Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways

Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes

(2016) Marta Pajares et al.   Autophagy

Protective Effect of Fucoxanthin Isolated from Laminaria japonica against Visible Light-Induced Retinal Damage Both in Vitro and in Vivo

(2016) Yixiang Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Fucoxanthin, a Marine Carotenoid, Reverses Scopolamine-Induced Cognitive Impairments in Mice and Inhibits Acetylcholinesterase in Vitro

(2016) Jiajia Lin et al.   Marine Drugs

Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells

(2016) Yugang Liu et al.   NEUROCHEMICAL RESEARCH

Traumatic Brain Injury-Induced Neuronal Apoptosis is Reduced Through Modulation of PI3K and Autophagy Pathways in Mouse by FTY720

(2015) Li Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

(2015) Lulu Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Anti-Obesity Activity of the Marine Carotenoid Fucoxanthin

(2015) Maria Gammone et al.   Marine Drugs

Homocysteine and cytosolic GSH depletion induce apoptosis and oxidative toxicity through cytosolic calcium overload in the hippocampus of aged mice: Involvement of TRPM2 and TRPV1 channels

(2015) İ.S. Övey et al.   NEUROSCIENCE

Posttraumatic administration of luteolin protects mice from traumatic brain injury: Implication of autophagy and inflammation

(2014) Jianguo Xu et al.   BRAIN RESEARCH

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

(2014) Ke Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fucoxanthin Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes

(2014) Jian Zheng et al.   Marine Drugs

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Long-Term Disability and Survival in Traumatic Brain Injury: Results From the National Institute on Disability and Rehabilitation Research Model Systems

(2013) Jordan C. Brooks et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

A purified Feverfew extract protects from oxidative damage by inducing DNA repair in skin cells via a PI3-kinase-dependent Nrf2/ARE pathway

(2013) Karien J. Rodriguez et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo

(2012) Yongbo Zhao et al.   EXPERIMENTAL NEUROLOGY

Nrf2 activation prevents cadmium-induced acute liver injury

(2012) Kai C. Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protective effect of tert-butylhydroquinone on cerebral inflammatory response following traumatic brain injury in mice

(2011) Wei Jin et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Fucoxanthin Enhances HO-1 and NQO1 Expression in Murine Hepatic BNL CL.2 Cells through Activation of the Nrf2/ARE System Partially by Its Pro-oxidant Activity

(2011) Cheng-Ling Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage

(2011) Gang Chen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Modulation of Transcription Factor Nrf2 in an In Vitro Model of Traumatic Brain Injury

(2011) Haris Hatic et al.   JOURNAL OF NEUROTRAUMA

Regulation of the Nrf2–Keap1 Antioxidant Response by the Ubiquitin Proteasome System: An Insight into Cullin-Ring Ubiquitin Ligases

(2010) Nicole F. Villeneuve et al.   ANTIOXIDANTS & REDOX SIGNALING

A reporter cell system to monitor autophagy based on p62/SQSTM1

(2010) Kenneth Bowitz Larsen et al.   Autophagy

Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy

(2010) Weiliang Fan et al.   Autophagy

Neuroprotective effects of pioglitazone in a rat model of permanent focal cerebral ischemia are associated with peroxisome proliferator-activated receptor gamma-mediated suppression of nuclear factor-κB signaling pathway

(2010) H.-L. Zhang et al.   NEUROSCIENCE

Mouse closed head injury model induced by a weight-drop device

(2009) Michael A Flierl et al.   Nature Protocols

The Expression of NF-E2-Related Factor 2 in the Rat Brain After Traumatic Brain Injury

(2009) Wei Yan et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?

(2008) Helga E. de Vries et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structural basis of target recognition by Atg8/LC3 during selective autophagy

(2008) Nobuo N. Noda et al.   GENES TO CELLS

Activation of Nrf2–ARE pathway in brain after traumatic brain injury

(2008) Wei Yan et al.   NEUROSCIENCE LETTERS

Autophagy is activated and might protect neurons from degeneration after traumatic brain injury

(2008) Yan-Bo Zhang et al.   Neuroscience Bulletin