lncRNA-PLACT1 sustains activation of NF-κB pathway through a positive feedback loop with IκBα/E2F1 axis in pancreatic cancer

Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression

(2019) Yunzhao Chen et al.   Molecular Cancer

LncRNA-FEZF1-AS1 promotes tumor proliferation and metastasis in colorectal cancer by regulating PKM2 signaling

(2018) Zehua Bian et al.   CLINICAL CANCER RESEARCH

Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis

(2018) Junpei Wang et al.   DIABETES

Noncoding RNAs: Master Regulators of Inflammatory Signaling

(2018) Chen Li Chew et al.   TRENDS IN MOLECULAR MEDICINE

The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1

(2018) Feng Su et al.   Cell Death & Disease

RGG-box in hnRNPA1 specifically recognizes the telomere G-quadruplex DNA and enhances the G-quadruplex unfolding ability of UP1 domain

(2018) Meenakshi Ghosh et al.   NUCLEIC ACIDS RESEARCH

LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment

(2018) Changhao Chen et al.   Nature Communications

Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update

(2017) Alok A. Khorana et al.   JOURNAL OF CLINICAL ONCOLOGY

Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR-223/NLRP3 axis

(2017) Yong Zhang et al.   JOURNAL OF PINEAL RESEARCH

A Constitutive Intrinsic Inflammatory Signaling Circuit Composed of miR-196b, Meis2, PPP3CC, and p65 Drives Prostate Cancer Castration Resistance

(2017) Ji-Hak Jeong et al.   MOLECULAR CELL

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

(2017) Yvonne Y Li et al.   Nature Communications

Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2

(2016) Ja Hyun Koo et al.   GASTROENTEROLOGY

Metastatic Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline

(2016) Davendra P.S. Sohal et al.   JOURNAL OF CLINICAL ONCOLOGY

Pancreatic cancer

(2016) Terumi Kamisawa et al.   LANCET

miR-148a-3p represses proliferation and EMT by establishing regulatory circuits between ERBB3/AKT2/c-myc and DNMT1 in bladder cancer

(2016) Xiao Wang et al.   Cell Death & Disease

A Cytoplasmic NF-κB Interacting Long Noncoding RNA Blocks IκB Phosphorylation and Suppresses Breast Cancer Metastasis

(2015) Bodu Liu et al.   CANCER CELL

Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

American Gastroenterological Association Institute Guideline on the Diagnosis and Management of Asymptomatic Neoplastic Pancreatic Cysts

(2015) Santhi Swaroop Vege et al.   GASTROENTEROLOGY

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer

(2015) Jens U. Marquardt et al.   JOURNAL OF HEPATOLOGY

The emerging role of lncRNAs in cancer

(2015) Maite Huarte   NATURE MEDICINE

The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation

(2014) P. Wang et al.   SCIENCE

A positive feedback loop between EBP2 and c-Myc regulates rDNA transcription, cell proliferation and tumorigenesis

(2014) P Liao et al.   Cell Death & Disease

p50-associated COX-2 extragenic RNA (PACER) activates COX-2 gene expression by occluding repressive NF-κB complexes

(2014) Michal Krawczyk et al.   eLife

The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

(2013) Phillip Grote et al.   DEVELOPMENTAL CELL

Long Noncoding RNA in Prostate, Bladder, and Kidney Cancer

(2013) Elena S. Martens-Uzunova et al.   EUROPEAN UROLOGY

PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-κB

(2013) Jiajie Hou et al.   JOURNAL OF HEPATOLOGY

A three-state model for the regulation of telomerase by TERRA and hnRNPA1

(2013) Sophie Redon et al.   NUCLEIC ACIDS RESEARCH

The long non-coding RNAFendrrlinks epigenetic control mechanisms to gene regulatory networks in mammalian embryogenesis

(2013) Phillip Grote et al.   RNA Biology

GSK-3α Promotes Oncogenic KRAS Function in Pancreatic Cancer via TAK1–TAB Stabilization and Regulation of Noncanonical NF-κB

(2013) Deepali Bang et al.   Cancer Discovery

A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics

(2013) Nicole A Rapicavoli et al.   eLife

KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

(2012) Jianhua Ling et al.   CANCER CELL

TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets

(2012) Libing Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Nuclear Export of the NF-κB Inhibitor IκBα Is Required for Proper B Cell and Secondary Lymphoid Tissue Formation

(2011) Shelly M. Wuerzberger-Davis et al.   IMMUNITY

NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells

(2011) S. Galardi et al.   NUCLEIC ACIDS RESEARCH

Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-κB signaling and depleting Bcr-Abl

(2010) Zhongzheng Lu et al.   Molecular Cancer

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Promyelocytic leukemia protein induces apoptosis due to caspase-8 activation via the repression of NFκB activation in glioblastoma

(2008) Kazuyuki Kuwayama et al.   NEURO-ONCOLOGY