Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies

Improvement of Aglycone π-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists

(2019) Wojciech Schönemann et al.   ChemMedChem

Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli

(2019) Kathryn A. Patras et al.   Journal of Innate Immunity

Direct Detection of Tissue-Resident Bacteria and Chronic Inflammation in the Bladder Wall of Postmenopausal Women with Recurrent Urinary Tract Infection

(2019) Nicole J. De Nisco et al.   JOURNAL OF MOLECULAR BIOLOGY

Respiratory Heterogeneity Shapes Biofilm Formation and Host Colonization in Uropathogenic Escherichia coli

(2019) Connor J. Beebout et al.   mBio

Virulence factors of uropathogenic Escherichia coli (UPEC) and correlation with antimicrobial resistance

(2019) Chhaya Shah et al.   BMC MICROBIOLOGY

UTI patients have pre-existing antigen-specific antibody titers against UTI vaccine antigens

(2019) Christina A. Sarkissian et al.   VACCINE

Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence

(2019) Lu Yu et al.   eLife

The Impact of Dietary Transition Metals on Host-Bacterial Interactions

(2018) Christopher A. Lopez et al.   Cell Host & Microbe

Assessing Variability in Hospital-Level Mortality Among U.S. Medicare Beneficiaries With Hospitalizations for Severe Sepsis and Septic Shock

(2018) Kelly M. Hatfield et al.   CRITICAL CARE MEDICINE

Virulence Factor Targeting of the Bacterial Pathogen Staphylococcus aureus for Vaccine and Therapeutics

(2018) Trevor L. Kane et al.   CURRENT DRUG TARGETS

Structural and functional characterization of the Curli adaptor protein CsgF

(2018) Tobias Schubeis et al.   FEBS LETTERS

The iron hand of uropathogenic Escherichia coli: the role of transition metal control in virulence

(2018) Anne E Robinson et al.   Future Microbiology

Evaluation of CpxRA as a Therapeutic Target for Uropathogenic Escherichia coli Infections

(2018) Lana Dbeibo et al.   INFECTION AND IMMUNITY

The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection

(2018) Zhuoran Chen et al.   INTERNATIONAL UROGYNECOLOGY JOURNAL

Evidence of Cross-Regulation in Two Closely Related Pyruvate-Sensing Systems in Uropathogenic Escherichia coli

(2018) Bradley D. Steiner et al.   JOURNAL OF MEMBRANE BIOLOGY

Treatment and Prevention of Recurrent Lower Urinary Tract Infections in Women: A Rapid Review with Practice Recommendations

(2018) Ariana L. Smith et al.   JOURNAL OF UROLOGY

Contribution of yersiniabactin to the virulence of an Escherichia coli sequence type 69 (“clonal group A”) cystitis isolate in murine models of urinary tract infection and sepsis

(2018) James R. Johnson et al.   MICROBIAL PATHOGENESIS

Strategy to reduceE. colibacteraemia based on cohort data from a London teaching hospital

(2018) Desmond Hsu et al.   POSTGRADUATE MEDICAL JOURNAL

Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection

(2018) Vasilios Kalas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation

(2018) Roger D. Klein et al.   mBio

Mitochondrial DNA induces Foley catheter related bladder inflammation via Toll-like receptor 9 activation

(2018) Carlos A. Puyo et al.   Scientific Reports

Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions

(2018) Caitlin N Spaulding et al.   eLife

Characterization of Asymptomatic Bacteriuria Escherichia coli Isolates in Search of Alternative Strains for Efficient Bacterial Interference against Uropathogens

(2018) Christoph Stork et al.   Frontiers in Microbiology

Phosphoethanolamine cellulose enhances curli-mediated adhesion of uropathogenic Escherichia coli to bladder epithelial cells

(2018) Emily C. Hollenbeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of New Genes Involved in Curli Production by a Uropathogenic Escherichia coli Strain from the Highly Virulent O45:K1:H7 Lineage

(2018) Nguyen Thi Khanh Nhu et al.   mBio

Modulating bacterial and gut mucosal interactions with engineered biofilm matrix proteins

(2018) Anna M. Duraj-Thatte et al.   Scientific Reports

Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli

(2018) Natalie S. Omattage et al.   Nature Microbiology

Cross Talk between MarR-Like Transcription Factors Coordinates the Regulation of Motility in Uropathogenic Escherichia coli

(2018) Courtney L. Luterbach et al.   INFECTION AND IMMUNITY

Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through Iterative Rational Drug Design

(2018) Amarendar Reddy Maddirala et al.   JOURNAL OF MEDICINAL CHEMISTRY

Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets

(2018) Maximilian M. Sauer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD

(2018) Minge Du et al.   NATURE

Benefits and Harms of Treatment of Asymptomatic Bacteriuria: A Systematic Review and Meta-analysis by the European Association of Urology Urological Infection Guidelines Panel

(2017) Bela Köves et al.   EUROPEAN UROLOGY

Whole-genome comparison of urinary pathogenic Escherichia coli and faecal isolates of UTI patients and healthy controls

(2017) Karen Leth Nielsen et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Biofilm Formation by Uropathogenic Escherichia coli Is Favored under Oxygen Conditions That Mimic the Bladder Environment

(2017) Allison Eberly et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Histidine Residue of QseC Is Required for Canonical Signaling between QseB and PmrB in Uropathogenic Escherichia coli

(2017) Erin J. Breland et al.   JOURNAL OF BACTERIOLOGY

Enterobacteria secrete an inhibitor of Pseudomonas virulence during clinical bacteriuria

(2017) Shannon I. Ohlemacher et al.   JOURNAL OF CLINICAL INVESTIGATION

Comprehensive expression analysis of pathogenicity genes in uropathogenic Escherichia coli strains

(2017) Gloria Luz Paniagua-Contreras et al.   MICROBIAL PATHOGENESIS

Sites for Dynamic Protein-Carbohydrate Interactions of O- and C-Linked Mannosides on the E. coli FimH Adhesin

(2017) Mohamed Touaibia et al.   MOLECULES

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

(2017) Caitlin N. Spaulding et al.   NATURE

Copper import in Escherichia coli by the yersiniabactin metallophore system

(2017) Eun-Ik Koh et al.   Nature Chemical Biology

Nucleation and growth of a bacterial functional amyloid at single-fiber resolution

(2017) Mike Sleutel et al.   Nature Chemical Biology

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis

(2017) Christopher W. Seymour et al.   NEW ENGLAND JOURNAL OF MEDICINE

Catheterization alters bladder ecology to potentiateStaphylococcus aureusinfection of the urinary tract

(2017) Jennifer N. Walker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling by two-component system noncognate partners promotes intrinsic tolerance to polymyxin B in uropathogenicEscherichia coli

(2017) Kirsten R. Guckes et al.   Science Signaling

Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections

(2017) Henry L. Schreiber et al.   Science Translational Medicine

The Cryoelectron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod

(2017) Manuela K. Hospenthal et al.   STRUCTURE

Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial

(2017) Andreas Kronenberg et al.   BMJ-British Medical Journal

Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease

(2017) Nicole M. Gilbert et al.   PLoS Pathogens

Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial

(2017) Andreas Kronenberg et al.   BMJ-British Medical Journal

Metabolic Adaptations of Uropathogenic E. coli in the Urinary Tract

(2017) Riti Mann et al.   Frontiers in Cellular and Infection Microbiology

Signaling by two-component system noncognate partners promotes intrinsic tolerance to polymyxin B in uropathogenicEscherichia coli

(2017) Kirsten R. Guckes et al.   Science Signaling

Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions

(2017) Vasilios Kalas et al.   Science Advances

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection

(2017) Wei Xu et al.   npj Biofilms and Microbiomes

The Increase in Hospitalizations for Urinary Tract Infections and the Associated Costs in the United States, 1998–2011

(2017) Jacob E. Simmering et al.   Open Forum Infectious Diseases

Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection

(2016) Matt S. Conover et al.   Cell Host & Microbe

Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI

(2016) Cassie Jarvis et al.   ChemMedChem

The Pathogenic Potential of Proteus mirabilis Is Enhanced by Other Uropathogens during Polymicrobial Urinary Tract Infection

(2016) Chelsie E. Armbruster et al.   INFECTION AND IMMUNITY

Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011–2014

(2016) Lindsey M. Weiner et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Resistance and virulence potential of uropathogenic Escherichia coli strains isolated from patients hospitalized in urology departments: a French prospective multicentre study

(2016) Jean-Philippe Lavigne et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections

(2016) Laurel Mydock-McGrane et al.   JOURNAL OF MEDICINAL CHEMISTRY

How Often Do Clinically Diagnosed Catheter-Associated Urinary Tract Infections in Nursing Homes Meet Standardized Criteria?

