Article
Chemistry, Medicinal
Catarina Lourenco-Lopes, Aurora Silva, Paula Garcia-Oliveira, Anton Soria-Lopez, Javier Echave, Clara Grosso, Lucia Cassani, Maria Fatima Barroso, Jesus Simal-Gandara, Maria Fraga-Corral, Miguel A. Prieto
Summary: This study investigated the kinetic behavior of Fucoxanthin (Fx) and optimized the time, temperature, and ethanol concentration variables for the best Fx yield from Undaria pinnatifida using conventional heat extraction. The content, extraction yield, and purity of Fx were determined and the optimal conditions for each were identified. The results provide valuable information for potential applications in various industries and can help reduce energy and solvent consumption while maximizing extraction yields.
Article
Chemistry, Medicinal
Catarina Lourenco-Lopes, Anxo Carreira-Casais, Maria Carperna, Marta Barral-Martinez, Franklin Chamorro, Cecilia Jimenez-Lopez, Lucia Cassani, Jesus Simal-Gandara, Miguel A. A. Prieto
Summary: This study optimized the extraction conditions of fucoxanthin (Fx) from U. pinnatifida using emerging techniques, such as microwave-assisted extraction (MAE) and ultrasound-assisted extraction (UAE). The highest Fx concentrations obtained were 58.83 mg Fx/g E for MAE and 124.39 mg Fx/g E for UAE, with short extraction times and low energy consumption. These results can be further explored for industrial applications.
Article
Food Science & Technology
Kyo-Yeon Lee, Jong Min Kim, Jiyeon Chun, Ho Jin Heo, Chae Eun Park, Sung-Gil Choi
Summary: This study investigated the effects of different relative humidities on the microbial safety, antioxidant activity, ascorbic acid, fucoxanthin, and tocopherol contents of Undaria pinnatifida sporophyll powder stored for 4 weeks. The caking phenomenon occurred at high relative humidity levels, leading to quality losses. The stability of ascorbic acid, fucoxanthin, and tocopherol varied with different relative humidity conditions. The sample stored at 69% relative humidity showed the highest antioxidant activity.
Article
Biochemistry & Molecular Biology
Catarina Lourenco-Lopes, Maria Fraga-Corral, Anton Soria-Lopez, Bernabe Nunes-Estevez, Marta Barral-Martinez, Aurora Silva, Ningyang Li, Chao Liu, Jesus Simal-Gandara, Miguel A. Prieto
Summary: Brown macroalgae, particularly Undaria pinnatifida, is a potential source of fucoxanthin (Fx), a pigment with various bioactivities. This study optimized the conditions for conventional heat extraction (CHE) to maximize the recovery of Fx from Undaria pinnatifida. The Fx-rich extracts showed strong antioxidant and antimicrobial activities, especially against gram-positive bacteria. In silico analysis supported these findings and revealed potential molecular interactions of Fx. This research demonstrates the efficiency of CHE for extracting high amounts of Fx and highlights its potential applications in different industries.
Article
Nutrition & Dietetics
Shipeng Yin, Liqiong Niu, Mario Shibata, Yuanfa Liu, Tomoaki Hagiwara
Summary: This study explores the optimal preparation technology of fucoxanthin from waste Undaria pinnatifida stems using supercritical carbon dioxide methods and provides approaches for the extraction and preparation of bioactive compounds from waste seaweed. The results confirm the effectiveness of supercritical fluid extraction technology in preparing fucoxanthin from waste marine resources.
FRONTIERS IN NUTRITION
(2022)
Article
Agricultural Engineering
J. Queffelec, N. Florez-Fernandez, H. Dominguez, M. D. Torres
Summary: Microwave hydrothermal processing was used to extract valuable components from U. pinnatifida, with different processing conditions impacting antioxidant properties and content of minerals, proteins, and oligosaccharides. The most suitable temperature for extracting alginates was found to be 160 degrees C, showing potential for non-food applications after incorporation into alginate matrices. Selected extracts exhibited promising biological activities against human cancer cell lines after an intensification stage, with high cellular inhibition percentages observed.
BIORESOURCE TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Diana Paula Quezada, Maria Lujan Flores, Osvaldo Leon Cordoba
Summary: The alga Undaria pinnatifida from Golfo San Jorge region was studied for its chemical profile and biological activity. The results showed it synthesized various bioactive metabolites, with differences according to the season. The alga exhibited potential as a source of bioactive molecules, and seasonal studies were important for determining the best collection season based on the metabolites to be studied.
