Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

Packaging and Prefusion Stabilization Separately and Additively Increase the Quantity and Quality of Respiratory Syncytial Virus (RSV)-Neutralizing Antibodies Induced by an RSV Fusion Protein Expressed by a Parainfluenza Virus Vector

(2016) Bo Liang et al.   JOURNAL OF VIROLOGY

Is There an Optimal Formulation and Delivery Strategy for Subunit Vaccines?

(2016) Sharan Bobbala et al.   PHARMACEUTICAL RESEARCH

A first-in-human phase 1 trial to evaluate the safety and immunogenicity of the candidate tuberculosis vaccine MVA85A-IMX313, administered to BCG-vaccinated adults

(2016) Alice Minhinnick et al.   VACCINE

Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay

(2016) Kazutoyo Miura et al.   VACCINE

A Modular Vaccine Development Platform Based on Sortase-Mediated Site-Specific Tagging of Antigens onto Virus-Like Particles

(2016) Shubing Tang et al.   Scientific Reports

Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

(2016) Stefan W. Metz et al.   PLoS Neglected Tropical Diseases

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

(2016) Susan Thrane et al.   JOURNAL OF NANOBIOTECHNOLOGY

Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

(2016) Yuanyuan Li et al.   Scientific Reports

Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

(2016) Karl D. Brune et al.   Scientific Reports

Feasibility of Cowpea chlorotic mottle virus-like particles as scaffold for epitope presentations

(2015) Afshin Hassani-Mehraban et al.   BMC BIOTECHNOLOGY

Secrets of a covalent interaction for biomaterials and biotechnology: SpyTag and SpyCatcher

(2015) Samuel C Reddington et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

His-tagged norovirus-like particles: A versatile platform for cellular delivery and surface display

(2015) Tiia Koho et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Toward the development of effective transmission-blocking vaccines for malaria

(2015) Daria Nikolaeva et al.   Expert Review of Vaccines

Anti-nicotine vaccines: Comparison of adjuvanted CRM 197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates

(2015) Michael J. McCluskie et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA

(2015) Susan Thrane et al.   PLoS One

Quality and quantity of T FH cells are critical for broad antibody development in SHIV AD8 infection

(2015) Takuya Yamamoto et al.   Science Translational Medicine

Head-to-Head Comparison of Soluble vs. Qβ VLP Circumsporozoite Protein Vaccines Reveals Selective Enhancement of NANP Repeat Responses

(2015) Farhat Khan et al.   PLoS One

Comparative Assessment of Transmission-Blocking Vaccine Candidates against Plasmodium falciparum

(2015) M. C. Kapulu et al.   Scientific Reports

Complement Inhibitor C4b-Binding Protein Interacts Directly with Small Glycoproteins of the Extracellular Matrix

(2014) K. E. Happonen et al.   JOURNAL OF IMMUNOLOGY

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers

(2014) Jenny G.H. Low et al.   VACCINE

Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes

(2014) Gunther Spohn et al.   Molecular Therapy-Methods & Clinical Development

Qualification of Standard Membrane-Feeding Assay with Plasmodium falciparum Malaria and Potential Improvements for Future Assays

(2013) Kazutoyo Miura et al.   PLoS One

A Plant-Produced Pfs25 VLP Malaria Vaccine Candidate Induces Persistent Transmission Blocking Antibodies against Plasmodium falciparum in Immunized Mice

(2013) R. Mark Jones et al.   PLoS One

Biodistribution, pharmacokinetics, and blood compatibility of native and PEGylated tobacco mosaic virus nano-rods and -spheres in mice

(2013) Michael A. Bruckman et al.   VIROLOGY

Chimeric SV40 virus-like particles induce specific cytotoxicity and protective immunity against influenza A virus without the need of adjuvants

(2013) Masaaki Kawano et al.   VIROLOGY

Arranged Sevenfold: Structural Insights into the C-Terminal Oligomerization Domain of Human C4b-Binding Protein

(2012) Thomas Hofmeyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Fusion of the Mycobacterium tuberculosis Antigen 85A to an Oligomerization Domain Enhances Its Immunogenicity in Both Mice and Non-Human Primates

(2012) Alexandra J. Spencer et al.   PLoS One

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The design and interpretation of laboratory assays measuring mosquito transmission of Plasmodium

(2012) Robert E. Sinden et al.   TRENDS IN PARASITOLOGY

Differences in avidity of IgG antibodies to pertussis toxin after acellular pertussis booster vaccination and natural infection

(2012) Alex-Mikael Barkoff et al.   VACCINE

A Plant-Produced Pfs230 Vaccine Candidate Blocks Transmission of Plasmodium falciparum

(2011) Christine E. Farrance et al.   Clinical and Vaccine Immunology

A Viral Vectored Prime-Boost Immunization Regime Targeting the Malaria Pfs25 Antigen Induces Transmission-Blocking Activity

(2011) Anna L. Goodman et al.   PLoS One

A microbial platform for rapid and low-cost virus-like particle and capsomere vaccines

(2011) Anton P.J. Middelberg et al.   VACCINE

The IC50 of anti-Pfs25 antibody in membrane-feeding assay varies among species

(2010) Lediya Cheru et al.   VACCINE

Cutting Edge: Limited Specialization of Dendritic Cell Subsets for MHC Class II-Associated Presentation of Viral Particles

(2009) Susanne A. Keller et al.   JOURNAL OF IMMUNOLOGY

Antibody quantity versus quality after influenza vaccination

(2009) JingQi Feng et al.   VACCINE

The coming of age of virus-like particle vaccines

(2008) Gary T. Jennings et al.   BIOLOGICAL CHEMISTRY

A Vaccine against Nicotine for Smoking Cessation: A Randomized Controlled Trial

(2008) Jacques Cornuz et al.   PLoS One

Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51

(2008) Yimin Wu et al.   PLoS One