Structural equilibrium underlying ligand-dependent activation of β2-adrenoreceptor

Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations

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Structural Basis for G Protein–Coupled Receptor Signaling

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Allosteric Coupling of Drug Binding and Intracellular Signaling in the A 2A Adenosine Receptor

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5-HT 2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

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GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures

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Selectivity determinants of GPCR–G-protein binding

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Single-molecule analysis of ligand efficacy in β2AR–G-protein activation

(2017) G. Glenn Gregorio et al.   NATURE

Xplor-NIH for molecular structure determination from NMR and other data sources

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Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor

(2017) Andras S. Solt et al.   Nature Communications

Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR

(2017) Yuichi Minato et al.   Scientific Reports

Dynamic equilibrium on DNA defines transcriptional regulation of a multidrug binding transcriptional repressor, LmrR

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Successful Strategies to Determine High-Resolution Structures of GPCRs

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Two-Dimensional NMR Lineshape Analysis

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Structural Insights into the Dynamic Process of β 2 -Adrenergic Receptor Signaling

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Visualizing transient dark states by NMR spectroscopy

(2015) Nicholas J. Anthis et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Stabilization of G protein-coupled receptors by point mutations

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Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution inEscherichia coli

(2014) Pascal Egloff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nmrglue: an open source Python package for the analysis of multidimensional NMR data

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The structure of the box C/D enzyme reveals regulation of RNA methylation

(2013) Audrone Lapinaite et al.   NATURE

Activation and allosteric modulation of a muscarinic acetylcholine receptor

(2013) Andrew C. Kruse et al.   NATURE

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody

(2013) Aaron M. Ring et al.   NATURE

Structural Features for Functional Selectivity at Serotonin Receptors

(2013) D. Wacker et al.   SCIENCE

Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies

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TheArabidopsisB3 Domain Protein VERNALIZATION1 (VRN1) Is Involved in Processes Essential for Development, with Structural and Mutational Studies Revealing Its DNA-binding Surface

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Structure of the agonist-bound neurotensin receptor

(2012) Jim F. White et al.   NATURE

N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor

(2012) Yaozhong Zou et al.   PLoS One

Biased Signaling Pathways in  2-Adrenergic Receptor Characterized by 19F-NMR

(2012) J. J. Liu et al.   SCIENCE

Requirements on Paramagnetic Relaxation Enhancement Data for Membrane Protein Structure Determination by NMR

(2012) Daniel Gottstein et al.   STRUCTURE

Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region

(2012) Yutaka Kofuku et al.   Nature Communications

A simple protocol for amino acid type selective isotope labeling in insect cells with improved yields and high reproducibility

(2011) Alvar D. Gossert et al.   JOURNAL OF BIOMOLECULAR NMR

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

(2011) Guillaume Lebon et al.   NATURE

The structural basis for agonist and partial agonist action on a β1-adrenergic receptor

(2011) Tony Warne et al.   NATURE

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Bayesian spectral deconvolution with the exchange Monte Carlo method

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NMR Solution Structure and DNA-binding Model of the DNA-binding Domain of Competence Protein A

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Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer

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The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Stabilization of the Human β2-Adrenergic Receptor TM4–TM3–TM5 Helix Interface by Mutagenesis of Glu1223.41, A Critical Residue in GPCR Structure

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