(2016) Chelsie E. Armbruster et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Fibrinogen Release and Deposition on Urinary Catheters Placed during Urological Procedures

(2016) Ana L. Flores-Mireles et al.   JOURNAL OF UROLOGY

Enterococcus faecalis Ebp pili are important for cell-cell aggregation and intraspecies gene transfer

(2016) Sabina Leanti La Rosa et al.   MICROBIOLOGY-SGM

Proteus mirabilisfimbriae- and urease-dependent clusters assemble in an extracellular niche to initiate bladder stone formation

(2016) Jessica N. Schaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody-Based Therapy for Enterococcal Catheter-Associated Urinary Tract Infections

(2016) Ana L. Flores-Mireles et al.   mBio

Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens

(2016) Sirijan Santajit et al.   Biomed Research International

A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease

(2016) Valerie P. O'Brien et al.   Nature Microbiology

Blocking Yersiniabactin Import Attenuates Extraintestinal Pathogenic Escherichia coli in Cystitis and Pyelonephritis and Represents a Novel Target To Prevent Urinary Tract Infection

(2015) Ariel R. Brumbaugh et al.   INFECTION AND IMMUNITY

Rapid and Profound Shifts in the Vaginal Microbiota Following Antibiotic Treatment for Bacterial Vaginosis

(2015) Bryan T. Mayer et al.   JOURNAL OF INFECTIOUS DISEASES

The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation

(2015) Margery L. Evans et al.   MOLECULAR CELL

Strain- and host species-specific inflammasome activation, IL-1β release and cell death in macrophages infected with uropathogenic Escherichia coli

(2015) K Schaale et al.   Mucosal Immunology

Urinary tract infections: epidemiology, mechanisms of infection and treatment options

(2015) Ana L. Flores-Mireles et al.   NATURE REVIEWS MICROBIOLOGY

Dysregulation ofEscherichia coliα-hemolysin expression alters the course of acute and persistent urinary tract infection

(2015) Kanna Nagamatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Amyloid Formation: Structural Insights into Curli Biogensis

(2015) Nani Van Gerven et al.   TRENDS IN MICROBIOLOGY

Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial

(2015) Ildikó Gágyor et al.   BMJ-British Medical Journal

Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection

(2015) Ann E. Lin et al.   PLoS Pathogens

Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial

(2015) Ildikó Gágyor et al.   BMJ-British Medical Journal

Network Analysis Reveals Sex- and Antibiotic Resistance-Associated Antivirulence Targets in Clinical Uropathogens

(2015) Kaveri S. Parker et al.   ACS Infectious Diseases

Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium

(2014) Marzena Schiwon et al.   CELL

Intracellular Bacteria in the Pathogenesis of Escherichia coli Urinary Tract Infection in Children

(2014) Luciana Robino et al.   CLINICAL INFECTIOUS DISEASES

Drug resistance and virulence of uropathogenic Escherichia coli from Shanghai, China

(2014) Yanchun Wang et al.   JOURNAL OF ANTIBIOTICS

Identification of a Novel Nutrient-Sensing Histidine Kinase/Response Regulator Network in Escherichia coli

(2014) S. Behr et al.   JOURNAL OF BACTERIOLOGY

In silico and in vivo studies of truncated forms of flagellin (FliC) of enteroaggregative Escherichia coli fused to FimH from uropathogenic Escherichia coli as a vaccine candidate against urinary tract infections

(2014) Nastaran Sadat Savar et al.   JOURNAL OF BIOTECHNOLOGY

Structure and function of enterotoxigenicEscherichia colifimbriae from differing assembly pathways

(2014) Narges Mortezaei et al.   MOLECULAR MICROBIOLOGY

Multistate Point-Prevalence Survey of Health Care–Associated Infections

(2014) Shelley S. Magill et al.   NEW ENGLAND JOURNAL OF MEDICINE

F9 Fimbriae of Uropathogenic Escherichia coli Are Expressed at Low Temperature and Recognise Galβ1-3GlcNAc-Containing Glycans

