St John's Wort (Hypericum perforatum L.) Photomedicine: Hypericin-Photodynamic Therapy Induces Metastatic Melanoma Cell Death

Determination of apoptotic and necrotic cell death in vitro and in vivo

(2013) Tom Vanden Berghe et al.   METHODS

Nitrosylhemoglobin in photodynamically stressed human tumors growing in nude mice

(2013) Monika Jakubowska et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Teaching the basics of redox biology to medical and graduate students: Oxidants, antioxidants and disease mechanisms

(2013) Balaraman Kalyanaraman   Redox Biology

Comparison of Stain-Free gels with traditional immunoblot loading control methodology

(2012) Alex D. Colella et al.   ANALYTICAL BIOCHEMISTRY

Daylight-mediated photodynamic therapy of moderate to thick actinic keratoses of the face and scalp: a randomized multicentre study

(2012) S.R. Wiegell et al.   BRITISH JOURNAL OF DERMATOLOGY

Phosphatidylserine exposure during apoptosis reflects bidirectional trafficking between plasma membrane and cytoplasm

(2012) S-H Lee et al.   CELL DEATH AND DIFFERENTIATION

Molecular Response to Hypericin-Induced Photodamage

(2012) B. Krammer et al.   CURRENT MEDICINAL CHEMISTRY

Associations between environmental factors and incidence of cutaneous melanoma. Review

(2012) Katarina Volkovova et al.   Environmental Health

Generation and clonal isolation of retinal stem cells from human embryonic stem cells

(2012) Laura Clarke et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Melanoma: New Insights and New Therapies

(2012) Vasiliki A. Nikolaou et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A brief history of melanoma

(2012) Vito W. Rebecca et al.   MELANOMA RESEARCH

Cell death response of U87 glioma cells on hypericin photoactivation is mediated by dynamics of hypericin subcellular distribution and its aggregation in cellular organelles

(2012) Veronika Huntosova et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation

(2012) M Baritaud et al.   Cell Death & Disease

The adult retinal stem cell is a rare cell in the ciliary epithelium whose progeny can differentiate into photoreceptors

(2012) B. G. Ballios et al.   Biology Open

A randomized, multicentre study of directed daylight exposure times of 1½ vs. 2½ h in daylight-mediated photodynamic therapy with methyl aminolaevulinate in patients with multiple thin actinic keratoses of the face and scalp

(2011) S.R. Wiegell et al.   BRITISH JOURNAL OF DERMATOLOGY

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Photodynamic therapy-induced killing is enhanced in depigmented metastatic melanoma cells

(2011) Krishna V. Sharma et al.   CELL BIOLOGY INTERNATIONAL

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

(2011) Ganta Chaitanya et al.   Cell Communication and Signaling

Enhanced Antiproliferative and Apoptotic Response of HT-29 Adenocarcinoma Cells to Combination of Photoactivated Hypericin and Farnesyltransferase Inhibitor Manumycin A

(2011) Veronika Sačková et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Daylight photodynamic therapy for actinic keratosis: an international consensus

(2011) S.R. Wiegell et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Depigmentation in melanomas increases the efficacy of hypericin-mediated photodynamic-induced cell death

(2011) Krishna V. Sharma et al.   Photodiagnosis and Photodynamic Therapy

Degradation of HIF-1alpha under Hypoxia Combined with Induction of Hsp90 Polyubiquitination in Cancer Cells by Hypericin: a Unique Cancer Therapy

(2011) Tilda Barliya et al.   PLoS One

ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy

(2010) Michael Dewaele et al.   Autophagy

Histone H2AX: The missing link in AIF-mediated caspase-independent programmed necrosis

(2010) Mathieu Baritaud et al.   CELL CYCLE

Hypericins as Potential Leads for New Therapeutics

(2010) Anastasia Karioti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage

(2010) Michael Dewaele et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cellular and Molecular Mechanisms of Photodynamic Hypericin Therapy for Nasopharyngeal Carcinoma Cells

(2010) X. Wang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Comparative in vitro study on the characteristics of different photosensitizers employed in PDT

(2010) Juergen Berlanda et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Poly(ADP-ribose) polymerase-1 (PARP-1) and its therapeutic implications

(2010) Rupinder K. Sodhi et al.   VASCULAR PHARMACOLOGY

Melanomas display increased cytoprotection to hypericin-mediated cytotoxicity through the induction of autophagy

(2009) Lester M. Davids et al.   CELL BIOLOGY INTERNATIONAL

Why do melanomas get so dark?

(2009) Rossitza Lazova et al.   EXPERIMENTAL DERMATOLOGY

Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos

(2009) Yingfei Wang et al.   EXPERIMENTAL NEUROLOGY

Autophagy in cutaneous malignant melanoma

(2009) Rossitza Lazova et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Influence of Melanosome Dynamics on Melanoma Drug Sensitivity

(2009) Kevin G. Chen et al.   JNCI-Journal of the National Cancer Institute

The Multifaceted Photocytotoxic Profile of Hypericin

(2009) Theodossis A. Theodossiou et al.   MOLECULAR PHARMACEUTICS

The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells

(2009) Jaromír Mikeš et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells

(2009) Rastislav Jendželovský et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Hypericin Hydroquinone: Potential as a Red-Far Red Photosensitizer?

(2009) Theodossis A. Theodossiou et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma

(2009) Kevin G. Chen et al.   Pigment Cell & Melanoma Research

Integrative Analysis of Epigenetic Modulation in Melanoma Cell Response to Decitabine: Clinical Implications

(2009) Ruth Halaban et al.   PLoS One

Regulation of melanogenesis - controversies and new concepts

(2008) Karin U. Schallreuter et al.   EXPERIMENTAL DERMATOLOGY

Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy

(2008) Anna A. Brożyna et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cells

(2008) Andrzej Slominski et al.   INTERNATIONAL JOURNAL OF CANCER

The use of total protein stains as loading controls: An alternative to high-abundance single-protein controls in semi-quantitative immunoblotting

(2008) Georgina M. Aldridge et al.   JOURNAL OF NEUROSCIENCE METHODS

Mechanisms involved in the cell cycle and apoptosis of HT-29 cells pre-treated with MK-886 prior to photodynamic therapy with hypericin

(2008) Ján Kleban et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Hypericin phototoxicity induces different modes of cell death in melanoma and human skin cells

(2008) Lester M. Davids et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Apoptosis and necrosis: Detection, discrimination and phagocytosis

(2008) Dmitri V. Krysko et al.   METHODS

Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma

(2008) Peter Hersey et al.   Pigment Cell & Melanoma Research