JOURNAL OF APPLIED PHYCOLOGY
(2023)
Article
Food Science & Technology
Bernardo Pedro, Laura Guedes, Rebeca Andre, Helena Gaspar, Pedro Vaz, Lia Ascensao, Ricardo Melo, Maria Luisa Serralheiro
Summary: The study found that a soup prepared from this seaweed may contain bioactive compounds, such as phlorotannins and small peptides, that could promote gastrointestinal motility and reduce cholesterol biosynthesis.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Environmental Sciences
M. Nomura, H. Okamura, Y. Horie, C. K. Yap, C. Emmanouil, S. Uwai, H. Kawai
Summary: This study aimed to develop a new phytotoxicity test using the gametophytes of Undaria pinnatifida to evaluate the effects of commonly used antifouling chemicals on seaweeds. The toxicity of Cybutryne, Diuron, Cu2+, and Zn2+ to the gametophytes was assessed by measuring the relative growth rate at the logarithmic growth phase. The test method showed high sensitivity and reproducibility, making it a valuable addition to routine toxicity evaluation of hazardous chemicals.
Article
Chemistry, Medicinal
Wenhui Jin, Ting Yang, Hui Chen, Hua Fang, Weizhu Chen, Quanling Xie, Qian Liu, Yiping Zhang, Zhuan Hong, Guangya Zhang
Summary: A novel approach to produce high-purity fucoxanthinol (FXOH) was developed by fusing cholesterol esterase and SpyTag genes and expressing them in Escherichia coli. The resulting fusion chimera self-assembled into insoluble active aggregates, providing carrier-free immobilization. The conversion ratio and purity achieved by this method were significantly higher than conventional methods.
Article
Allergy
Ali H. Ziyab, A. Daniel Jones, Su Chen, Thilani M. Anthony, Nandini Mukherjee, Syed Hasan Arshad, Wilfried Karmaus
Summary: Increased levels of fucoxanthinol 3-arachidate measured in maternal serum at birth are associated with reduced eczema risk during the first 4 years of the offspring life.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)
Article
Allergy
Ali H. Ziyab, A. Daniel Jones, Su Chen, Thilani M. Anthony, Nandini Mukherjee, Syed Hasan Arshad, Wilfried Karmaus
Summary: Increased levels of fucoxanthinol 3-arachidate measured in maternal serum at birth are associated with reduced eczema risk during the first 4 years of the child's life.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Fengzhi Qiao, Xiaoting Yu, Shanshan Tie, Yannan Chen, Shuai Hou, Mingqian Tan
Summary: Food-borne nanoparticles from Undaria pinnatifida (UPFNs) were successfully utilized as nanocarriers for zinc delivery, showing high solubility and safety with the ability to rescue zinc-deficient cells.
Article
Food Science & Technology
Shan Jiang, Meiqi Yu, Yingzhen Wang, Wei Yin, Pengfei Jiang, Bixiang Qiu, Hang Qi
Summary: This study evaluated the effects of traditional cooking methods on the color, texture, and bioactive nutrients of Undaria pinnatifida and found that blanching and boiling were the more suitable methods.
Article
Chemistry, Applied
Naoki Takatani, Kana Sakimura, Kodai Nagata, Fumiaki Beppu, Yumiko Yamano, Takashi Maoka, Masashi Hosokawa
Summary: By feeding mice a diet containing fucoxanthin, it was found that fucoxanthinol and amarouciaxanthin A-3-esters mainly accumulated in the liver and adipose tissue, while they were less detectable in the serum and other tissues. Thus, it is suggested that fucoxanthinol and amarouciaxanthin A are partially acylated in the liver and adipose tissue after being transported through the body as their free forms.
Article
Biochemistry & Molecular Biology
Md. Mohibbullah, Khawaja Muhammad Imran Bashir, Sung-Kew Kim, Yong-Ki Hong, Andre Kim, Sae-Kwang Ku, Jae-Suk Choi
JOURNAL OF FOOD BIOCHEMISTRY
(2019)
Review
Plant Sciences
Md Abdul Hannan, Abdullah Al Mamun Sohag, Raju Dash, Md Nazmul Haque, Md Mohibbullah, Diyah Fatimah Oktaviani, Md Tahmeed Hossain, Ho Jin Choi, Il Soo Moon
Article
Biochemistry & Molecular Biology
Md. Abdul Hannan, Md. Nazmul Haque, Md. Mohibbullah, Raju Dash, Yong-Ki Hong, Il Soo Moon
Review
Chemistry, Medicinal
Md Abdul Hannan, Raju Dash, Md Nazmul Haque, Md Mohibbullah, Abdullah Al Mamun Sohag, Md Ataur Rahman, Md Jamal Uddin, Mahboob Alam, Il Soo Moon
Article
Food Science & Technology
Md. Abdul Baten, Na Eun Won, Md. Mohibbullah, Sung-Joon Yoon, Jae Hak Sohn, Jin-Soo Kim, Jae-Suk Choi
FOOD SCIENCE & NUTRITION
(2020)
Article
Food Science & Technology
Md Abdul Baten, Na Eun Won, Jae Hak Sohn, Jin-Soo Kim, Md Mohibbullah, Jae-Suk Choi
Article
Chemistry, Multidisciplinary
Jin-Ryul Hu, Chul-Jong Jung, Seong-Min Ku, Dae-Hwa Jung, Sae-Kwang Ku, Md Mohibbullah, Hae-Jeung Lee, Jae-Suk Choi
Summary: SKOG, a mixed preparation of herbal powders, showed significant anti-inflammatory, antitussive and expectorant effects in animal experiments. By oral administration, it reduced respiratory inflammation, increased mucosal thickness and mucus secretion, inhibited allergic inflammation, and decreased ear inflammation, indicating its potential therapeutic effects.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Multidisciplinary
Md. Masud Rana, Md. Mohibbullah, Na Eun Won, Md. Abdul Baten, Jae Hak Sohn, Jin-Soo Kim, Jae-Suk Choi
Summary: The combination of superheated steam roasting and hot smoking was applied to Chub mackerel fillets to extend shelf-life, improve sensory properties, physicochemical, microbial, and nutritional properties, and promote shelf life during storage. The processed CM offered high nutritional value and reduced trimethylamine-N-oxide level, indicating quality and safety with high nutritional standards.