(2014) Daniël J. Wurpel et al.   PLoS One

Dynamic Interaction between the CpxA Sensor Kinase and the Periplasmic Accessory Protein CpxP Mediates Signal Recognition in E. coli

(2014) Karolin Tschauner et al.   PLoS One

Host-specific induction ofEscherichia colifitness genes during human urinary tract infection

(2014) Sargurunathan Subashchandrabose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EbpA vaccine antibodies block binding of Enterococcus faecalis to fibrinogen to prevent catheter-associated bladder infection in mice

(2014) A. L. Flores-Mireles et al.   Science Translational Medicine

Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis

(2014) Thomas J. Hannan et al.   EBioMedicine

Trends in catheter-associated urinary tract infections among a national cohort of hospitalized adults, 2001-2010

(2013) Kelly R. Daniels et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Urinary Tract Infection Syndromes

(2013) Betsy Foxman   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Antibiotic prescribing for adults in ambulatory care in the USA, 2007–09

(2013) Daniel J. Shapiro et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Rare Emergence of Symptoms during Long-Term Asymptomatic Escherichia coli 83972 Carriage without an Altered Virulence Factor Repertoire

(2013) Béla Köves et al.   JOURNAL OF UROLOGY

Solid-state NMR for bacterial biofilms

(2013) Courtney Reichhardt et al.   MOLECULAR PHYSICS

Chaperone-Usher Fimbriae of Escherichia coli

(2013) Daniël J. Wurpel et al.   PLoS One

Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor

(2013) K. R. Guckes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation

(2013) D. J. Schwartz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical significance of Staphylococcus aureus bacteriuria at a tertiary care hospital

(2013) Mayar Al Mohajer et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Genomic Diversity and Fitness of E. coli Strains Recovered from the Intestinal and Urinary Tracts of Women with Recurrent Urinary Tract Infection

(2013) S. L. Chen et al.   Science Translational Medicine

Streptomycin-Induced Inflammation Enhances Escherichia coli Gut Colonization Through Nitrate Respiration

(2013) A. M. Spees et al.   mBio

The Staphylococcus aureus ArlRS Two-Component System Is a Novel Regulator of Agglutination and Pathogenesis

(2013) Jennifer N. Walker et al.   PLoS Pathogens

Detection of intracellular bacterial communities in a child withEscherichia colirecurrent urinary tract infections

(2013) Luciana Robino et al.   Pathogens and Disease

Enterococcus faecalis Overcomes Foreign Body-Mediated Inflammation To Establish Urinary Tract Infections

(2012) Pascale S. Guiton et al.   INFECTION AND IMMUNITY

Cefpodoxime vs Ciprofloxacin for Short-Course Treatment of Acute Uncomplicated Cystitis

(2012) Thomas M. Hooton et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The siderophore yersiniabactin binds copper to protect pathogens during infection

(2012) Kaveri S Chaturvedi et al.   Nature Chemical Biology

Uncomplicated Urinary Tract Infection

(2012) Thomas M. Hooton   NEW ENGLAND JOURNAL OF MEDICINE

Randomized, Placebo-Controlled Phase 2 Trial of a Lactobacillus crispatus Probiotic Given Intravaginally for Prevention of Recurrent Urinary Tract Infection

(2011) Ann E. Stapleton et al.   CLINICAL INFECTIOUS DISEASES

Population Dynamics and Niche Distribution of Uropathogenic Escherichia coli during Acute and Chronic Urinary Tract Infection

(2011) Drew J. Schwartz et al.   INFECTION AND IMMUNITY

Innate Transcriptional Networks Activated in Bladder in Response to Uropathogenic Escherichia coli Drive Diverse Biological Pathways and Rapid Synthesis of IL-10 for Defense against Bacterial Urinary Tract Infection

(2011) B. L. Duell et al.   JOURNAL OF IMMUNOLOGY

B Cell Infiltration and Lymphonodular Hyperplasia in Bladder Submucosa of Patients With Persistent Bacteriuria and Recurrent Urinary Tract Infections

(2011) T.A. Schlager et al.   JOURNAL OF UROLOGY

Treatment and Prevention of Urinary Tract Infection with Orally Active FimH Inhibitors

