Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio

Effect of PKCα expression on Bcl-2 phosphorylation and cell death by hypericin

(2014) Jaroslava Joniova et al.   APOPTOSIS

Hypericins: biotechnological production from cell and organ cultures

(2014) Hosakatte Niranjana Murthy et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Old, new and emerging functions of caspases

(2014) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

Ionic mechanisms in pancreatic β cell signaling

(2014) Shao-Nian Yang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

St John's Wort (Hypericum perforatum L.) Photomedicine: Hypericin-Photodynamic Therapy Induces Metastatic Melanoma Cell Death

(2014) Britta Kleemann et al.   PLoS One

Apolipoprotein CIII hyperactivates β cell CaV1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src

(2013) Yue Shi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Diagnosis and management of insulinoma

(2013) Takehiro Okabayashi   WORLD JOURNAL OF GASTROENTEROLOGY

Molecular Response to Hypericin-Induced Photodamage

(2012) B. Krammer et al.   CURRENT MEDICINAL CHEMISTRY

Cell death response of U87 glioma cells on hypericin photoactivation is mediated by dynamics of hypericin subcellular distribution and its aggregation in cellular organelles

(2012) Veronika Huntosova et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

St. John's Wort inhibits insulin signaling in murine and human adipocytes

(2011) Allison J. Richard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

New therapeutic options for metastatic malignant insulinomas

(2011) Wouter W. de Herder et al.   CLINICAL ENDOCRINOLOGY

Hypericin, the active component of St. John's wort, inhibits glutamate release in the rat cerebrocortical synaptosomes via a mitogen-activated protein kinase-dependent pathway

(2010) Yi Chang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hypericins as Potential Leads for New Therapeutics

(2010) Anastasia Karioti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Multifaceted Photocytotoxic Profile of Hypericin

(2009) Theodossis A. Theodossiou et al.   MOLECULAR PHARMACEUTICS