LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment

Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

(2017) Yu Zhu et al.   IMMUNITY

The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance

(2017) Jana Seiler et al.   NUCLEIC ACIDS RESEARCH

Explaining negative kin discrimination in a cooperative mammal society

(2017) Faye J. Thompson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational Design of Small Molecules Targeting Oncogenic Noncoding RNAs from Sequence

(2016) Matthew D. Disney et al.   ACCOUNTS OF CHEMICAL RESEARCH

Coexpressed High Levels of VEGF-C and Active MMP-9 Are Associated With Lymphatic Spreading and Local Invasiveness of Papillary Thyroid Carcinoma

(2016) Sonja Šelemetjev et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

(2016) Niels Halama et al.   CANCER CELL

A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation

(2016) Maninjay K. Atianand et al.   CELL

New perspectives on role of tumor microenvironment in progression of cutaneous squamous cell carcinoma

(2016) Liisa Nissinen et al.   CELL AND TISSUE RESEARCH

A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism

(2016) Xi Lan et al.   HEPATOLOGY

The lncRNA HOTAIR impacts on mesenchymal stem cellsviatriple helix formation

(2016) Marie Kalwa et al.   NUCLEIC ACIDS RESEARCH

Design of a small molecule against an oncogenic noncoding RNA

(2016) Sai Pradeep Velagapudi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAM Receptor Signaling in Immune Homeostasis

(2015) Carla V. Rothlin et al.   Annual Review of Immunology

SNAI2/SLUG and estrogen receptor mRNA expression are inversely correlated and prognostic of patient outcome in metastatic non-small cell lung cancer

(2015) Akin Atmaca et al.   BMC CANCER

CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab

(2015) Ganesh Raghu et al.   EUROPEAN RESPIRATORY JOURNAL

Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma

(2015) Xiaoguang Li et al.   GUT

LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment

(2015) Christopher G. Peña et al.   JOURNAL OF CLINICAL INVESTIGATION

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

(2015) Wenchao Zhou et al.   NATURE CELL BIOLOGY

LongTarget: a tool to predict lncRNA DNA-binding motifs and binding sites via Hoogsteen base-pairing analysis

(2014) Sha He et al.   BIOINFORMATICS

A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis

(2014) Shicheng Su et al.   CANCER CELL

Molecular Profiling Reveals a Tumor-Promoting Phenotype of Monocytes and Macrophages in Human Cancer Progression

(2014) Manesh Chittezhath et al.   IMMUNITY

Neuropilin-2 and its ligand VEGF-C predict treatment response after transurethral resection and radiochemotherapy in bladder cancer patients

(2014) B. Keck et al.   INTERNATIONAL JOURNAL OF CANCER

Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers

(2014) Francois Moisan et al.   Molecular Oncology

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

(2014) Laura Bonapace et al.   NATURE

Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

(2013) Andrea Casazza et al.   CANCER CELL

Macrophage Regulation of Tumor Responses to Anticancer Therapies

(2013) Michele De Palma et al.   CANCER CELL

A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors

(2013) Shahneen K. Sandhu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Long Noncoding RNA in Prostate, Bladder, and Kidney Cancer

(2013) Elena S. Martens-Uzunova et al.   EUROPEAN UROLOGY

LncRNA loc285194 is a p53-regulated tumor suppressor

(2013) Qian Liu et al.   NUCLEIC ACIDS RESEARCH

The long noncoding RNA THRIL regulates TNF  expression through its interaction with hnRNPL

(2013) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis

(2012) S. I. Park et al.   CANCER RESEARCH

Tumor-promoting macrophages induce the expression of the macrophage-specific receptor CD163 in malignant cells

(2012) Maciej Bogdan Maniecki et al.   INTERNATIONAL JOURNAL OF CANCER

Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer

(2012) Kenneth J. Pienta et al.   INVESTIGATIONAL NEW DRUGS

hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition

(2012) Suresh Peddigari et al.   NUCLEIC ACIDS RESEARCH

Lymph Node Density Affects Cancer-Specific Survival in Patients with Lymph Node–Positive Urothelial Bladder Cancer Following Radical Cystectomy

(2011) Matthias May et al.   EUROPEAN UROLOGY

Clinical Nodal Staging Scores for Bladder Cancer: A Proposal for Preoperative Risk Assessment

(2011) Shahrokh F. Shariat et al.   EUROPEAN UROLOGY

Lymphatic vessel density as a predictor of lymph node metastasis and its relationship with prognosis in urothelial carcinoma of the bladder

(2010) Mi Zhou et al.   BJU INTERNATIONAL

Multiple Roles of Chemokine (C-C Motif) Ligand 2 in Promoting Prostate Cancer Growth

(2010) J. Zhang et al.   JNCI-Journal of the National Cancer Institute

CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis

(2009) Jian Zhang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Bladder Tumor Infiltrating Mature Dendritic Cells and Macrophages as Predictors of Response to Bacillus Calmette-Guérin Immunotherapy

(2009) Cherifa Ayari et al.   EUROPEAN UROLOGY

The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages

(2008) Paola Allavena et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Prognostic Implications of Lymphangiogenesis in Muscle-Invasive Transitional Cell Carcinoma of the Bladder

(2007) Mario I. Fernández et al.   EUROPEAN UROLOGY