(2011) C. K. Cusumano et al.   Science Translational Medicine

Multicenter Randomized Controlled Trial of Bacterial Interference for Prevention of Urinary Tract Infection in Patients With Neurogenic Bladder

(2011) Rabih O. Darouiche et al.   UROLOGY

Characteristics ofEscherichia colicausing persistence or relapse of urinary tract infections: Phylogenetic groups, virulence factors and biofilm formation

(2011) Karen Ejrnæs et al.   Virulence

The Bacterial Fimbrial Tip Acts as a Mechanical Force Sensor

(2011) Pavel Aprikian et al.   PLOS BIOLOGY

Preventing Staphylococcus aureus Sepsis through the Inhibition of Its Agglutination in Blood

(2011) Molly McAdow et al.   PLoS Pathogens

Symptomatic treatment (ibuprofen) or antibiotics (ciprofloxacin) for uncomplicated urinary tract infection? - Results of a randomized controlled pilot trial

(2010) Jutta Bleidorn et al.   BMC Medicine

Systematic Review and Meta‐Analysis: Reminder Systems to Reduce Catheter‐Associated Urinary Tract Infections and Urinary Catheter Use in Hospitalized Patients

(2010) Jennifer Meddings et al.   CLINICAL INFECTIOUS DISEASES

The Innate Immune Response to Uropathogenic Escherichia coli Involves IL-17A in a Murine Model of Urinary Tract Infection

(2010) Kelsey E. Sivick et al.   JOURNAL OF IMMUNOLOGY

FimH Antagonists for the Oral Treatment of Urinary Tract Infections: From Design and Synthesis to in Vitro and in Vivo Evaluation

(2010) Tobias Klein et al.   JOURNAL OF MEDICINAL CHEMISTRY

Escherichia coli 83972 Bacteriuria Protects Against Recurrent Lower Urinary Tract Infections in Patients With Incomplete Bladder Emptying

(2010) Fredrik Sundén et al.   JOURNAL OF UROLOGY

The epidemiology of urinary tract infection

(2010) Betsy Foxman   Nature Reviews Urology

Early Severe Inflammatory Responses to Uropathogenic E. coli Predispose to Chronic and Recurrent Urinary Tract Infection

(2010) Thomas J. Hannan et al.   PLoS Pathogens

Escherichia coli Global Gene Expression in Urine from Women with Urinary Tract Infection

(2010) Erin C. Hagan et al.   PLoS Pathogens

Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues

(2009) Alice G. Cheng et al.   FASEB JOURNAL

Crystalline bacterial biofilm formation on urinary catheters by urease-producing urinary tract pathogens: a simple method of control

(2009) R. J. Broomfield et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Increasing Prevalence and Associated Risk Factors for Methicillin Resistant Staphylococcus Aureus Bacteriuria

(2009) Jonathan C. Routh et al.   JOURNAL OF UROLOGY

QseC-mediated dephosphorylation of QseB is required for expression of genes associated with virulence in uropathogenicEscherichia coli

(2009) Maria Kostakioti et al.   MOLECULAR MICROBIOLOGY

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

(2009) Lynette Cegelski et al.   Nature Chemical Biology

TLR4-mediated expulsion of bacteria from infected bladder epithelial cells

(2009) J. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding

(2009) Swaine L. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths

(2009) Marie Touchon et al.   PLoS Genetics

Quantitative Metabolomics Reveals an Epigenetic Blueprint for Iron Acquisition in Uropathogenic Escherichia coli

(2009) Jeffrey P. Henderson et al.   PLoS Pathogens

G-CSF induction early in uropathogenicEscherichia coliinfection of the urinary tract modulates host immunity

(2008) Molly A. Ingersoll et al.   CELLULAR MICROBIOLOGY

Complicated Catheter-Associated Urinary Tract Infections Due to Escherichia coli and Proteus mirabilis

(2008) S. M. Jacobsen et al.   CLINICAL MICROBIOLOGY REVIEWS

Current concepts of molecular defence mechanisms operative during urinary tract infection

(2008) T. Weichhart et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Federal Funding for the Study of Antimicrobial Resistance in Nosocomial Pathogens: No ESKAPE

(2008) Louis B. Rice   JOURNAL OF INFECTIOUS DISEASES