Genetic variants that associate with cirrhosis have pleiotropic effects on human traits
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Title
Genetic variants that associate with cirrhosis have pleiotropic effects on human traits
Authors
Keywords
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Journal
LIVER INTERNATIONAL
Volume 40, Issue 2, Pages 405-415
Publisher
Wiley
Online
2019-12-09
DOI
10.1111/liv.14321
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- (2018) Noura S. Abul-Husn et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2018) AM Attallah et al. BRITISH JOURNAL OF BIOMEDICAL SCIENCE
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- (2018) Virginia C. Clark et al. JOURNAL OF HEPATOLOGY
- The association between PIN1 genetic polymorphisms and the risk of chronic hepatitis B and hepatitis B virus-related liver cirrhosis
- (2018) Li Huang et al. MEDICINE
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- (2018) Lillias H. Maguire et al. NATURE GENETICS
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- (2018) Wei Zhou et al. NATURE GENETICS
- Effect of MBOAT7 variant on hepatitis B and C infections in Moroccan patients
- (2018) Sayeh Ezzikouri et al. Scientific Reports
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- (2018) Yanling Ma et al. HEPATOLOGY
- PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases
- (2018) Jie Yang et al. INTERNATIONAL JOURNAL OF CANCER
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- (2018) Oriol Canela-Xandri et al. NATURE GENETICS
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- Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns
- (2017) Daniel Seung Kim et al. JOURNAL OF LIPID RESEARCH
- Functional mapping and annotation of genetic associations with FUMA
- (2017) Kyoko Watanabe et al. Nature Communications
- IL-18 polymorphisms contribute to hepatitis B virus-related cirrhosis and hepatocellular carcinoma susceptibility in Chinese population: a case-control study
- (2017) Zhi-Jun Dai et al. Oncotarget
- Magnetic resonance elastography identifies fibrosis in adults with alpha-1 antitrypsin deficiency liver disease: a prospective study
- (2016) R. G. Kim et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- PNPLA3 gene in liver diseases
- (2016) Eric Trépo et al. JOURNAL OF HEPATOLOGY
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- (2016) Yingchang Lu et al. Nature Communications
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- (2016) Khaled Thabet et al. Nature Communications
- Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
- (2016) Johannes Kettunen et al. Nature Communications
- α1-Antitrypsin deficiency
- (2016) Catherine M. Greene et al. Nature Reviews Disease Primers
- Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study
- (2015) Rohit Loomba et al. GASTROENTEROLOGY
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- (2015) Robert J. Wong et al. GASTROENTEROLOGY
- The dual and opposite role of theTM6SF2-rs58542926 variant in protecting against cardiovascular disease and conferring risk for nonalcoholic fatty liver: A meta-analysis
- (2015) Carlos J. Pirola et al. HEPATOLOGY
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- (2015) Dmitry Shungin et al. NATURE
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- (2015) De-Ke Jiang et al. Scientific Reports
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis
- (2014) Ali A Mokdad et al. BMC Medicine
- Impact of common risk factors of fibrosis progression in chronic hepatitis C
- (2014) S Rüeger et al. GUT
- Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis
- (2014) F. Stickel et al. HUMAN MOLECULAR GENETICS
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- (2014) Oddgeir L Holmen et al. NATURE GENETICS
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- (2013) Cristen J Willer et al. NATURE GENETICS
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- (2012) Mahendra S. Nehra et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
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- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
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