A controlled human Schistosoma mansoni infection model to advance novel drugs, vaccines and diagnostics

Katayama Syndrome Without Schistosoma mansoni Eggs

(2019) Marijke C.C. Langenberg et al.   ANNALS OF INTERNAL MEDICINE

DIABLO: an integrative approach for identifying key molecular drivers from multi-omic assays

(2019) Amrit Singh et al.   BIOINFORMATICS

Performance of an Ultra-Sensitive Assay Targeting the Circulating Anodic Antigen (CAA) for Detection of Schistosoma mansoni Infection in a Low Endemic Area in Brazil

(2019) Mariana Silva Sousa et al.   Frontiers in Immunology

Sm-p80-based vaccine trial in baboons: efficacy when mimicking natural conditions of chronic disease, praziquantel therapy, immunization, and Schistosoma mansoni re-encounter

(2018) Arif J. Siddiqui et al.   Annals of the New York Academy of Sciences

Improved diagnosis of active Schistosoma infection in travellers and migrants using the ultra-sensitive in-house lateral flow test for detection of circulating anodic antigen (CAA) in serum

(2018) Rebecca van Grootveld et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Establishing the Production of Male Schistosoma mansoni Cercariae for a Controlled Human Infection Model

(2018) Jacqueline J Janse et al.   JOURNAL OF INFECTIOUS DISEASES

Experimental infection of human volunteers

(2018) Meta Roestenberg et al.   LANCET INFECTIOUS DISEASES

Host Defense Versus Immunosuppression: Unisexual Infection With Male or Female Schistosoma mansoni Differentially Impacts the Immune Response Against Invading Cercariae

(2018) Martina Sombetzki et al.   Frontiers in Immunology

Sm-p80-based schistosomiasis vaccine: double-blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission-blocking efficacy

(2018) Weidong Zhang et al.   Annals of the New York Academy of Sciences

Prevalence of Atopy following Mass Drug Administration with Albendazole: A Study in School Children on Flores Island, Indonesia

(2018) Steven L. Staal et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Early Induction of Human Regulatory Dermal Antigen Presenting Cells by Skin-Penetrating Schistosoma Mansoni Cercariae

(2018) Béatrice M. F. Winkel et al.   Frontiers in Immunology

lmerTest Package: Tests in Linear Mixed Effects Models

(2017) Alexandra Kuznetsova et al.   Journal of Statistical Software

Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial

(2017) Celina Jin et al.   LANCET

mixOmics: An R package for ‘omics feature selection and multiple data integration

(2017) Florian Rohart et al.   PLoS Computational Biology

Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?

(2017) Robert Bergquist et al.   Infectious Diseases of Poverty

Single-dose Live Oral Cholera Vaccine CVD 103-HgR Protects Against Human Experimental Infection WithVibrio choleraeO1 El Tor

(2016) Wilbur H. Chen et al.   CLINICAL INFECTIOUS DISEASES

Randomized controlled trials for influenza drugs and vaccines: a review of controlled human infection studies

(2016) Shobana Balasingam et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Diagnosis and treatment based on quantitative PCR after controlled human malaria infection

(2016) Jona Walk et al.   MALARIA JOURNAL

Conditioning of naive CD4+ T cells for enhanced peripheral Foxp3 induction by nonspecific bystander inflammation

(2016) Lucas J Thompson et al.   NATURE IMMUNOLOGY

Workshop report: Schistosomiasis vaccine clinical development and product characteristics

(2016) Annie X. Mo et al.   VACCINE

Schistosomiasis vaccine candidate Sm14/GLA-SE: Phase 1 safety and immunogenicity clinical trial in healthy, male adults

(2016) Marilia Santini-Oliveira et al.   VACCINE

Advancing a vaccine to prevent human schistosomiasis

(2016) Maureen Merrifield et al.   VACCINE

Fitting Linear Mixed-Effects Models Usinglme4

(2015) Douglas Bates et al.   Journal of Statistical Software

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Theo Vos et al.   LANCET

Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes

(2015) Paul LAM Corstjens et al.   Parasites & Vectors

Human schistosomiasis

(2014) Daniel G Colley et al.   LANCET

Tools for diagnosis, monitoring and screening of Schistosoma infections utilizing lateral-flow based assays and upconverting phosphor labels

(2014) PAUL L. A. M. CORSTJENS et al.   PARASITOLOGY

A Five-Country Evaluation of a Point-of-Care Circulating Cathodic Antigen Urine Assay for the Prevalence of Schistosoma mansoni

(2013) Daniel G. Colley et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

World Medical Association Declaration of Helsinki

(2013)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Comparative efficacy of one versus two doses of praziquantel on cure rate of Schistosoma mansoni infection and re-infection in Mayuge District, Uganda

(2013) Edridah M. Tukahebwa et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Schistosomiasis: Current Epidemiology and Management in Travelers

(2013) Eyal Meltzer et al.   Current Infectious Disease Reports

The Immune Response to Schistosome Antigens in Formerly Infected Travelers

(2011) Darius Soonawala et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Utility of Repeated Praziquantel Dosing in the Treatment of Schistosomiasis in High-Risk Communities in Africa: A Systematic Review

(2011) Charles H. King et al.   PLoS Neglected Tropical Diseases

Human schistosomiasis mansoni: Immune responses during acute and chronic phases of the infection

(2008) Iramaya Rodrigues Caldas et al.   ACTA TROPICA

Application of a circulating-cathodic-antigen (CCA) strip test and real-time PCR, in comparison with microscopy, for the detection ofSchistosoma haematobiumin urine samples from Ghana

(2008) B.B. Obeng et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY