Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations

Published 2019 View Full Article

Title

Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations

Authors

Keywords

G protein-coupled receptor, GPCR, angiotensin II type 1 receptor, angiotensin receptor blocker, ARB, biased agonism, functional selectivity, double electron-electron resonance spectroscopy, DEER, molecular dynamics simulations, conformational selection, beta-arrestin, heterotrimeric G protein

Journal

CELL

Volume -, Issue -, Pages -

Publisher

Elsevier BV

Online

2019-01-11

DOI

10.1016/j.cell.2018.12.005

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