Pharmacological HIF1 Inhibition Eliminates Downregulation of the Pentose Phosphate Pathway and Prevents Neuronal Apoptosis in Rat Hippocampus Caused by Severe Hypoxia

Deletion of NADPH oxidase 4 reduces severity of traumatic brain injury

(2018) Merry W. Ma et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroprotective Mechanism of Hypoxic Post-conditioning Involves HIF1-Associated Regulation of the Pentose Phosphate Pathway in Rat Brain

(2018) Oleg Vetrovoy et al.   NEUROCHEMICAL RESEARCH

Neuroprotective effect of hypobaric hypoxic postconditioning is accompanied by dna protection and lipid peroxidation changes in rat hippocampus

(2017) Oleg Vetrovoy et al.   NEUROSCIENCE LETTERS

β2-Adrenergic Receptor-Mediated HIF-1α Upregulation Mediates Blood Brain Barrier Damage in Acute Cerebral Ischemia

(2017) Yanyun Sun et al.   Frontiers in Molecular Neuroscience

Cannabidiol attenuates OGD/R-induced damage by enhancing mitochondrial bioenergetics and modulating glucose metabolism via pentose-phosphate pathway in hippocampal neurons

(2017) Shanshan Sun et al.   Redox Biology

Thiamine deficiency activates hypoxia inducible factor-1α to facilitate pro-apoptotic responses in mouse primary astrocytes

(2017) Kristy Zera et al.   PLoS One

Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion

(2016) Daniel Gruneberg et al.   EXPERIMENTAL NEUROLOGY

Neuronal HIF-1α and HIF-2α deficiency improves neuronal survival and sensorimotor function in the early acute phase after ischemic stroke

(2016) Philipp Barteczek et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mitochondrial dynamics following global cerebral ischemia

(2016) Rita Kumar et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The pattern of the expression of hypoxia-inducible factor (HIF-1α) in the neocortex and hippocampus of rats after the presentation of different modes of hypobaric hypoxia

(2015) M. O. Samoilov et al.   Neurochemical Journal

Reduced Nicotinamide Adenine Dinucleotide Phosphate, a Pentose Phosphate Pathway Product, Might Be a Novel Drug Candidate for Ischemic Stroke

(2015) Mei Li et al.   STROKE

Mitochondria-controlled signaling mechanisms of brain protection in hypoxia

(2015) Ludmila D. Lukyanova et al.   Frontiers in Neuroscience

Hypoxic preconditioning protection is eliminated in HIF-1α knockout mice subjected to neonatal hypoxia–ischemia

(2014) R. Ann Sheldon et al.   PEDIATRIC RESEARCH

Transcriptional regulation by hypoxia inducible factors

(2013) Veronica L. Dengler et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: From ferroptosis to stroke

(2013) Rachel E. Speer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant and bioenergetic coupling between neurons and astrocytes

(2012) Seila Fernandez-Fernandez et al.   BIOCHEMICAL JOURNAL

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

(2012) Marcel Deponte   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy

(2012) T. W. H. Meijer et al.   CLINICAL CANCER RESEARCH

Molecular Mechanisms of Ischemia–Reperfusion Injury in Brain: Pivotal Role of the Mitochondrial Membrane Potential in Reactive Oxygen Species Generation

(2012) Thomas H. Sanderson et al.   MOLECULAR NEUROBIOLOGY

Postconditioning by mild hypoxic exposures reduces rat brain injury caused by severe hypoxia

(2012) Elena Rybnikova et al.   NEUROSCIENCE LETTERS

Expression of glucocorticoid and mineralocorticoid receptors in hippocampus of rats exposed to various modes of hypobaric hypoxia: Putative role in hypoxic preconditioning

(2011) Elena Rybnikova et al.   BRAIN RESEARCH

Hypoxia-inducible factor inhibitors: a survey of recent patented compounds (2004 – 2010)

(2011) Hyun Seung Ban et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors

(2011) Ya-Min Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotection by Dimethyloxalylglycine following Permanent and Transient Focal Cerebral Ischemia in Rats

(2010) Simon Nagel et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Alcohol based tissue fixation as an alternative for formaldehyde: influence on immunohistochemistry

(2010) H. F. van Essen et al.   JOURNAL OF CLINICAL PATHOLOGY

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

(2009) A. Rapisarda et al.   MOLECULAR CANCER THERAPEUTICS

Early inhibition of HIF-1α with small interfering RNA reduces ischemic–reperfused brain injury in rats

(2009) Chunhua Chen et al.   NEUROBIOLOGY OF DISEASE

Changes in lipid peroxidation in the hippocampus and neocortex after severe hypobaric hypoxia in rats

(2009) M. S. Kislin et al.   Neurochemical Journal

Crystal Structure and Catalysis of the Selenoprotein Thioredoxin Reductase 1

(2008) Qing Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose up-regulates HIF-1α expression in primary cortical neurons in response to hypoxia through maintaining cellular redox status

(2008) Shuhong Guo et al.   JOURNAL OF NEUROCHEMISTRY

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α

(2008) Michela Guglielmotto et al.   JOURNAL OF NEUROCHEMISTRY