Fucoxanthinol from the Diatom Nitzschia Laevis Ameliorates Neuroinflammatory Responses in Lipopolysaccharide-Stimulated BV-2 Microglia

Assessment of Bioactive Potential of Aqueous Protein Extracts from Diatoms Nitzschia laevis, Spirulina platensis, and Chlorella vulgaris

(2019) Mona Ahmed J. Alzahrani et al.   Journal of Aquatic Food Product Technology

Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway

(2019) Ming-Feng Zhou et al.   CNS Neuroscience & Therapeutics

Fucoxanthin and Rosmarinic Acid Combination Has Anti-Inflammatory Effects through Regulation of NLRP3 Inflammasome in UVB-Exposed HaCaT Keratinocytes

(2019) Azahara Rodríguez-Luna et al.   Marine Drugs

C89 Induces Autophagy of Female Germline Stem Cells via Inhibition of the PI3K-Akt Pathway In Vitro

(2019) Xinyue Li et al.   Cells

Delavatine A, an unusual isoquinoline alkaloid exerts anti-inflammation on LPS-induced proinflammatory cytokines production by suppressing NF-κB activation in BV-2 microglia

(2018) Qing Xie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuroprotective effects of fucoxanthin and its derivative fucoxanthinol from the phaeophyte Undaria pinnatifida attenuate oxidative stress in hippocampal neurons

(2018) Md. Mohibbullah et al.   JOURNAL OF APPLIED PHYCOLOGY

A Hetero-Photoautotrophic Two-Stage Cultivation Process for Production of Fucoxanthin by the Marine Diatom Nitzschia laevis

(2018) Xue Lu et al.   Marine Drugs

Effect of Resveratrol on Oxidative Stress and Mitochondrial Dysfunction in Immature Brain during Epileptogenesis

(2018) Jaroslava Folbergrová et al.   MOLECULAR NEUROBIOLOGY

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

(2018) Sofie Voet et al.   Nature Communications

α-Cyperone inhibits LPS-induced inflammation in BV-2 cells through activation of Akt/Nrf2/HO-1 and suppression of the NF-κB pathway

(2018) Bingxu Huang et al.   Food & Function

Screening and identification of inhibitors of advanced glycation endproduct formation from microalgal extracts

(2018) Peipei Sun et al.   Food & Function

EGCG inhibited bladder cancer T24 and 5637 cell proliferation and migration via PI3K/AKT pathway

(2018) Ke-Wang Luo et al.   Oncotarget

A novel strategy for isolation and purification of fucoxanthinol and fucoxanthin from the diatom Nitzschia laevis

(2018) Peipei Sun et al.   FOOD CHEMISTRY

Protective effects of fucoxanthin and fucoxanthinol against tributyltin-induced oxidative stress in HepG2 cells

(2017) Jie Zeng et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Anti-Inflammatory Activity and Structure-Activity Relationships of Brominated Indoles from a Marine Mollusc

(2017) Tarek Ahmad et al.   Marine Drugs

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways

(2017) Li Zhang et al.   Scientific Reports

PI3k/Akt signalling pathway plays a crucial role in the anti-inflammatory effects of curcumin in LPS-activated microglia

(2016) Antonia Cianciulli et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Fucoxanthin, a Marine Carotenoid, Reverses Scopolamine-Induced Cognitive Impairments in Mice and Inhibits Acetylcholinesterase in Vitro

(2016) Jiajia Lin et al.   Marine Drugs

Differential Activation of Mitogen-Activated Protein Kinases, ERK 1/2, p38MAPK and JNK p54/p46 During Postnatal Development of Rat Hippocampus

(2015) Ana Paula Costa et al.   NEUROCHEMICAL RESEARCH

Cucurbitacins attenuate microglial activation and protect from neuroinflammatory injury through Nrf2/ARE activation and STAT/NF-κB inhibition

(2015) Sun Young Park et al.   NEUROSCIENCE LETTERS

Curcumenol isolated from Curcuma zedoaria suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells

(2015) Jia Ye Lo et al.   Food & Function

Induction of Nrf2-mediated genes by Antrodia salmonea inhibits ROS generation and inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophages

(2015) Hsin-Ling Yang et al.   Food & Function

Inhibitory effects of fucoxanthinol on the viability of human breast cancer cell lines MCF-7 and MDA-MB-231 are correlated with modulation of the NF-kappaB pathway

(2014) Arlette Rwigemera et al.   CELL BIOLOGY AND TOXICOLOGY

Comparative effect of fucoxanthin and vitamin C on oxidative and functional parameters of human lymphocytes

(2014) Nathalia Molina et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Redox activation of Nrf2 & NF-κB: A double end sword?

(2013) Mabel Buelna-Chontal et al.   CELLULAR SIGNALLING

Fucoxanthin Ameliorates Inflammation and Oxidative Reponses in Microglia

(2013) Ratih Pangestuti et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells

(2013) Junghyung Park et al.   JOURNAL OF NEUROCHEMISTRY

Isoorientin attenuates lipopolysaccharide-induced pro-inflammatory responses through down-regulation of ROS-related MAPK/NF-κB signaling pathway in BV-2 microglia

(2013) Li Yuan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging

(2013) Ayesha Maqbool et al.   Molecular Neurodegeneration

Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages

(2013) Hong-Guang Chen et al.   International Journal of Surgery

Procyanidins from Wild Grape (Vitis amurensis) Seeds Regulate ARE-Mediated Enzyme Expression via Nrf2 Coupled with p38 and PI3K/Akt Pathway in HepG2 Cells

(2012) Min-Ji Bak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fucoxantin: A Treasure from the Sea

(2012) Nicolantonio D’Orazio et al.   Marine Drugs

Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells

(2011) Hye Young Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Echinacea Alkamides Prevent Lipopolysaccharide/d-Galactosamine- Induced Acute Hepatic Injury through JNK Pathway-Mediated HO-1 Expression

(2011) Chia-Chung Hou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Fucoxanthin, a Marine Carotenoid Present in Brown Seaweeds and Diatoms: Metabolism and Bioactivities Relevant to Human Health

(2011) Juan Peng et al.   Marine Drugs

Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)-κB and NF-κB-regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis

(2011) Ji H. Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas

(2010) Kei Yamamoto et al.   CANCER LETTERS

Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages

(2010) Soo-Jin Heo et al.   FOOD AND CHEMICAL TOXICOLOGY

The Nrf2 System as a Potential Target for the Development of Indirect Antioxidants

(2010) Kyeong-Ah Jung et al.   MOLECULES

Upstream reactive oxidative species (ROS) signals in exogenous oxidative stress-induced mitochondrial dysfunction

(2009) Min Lu et al.   CELL BIOLOGY INTERNATIONAL

Inhibitory effects of microalgal extracts on the formation of advanced glycation endproducts (AGEs)

(2009) Zheng Sun et al.   FOOD CHEMISTRY

A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

(2009) Jiyoung Kim et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Inflammation, microglia, and alzheimer's disease

(2009) Brent Cameron et al.   NEUROBIOLOGY OF DISEASE

Oleic acid reduces lipopolysaccharide-induced expression of iNOS and COX-2 in BV2 murine microglial cells: Possible involvement of reactive oxygen species, p38 MAPK, and IKK/NF-κB signaling pathways

(2009) Young Taek Oh et al.   NEUROSCIENCE LETTERS

Increased intestinal inflammatory response and gut barrier dysfunction in Nrf2-deficient mice after traumatic brain injury

(2008) Wei Jin et al.   CYTOKINE

Antiadult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol

(2008) Chie Ishikawa et al.   INTERNATIONAL JOURNAL OF CANCER