APPLIED SCIENCES-BASEL
(2021)
Review
Chemistry, Medicinal
Md. Mohibbullah, Md. Nazmul Haque, Abdullah Al Mamun Sohag, Md. Tahmeed Hossain, Md. Sarwar Zahan, Md. Jamal Uddin, Md. Abdul Hannan, Il Soo Moon, Jae-Suk Choi
Summary: Fucoxanthin, a natural antioxidant pigment found in marine algae, has potential benefits for human health and disease management. It has attracted significant attention from the scientific community but more clinical research is needed.
Article
Food Science & Technology
Woo-Hee Cho, Jung-Min Park, Eun-Ji Kim, Md. Mohibbullah, Jae-Suk Choi
Summary: In this study, the processing conditions of bee drone pupae powder were investigated, and a puffed-rice snack enriched with the powder and honey was developed. The results showed that the processed product had higher nutritional content and satisfactory safety.
Article
Neurosciences
Md. Mohibbullah, Michael Yordan Pringgo Wicaksono, Md. Abdul Hannan, Raju Dash, Maria Dyah Nur Meinita, Jae-Suk Choi, Yong-Ki Hong, Il Soo Moon
Summary: This study aimed to investigate the protective effects of Gelidium amansii extract (GAE) against scopolamine-induced cognitive deficits and its modulatory effects on hippocampal plasticity in mice. The results showed that GAE administration significantly improved memory deficits in mice, as indicated by increased latency time on the passive avoidance test and decreased errors and latency time on the radial arm maze test. Microscopic observations and immunohistochemistry analysis also revealed improved spine density, synaptic contact, and the recruitment of memory-associated proteins in GAE-treated mice. These findings suggest that GAE could be a potential functional food and a promising source of pharmacological agents for memory-related brain disorders.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS
(2023)
Review
Chemistry, Multidisciplinary
Md Selim Ahmed, Md Jamal Uddin, Muhammad Jahangir Hossen, Md Ataur Rahman, Md Mohibbullah, Md Abdul Hannan, Jae-Suk Choi
Summary: This review examines the impact of plant materials and their phytochemicals on DC-based cancer immunotherapy. It discusses the potential of various plants and their bioactive compounds in modulating the immune system and signaling pathways involved in anti-tumor immunity. However, most of the studies are limited by either preclinical models or crude plant extracts.
APPLIED SCIENCES-BASEL
(2022)
Article
Food Science & Technology
Md. Mohibbullah, Al Amin, Md. Abu Talha, Md. Abdul Baten, Md. Masud Rana, Ashfak Ahmed Sabuz, Asif Wares Newaz, Jae-Suk Choi
Summary: The study examined the properties of seaweed-based cookies made from untapped seaweed Ulva intestinalis from Bangladesh coast, including sensory, physicochemical, nutritional, and fatty acid properties. The cookies were formulated with different percentages of seaweed inclusions and were found to be acceptable in sensory analysis. Physicochemical properties were within acceptable limits, and nutritional analysis showed increased lipid and ash contents in the cookies. The fatty acid profile of Ulva intestinalis from Bangladesh was reported for the first time. Overall, cookies with 2.5% powdered Ulva intestinalis and 5% fragmented Ulva intestinalis can be marketed as healthy foods.
Article
Food Science & Technology
Md. Mohibbullah, Md. Abu Talha, Md. Abdul Baten, Asif Wares Newaz, Jae-Suk Choi
Summary: The present study aimed to optimize the extraction variables for obtaining food grade quality agar from Gracilaria tenuistipitata, which is the first study on Bangladeshi seaweed. Water- and NaOH-pretreated agars were compared based on several physicochemical parameters. The extraction variables significantly influenced the agar yield in both conditions. NaOH-pretreated agar showed better yield and gel strength compared to water-pretreated agar. Parameters such as NaOH concentration, temperature, and extraction time were optimized to obtain the highest agar yield. The obtained agar had comparable characteristics with commercial agar and showed antioxidant activity.
FOOD SCIENCE & NUTRITION
(2023)
Review
Business
Khawaja Muhammad Imran Bashir, Jin-Soo Kim, Md Mohibbullah, Jae Hak Sohn, Jae-Suk Choi
JOURNAL OF ISLAMIC MARKETING
(2019)
