Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress

Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease

(2016) Vittorio Calderone et al.   GASTROENTEROLOGY

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism

(2016) Céline Jouffe et al.   Scientific Reports

Lipid-dependent regulation of the unfolded protein response

(2015) Romain Volmer et al.   CURRENT OPINION IN CELL BIOLOGY

The BioMart community portal: an innovative alternative to large, centralized data repositories

(2015) Damian Smedley et al.   NUCLEIC ACIDS RESEARCH

Comprehensive translational control of tyrosine kinase expression by upstream open reading frames

(2015) K Wethmar et al.   ONCOGENE

Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle

(2015) Valeria Giangarrà et al.   PLoS One

A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

(2015) M. Mohrin et al.   SCIENCE

Discrete functions of nuclear receptor Rev-erb  couple metabolism to the clock

(2015) Y. Zhang et al.   SCIENCE

Changes in poly(A) tail length dynamics from the loss of the circadian deadenylase Nocturnin

(2015) Shihoko Kojima et al.   Scientific Reports

SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3

(2015) Bettina Drisaldi et al.   Cell Reports

Cytoplasmic Polyadenylation Element Binding Proteins in Development, Health, and Disease

(2014) Maria Ivshina et al.   Annual Review of Cell and Developmental Biology

ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development

(2014) Hayato Nakagawa et al.   CANCER CELL

The Unfolded Protein Response Triggers Selective mRNA Release from the Endoplasmic Reticulum

(2014) David W. Reid et al.   CELL

How does protein misfolding in the endoplasmic reticulum affect lipid metabolism in the liver?

(2014) Shiyu Wang et al.   CURRENT OPINION IN LIPIDOLOGY

Cpeb4-Mediated Translational Regulatory Circuitry Controls Terminal Erythroid Differentiation

(2014) Wenqian Hu et al.   DEVELOPMENTAL CELL

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins

(2014) T. Afroz et al.   GENES & DEVELOPMENT

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress

(2014) Peter van Galen et al.   NATURE

Quantitative profiling of initiating ribosomes in vivo

(2014) Xiangwei Gao et al.   NATURE METHODS

Integration of UPRER and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation

(2014) Lifen Wang et al.   PLoS Genetics

CPEB1 coordinates alternative 3′-UTR formation with translational regulation

(2013) Felice-Alessio Bava et al.   NATURE

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver

(2013) D. Mauvoisin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The CPEB-family of proteins, translational control in senescence and cancer

(2012) Gonzalo Fernández-Miranda et al.   AGEING RESEARCH REVIEWS

Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression

(2012) S. Kojima et al.   GENES & DEVELOPMENT

Lipolysis Response to Endoplasmic Reticulum Stress in Adipose Cells

(2012) Jingna Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Translational control by changes in poly(A) tail length: recycling mRNAs

(2012) Laure Weill et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ePAT: A simple method to tag adenylated RNA to measure poly(A)-tail length and other 3' RACE applications

(2012) A. Janicke et al.   RNA

Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance

(2012) Ilya M. Alexandrov et al.   PLoS Genetics

htSeqTools: high-throughput sequencing quality control, processing and visualization in R

(2011) Evarist Planet et al.   BIOINFORMATICS

Neuralized1 Activates CPEB3: A Function for Nonproteolytic Ubiquitin in Synaptic Plasticity and Memory Storage

(2011) Elias Pavlopoulos et al.   CELL

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Key contribution of CPEB4-mediated translational control to cancer progression

(2011) Elena Ortiz-Zapater et al.   NATURE MEDICINE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Circadian Clock-Coordinated 12 Hr Period Rhythmic Activation of the IRE1α Pathway Controls Lipid Metabolism in Mouse Liver

(2010) Gaspard Cretenet et al.   Cell Metabolism

Meiosis requires a translational positive loop where CPEB1 ensues its replacement by CPEB4

(2010) Ana Igea et al.   EMBO JOURNAL

CPEB4 Is a Cell Survival Protein Retained in the Nucleus upon Ischemia or Endoplasmic Reticulum Calcium Depletion

(2010) M.-C. Kan et al.   MOLECULAR AND CELLULAR BIOLOGY

Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications

(2009) Elisa Fabbrini et al.   HEPATOLOGY

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression

(2009) Christopher Vollmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Combinatorial Code for CPE-Mediated Translational Control

(2008) Maria Piqué et al.   CELL

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation

(2008) D. M. Burns et al.   GENES & DEVELOPMENT

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

(2008) Tsuguhito Ota et al.   JOURNAL OF CLINICAL INVESTIGATION

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

(2008) Catherine Postic et al.   JOURNAL OF CLINICAL INVESTIGATION

A deadenylation negative feedback mechanism governs meiotic metaphase arrest

(2008) Eulàlia Belloc et al.   NATURE