fibroblasts from radiation-induced cell death
- (2018) Jintaek Im et al. Cell Death & Disease
- Macrophages in radiation injury: a new therapeutic target
- (2018) Lydia Meziani et al. OncoImmunology
- Andrographolide simultaneously augments Nrf2 antioxidant defense and facilitates autophagic flux blockade in cigarette smoke-exposed human bronchial epithelial cells
- (2018) W.S. Daniel Tan et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
- (2017) Jianjin Shi et al. TRENDS IN BIOCHEMICAL SCIENCES
- NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages
- (2017) Yan-gang Liu et al. Cell Death & Disease
- Diptoindonesin G promotes ERK-mediated nuclear translocation of p-STAT1 (Ser727) and cell differentiation in AML cells
- (2017) Jian Gao et al. Cell Death & Disease
- Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis
- (2017) Wenjie Guo et al. Nature Communications
- Immunological Aspect of Radiation-Induced Pneumonitis, Current Treatment Strategies, and Future Prospects
- (2017) Anup Kainthola et al. Frontiers in Immunology
- Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression
- (2016) Weicheng Wang et al. BIOCHEMICAL PHARMACOLOGY
- The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury
- (2016) Bo Hu et al. SCIENCE
- Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways
- (2016) Shuang Peng et al. Acta Pharmaceutica Sinica B
- Regulation of inflammasome activation
- (2015) Si Ming Man et al. IMMUNOLOGICAL REVIEWS
- Inhibition of Radiation-Induced Oxidative Damage in the Lung Tissue: May Acetylsalicylic Acid Have a Positive Role?
- (2015) Can Demirel et al. INFLAMMATION
- Inflammation and Pyroptosis Mediate Muscle Expansion in an Interleukin-1β (IL-1β)-dependent Manner
- (2015) Subhash Haldar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impact of Pretreatment Interstitial Lung Disease on Radiation Pneumonitis and Survival after Stereotactic Body Radiation Therapy for Lung Cancer
- (2015) Nami Ueki et al. Journal of Thoracic Oncology
- Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study
- (2015) Jeffrey D Bradley et al. LANCET ONCOLOGY
- Hypofractionated versus conventionally fractionated radiotherapy for patients with prostate cancer (HYPRO): acute toxicity results from a randomised non-inferiority phase 3 trial
- (2015) Shafak Aluwini et al. LANCET ONCOLOGY
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Mechanisms of inflammasome activation: recent advances and novel insights
- (2015) Sivapriya K. Vanaja et al. TRENDS IN CELL BIOLOGY
- Transforming growth factor-beta-1 is a serum biomarker of radiation-induced pneumonitis in esophageal cancer patients treated with thoracic radiotherapy: preliminary results of a prospective study
- (2015) Jingxia Li et al. OncoTargets and Therapy
- Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer
- (2014) Wenjie Guo et al. Autophagy
- Mechanisms and Functions of Inflammasomes
- (2014) Mohamed Lamkanfi et al. CELL
- Andrographolide sulfonate ameliorates experimental colitis in mice by inhibiting Th1/Th17 response
- (2014) Wen Liu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Frontiers in Radiotherapy for Early-Stage Invasive Breast Cancer
- (2014) Christine M. Fisher et al. JOURNAL OF CLINICAL ONCOLOGY
- Radiotherapy for renal-cell carcinoma
- (2014) Gert De Meerleer et al. LANCET ONCOLOGY
- Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis
- (2013) Nian-Hua Ding et al. CURRENT DRUG TARGETS
- Constitutive and tumor necrosis factor-α-induced activation of nuclear factor-κB in adenomyosis and its inhibition by andrographolide
- (2013) Bin Li et al. FERTILITY AND STERILITY
- Transforming Growth Factor β-1 (TGF-β1) Is a Serum Biomarker of Radiation Induced Fibrosis in Patients Treated With Intracavitary Accelerated Partial Breast Irradiation: Preliminary Results of a Prospective Study
- (2013) Dustin L. Boothe et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Water-soluble andrographolide sulfonate exerts anti-sepsis action in mice through down-regulating p38 MAPK, STAT3 and NF-κB pathways
- (2012) Wenjie Guo et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Prediction of radiation pneumonitis in lung cancer patients: a systematic review
- (2012) Xiao-Jing Zhang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Inflammasomes in health and disease
- (2012) Till Strowig et al. NATURE
- Regulation of inflammasome signaling
- (2012) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- Blockade of lysophosphatidic acid receptors LPAR1/3 ameliorates lung fibrosis induced by irradiation
- (2011) Lu Gan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment
- (2010) G.-O. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Novel Antiinflammatory Role for Andrographolide in Asthma via Inhibition of the Nuclear Factor-κB Pathway
- (2009) Zhang Bao et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis
- (2009) D. G. Kirsch et al. SCIENCE
- PUMA Regulates Intestinal Progenitor Cell Radiosensitivity and Gastrointestinal Syndrome
- (2008) Wei Qiu et al. Cell Stem Cell
- In vitro and in vivo anti-inflammatory effects of andrographolide
- (2008) Ala'a A. Abu-Ghefreh et al. INTERNATIONAL IMMUNOPHARMACOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now