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CircScd1 Promotes Fatty Liver Disease via the Janus Kinase 2/Signal Transducer and Activator of Transcription 5 Pathway

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Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues

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Fibrosis stage but not NASH predicts mortality and time to development of severe liver disease in biopsy-proven NAFLD

(2017) Hannes Hagström et al.   JOURNAL OF HEPATOLOGY

Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress

(2017) Carlos Maillo et al.   NATURE CELL BIOLOGY

circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis

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Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease

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CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy

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ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells

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An In Vivo Method to Identify microRNA Targets Not Predicted by Computation Algorithms: p21 Targeting by miR-92a in Cancer

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miR-122 – A key factor and therapeutic target in liver disease

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The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells

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ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis

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The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

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Autophagy and Non-Alcoholic Fatty Liver Disease

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Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

A Circuitous Route to Noncoding RNA

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MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

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(2012) Gyongyi Szabo et al.   JOURNAL OF HEPATOLOGY

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

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(2011) Muhammad Amir et al.   Expert Review of Gastroenterology & Hepatology

Quantitation of "autophagic flux" in mature skeletal muscle

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HDMCP uncouples yeast mitochondrial respiration and alleviates steatosis in L02 and hepG2 cells by decreasing ATP and H2O2 levels: A novel mechanism for NAFLD

(2009) Xi Jin et al.   JOURNAL OF HEPATOLOGY

Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression

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